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CORC

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Quantitative palaeogeographical reconstruction of the North China Block during the Carboniferous and Permian transition: Implications for coal accumulation and source rock development 期刊论文
Palaeogeography, Palaeoclimatology, Palaeoecology, 2024, 卷号: 640, 页码: 112102
作者:  Shen, Boheng;  Hou, Zhangshuai;  Wang, Xiangdong;  Wu, Qiong;  Zhang, Hua(张华)
收藏  |  浏览/下载：3/0  |  提交时间：2024/04/15
An overview of kinase downregulators and recent advances in discovery approaches 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6
作者:  Wang, Beilei;  Wu, Hong;  Hu, Chen;  Wang, Haizhen;  Liu, Jing
收藏  |  浏览/下载：39/0  |  提交时间：2022/01/25
DRAK2 aggravates nonalcoholic fatty liver disease progression through SRSF6-associated RNA alternative splicing 期刊论文
CELL METABOLISM, 2021, 卷号: 33, 期号: 10, 页码: 2004-+
作者:  Li, Yufeng;  Xu, Junyu;  Lu, Yuting;  Bian, Hua;  Yang, Lin
收藏  |  浏览/下载：23/0  |  提交时间：2022/01/18
Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML) 期刊论文
CANCER BIOLOGY & THERAPY, 2019, 卷号: 20, 期号: 6, 页码: 877-885
作者:  Wu, Jiaxin;  Wang, Aoli;  Li, Xixiang;  Chen, Cheng;  Qi, Ziping
收藏  |  浏览/下载：29/0  |  提交时间：2019/11/27
Discovery of 2-(4-Chloro-3-(trifluoromethyl)phenyl)-N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)acetamide (CHMFL-KIT-64) as a Novel Orally Available Potent Inhibitor against Broad-Spectrum Mutants of 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019
作者:  Yun Wu;  Beilei Wang;  Junjie Wang;  Qi S(亓爽);  Fengming Zou
收藏  |  浏览/下载：62/0  |  提交时间：2020/10/20
上调微小RNA-142-3p对心肌肥厚中线粒体功能的影响 期刊论文
South China Journal of Cardiovascular Diseases, 2019, 期号: 02
作者:  刘蓓蕾;  王顺;  胡珊;  王乐;  吴钢
收藏  |  浏览/下载：6/0  |  提交时间：2019/12/05
Down-regulation of miR-200c attenuates Angll-induced cardiac hypertrophy via targeting the MLCK-mediated pathway 期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 卷号: 23, 期号: 4
作者:  Hu, Shan;  Cheng, Mian;  Guo, Xin;  Wang, Shun;  Liu, Beilei
收藏  |  浏览/下载：26/0  |  提交时间：2019/12/05
Repurposing cabozantinib to GISTs: Overcoming multiple imatinib-resistant cKIT mutations including gatekeeper and activation loop mutants in GISTs preclinical models 期刊论文
CANCER LETTERS, 2019, 页码: 105-114
作者:  Lu, Tingting;  Chen, Cheng;  Wang, Aoli;  Jiang, Zongru;  Qi, Ziping
收藏  |  浏览/下载：12/0  |  提交时间：2020/07/14
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen
收藏  |  浏览/下载：14/0  |  提交时间：2019/01/11
Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino) cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl) tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 896-916
作者:  Wang, Beilei;  Wu, Jiaxin;  Wu, Yun;  Chen, Cheng;  Zou, Fengming
收藏  |  浏览/下载：65/0  |  提交时间：2019/12/25

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