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科研机构
上海药物研究所 [6]
内容类型
期刊论文 [6]
发表日期
2018 [2]
2017 [2]
2016 [1]
2015 [1]
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Design and Synthesis of Marine Phidianidine Derivatives as Potential Immunosuppressive Agents
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 24, 页码: 11298-11308
作者:
Liu, Jin
;
Li, Heng
;
Chen, Kai-Xian
;
Zuo, Jian-Ping
;
Guo, Yue-Wei
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/01
Function-Oriented Synthesis of Marine Phidianidine Derivatives as Potential PTP1B Inhibitors with Specific Selectivity
期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 3
作者:
Liu, Jin
;
Chen, Yu
;
Li, Jing-Ya
;
Luo, Cheng
;
Li, Jia
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
phidianidine
marine natural products
PTP1B inhibitor
specific selectivity
docking analysis
Function Oriented Synthesis
structure-activity relationship
Recent Advances in the Isolation, Synthesis and Biological Activity of Marine Guanidine Alkaloids
期刊论文
MARINE DRUGS, 2017, 卷号: 15, 期号: 10
作者:
Liu, Jin
;
Li, Xu-Wen
;
Guo, Yue-Wei
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
marine guanidine alkaloids
sponge
mollusk
ascidian
total synthesis
biological activity
Synthesis and Structural Modification of Marine Natural Products
期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 6
作者:
Zhang, Juan
;
Zhang, Hua
;
Alexandre Muehlmann, Luis
;
Jiang, Cheng-Shi
;
Guo, Yue-Wei
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  |  
浏览/下载:81/0
  |  
提交时间:2019/01/08
marine natural products
total synthesis
structural modification
antitumor activity
enzyme-inhibitory activity
neuroprotective activity
Design, synthesis and in vitro activity of phidianidine B derivatives as novel PTP1B inhibitors with specific selectivity
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 3, 页码: 778-781
作者:
Zhang, Li
;
Jiang, Cheng-Shi
;
Gao, Li-Xin
;
Gong, Jing-Xu
;
Wang, Zhong-Hua
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Phidianidine
Oxadiazole derivative
PTP1B inhibitor
Specific selectivity
Docking analysis
Function-oriented synthesis
Synthesis and biological evaluation of novel marine-derived indole-based 1,2,4-oxadiazoles derivatives as multifunctional neuroprotective agents
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 2, 页码: 216-220
作者:
Jiang, Cheng-Shi
;
Fu, Yan
;
Zhang, Li
;
Gong, Jing-Xu
;
Wang, Zhen-Zhong
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Phidianidines
1,2,4-Oxadiazole derivatives
Amyloid-beta-peptide
Oxygen-glucose deprivation
Neuroprotective activity
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