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中国医学科学院 北京... [7]
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上海药物研究所 [2]
新疆理化技术研究所 [2]
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期刊论文 [30]
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Discovery of novel ketoxime ether derivatives with potent FXR agonistic activity, oral effectiveness and high liver/blood ratio
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 43, 页码: 13
作者:
Tang, Xuehang
;
Ning, Mengmeng
;
Ye, Yangliang
;
Gu, Yipei
;
Yan, Hongyi
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/11/04
FXR agonist
Ketoxime ether
Target genes
Liver
blood ratio
Systemic activation
Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 21, 页码: 12748-12772
作者:
Li, Junyou
;
Liu, Mengqi
;
Li, Yazhou
;
Sun, Dan-dan
;
Shu, Zhihao
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
PD-1 inhibitor combined with apatinib for advanced gastric or esophagogastric junction cancer: a retrospective study
期刊论文
TRANSLATIONAL CANCER RESEARCH, 2020, 卷号: 9
作者:
Wei, Qing
;
Yuan, Xing
;
Li, Jingjing
;
Xu, Qi
;
Ying, Jieer
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/11/30
Programmed death 1 (PD-1)
gastric cancer (GC)
immune checkpoint inhibitors
immunotherapy
apatinib
Risk of dermatologic and mucosal adverse events associated with PD-1/PD-L1 inhibitors in cancer patients A meta-analysis of randomized controlled trials
期刊论文
MEDICINE, 2019, 卷号: 98, 期号: 20
作者:
Yang, Wenwei
;
Li, Shuquan
;
Yang, Qingrui
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
alopecia
cancer
immune-related adverse events
meta-analysis
mucosal
inflammation
PD-1 inhibitors
PD-L1 inhibitors
pruritus
rash
stomatitis
vitiligo
Incidence and risk factors for epidural morphine induced pruritus in parturients receiving cesarean section: A prospective multicenter observational study
期刊论文
2019, 卷号: 98, 期号: 40, 页码: e17366
作者:
Tan Xiao
;
Shen Le
;
Wang Lin
;
Labaciren
;
Zhang Yuelun
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/03
Risk factors for hypertrophic burn scar pain, pruritus, and paresthesia development
期刊论文
WOUND REPAIR AND REGENERATION, 2018, 卷号: 26, 期号: 2
作者:
Xiao, Yongqiang
;
Sun, Yu
;
Zhu, Banghui
;
Wang, Kangan
;
Liang, Pengfei
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/04
NMDA receptor antagonists attenuate intrathecal morphine-induced pruritus through ERK phosphorylation
期刊论文
MOLECULAR BRAIN, 2018, 卷号: 11
作者:
Shen, Le
;
Wang, Weijia
;
Li, Siyu
;
Qin, Jing
;
Huang, Yuguang
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Intrathecal morphine
pruritus
analgesia
NMDA receptor antagonist
ERK
A randomized controlled trial for effectiveness of zolpidem versus acupressure on sleep in hemodialysis patients having chronic kidney disease-associated pruritus
期刊论文
MEDICINE, 2018, 卷号: 97, 期号: 31, 页码: e10764
作者:
Rehman, Inayat Ur[1]
;
Bin Chia, David Wu[2]
;
Ahmed, Raheel[3]
;
Khan, Nisar Ahmad[4]
;
Rahman, Aziz Ur[5]
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/24
acupressure
chronic kidney disease-associated pruritus
hemodialysis
Pakistan
quality of life
sleep quality
zolpidem
NMDA receptor antagonists attenuate intrathecal morphine-induced pruritus through ERK phosphorylation
期刊论文
2018, 卷号: 11, 期号: 1, 页码: 35
作者:
Shen, Le
;
Wang, Weijia
;
Li, Siyu
;
Qin, Jing
;
Huang, Yuguang
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/01/03
Intrathecal morphine
pruritus
analgesia
NMDA receptor antagonist
ERK
Specific patterns of spinal metabolites underlying alpha-Me-5-HT-evoked pruritus compared with histamine and capsaicin assessed by proton nuclear magnetic resonance spectroscopy
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2017, 卷号: 1863, 期号: 6, 页码: 1222-1230
作者:
Tian, Xuebi
;
Liu, Taotao
;
Liu, Zeyuan
;
Li, Zhixiao
;
Kamal, Ghulam Mustafa
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2017/12/06
Itch
Spinal Cord
Metabolites
Nuclear Magnetic Resonance Spectroscopy
Gaba
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