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科研机构
上海药物研究所 [59]
内容类型
期刊论文 [54]
会议论文 [5]
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2010 [1]
2004 [2]
2003 [6]
2002 [3]
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Paradoxical relationship between RAVE (relative activity versus endocytosis) values of several opioid receptor agonists and their liability to cause dependence
期刊论文
ACTA PHARMACOLOGICA SINICA, 2010, 卷号: 31, 期号: 4, 页码: 393-398
作者:
Wang, Yu-hua
;
Sun, Jian-feng
;
Tao, Yi-min
;
Xu, Xue-jun
;
Chi, Zhi-qiang
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
RAVE
mu-opioid receptor
cyclic AMP
endocytosis
physical dependence
psychological dependence
Colocalization of phosphorylated CREB with calcium/calmodulin-dependent protein kinase IV in hippocampal neurons induced by ohmfentanyl stereoisomers
期刊论文
BRAIN RESEARCH, 2004, 卷号: 1024, 期号: 1-2, 页码: 25-33
作者:
Gao, C
;
Chen, LW
;
Tao, YM
;
Chen, J
;
Xu, XJ
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
ohmfentanyl stereoisomer
cAMP response element-binding protein
Ca2+/calmodulin-dependent protein kinase IV
hippocampal neuron
opioids dependence
phosphorylation
Effect of chronic treatment of ohmefentanyl stereoisomers on cyclic AMP formation in Sf9 insect cells expressing human mu-opioid receptors
期刊论文
LIFE SCIENCES, 2004, 卷号: 74, 期号: 24, 页码: 3001-3008
作者:
Liu, ZH
;
He, Y
;
Jin, WQ
;
Chen, XJ
;
Shen, QX
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
ohmefentanyl stereoisomer
mu-opioid receptor
binding affinity
cyclic AMP
Sf9 insect cell
Effects of ohmefentanyl stereoisomers on phosphorylation of cAMP-response element binding protein in cultured rat hippocampal neurons
期刊论文
ACTA PHARMACOLOGICA SINICA, 2003, 卷号: 24, 期号: 12, 页码: 1253-1258
作者:
Gao, C
;
Chen, LW
;
Tao, YM
;
Chen, J
;
Xu, XJ
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
ohmefentanyl stereoisomers
cAMP-response element binding protein
mu opioid receptor
cyclic AMP
hippocampal neurons
phosphorylation
Binding affinity to and dependence on some opioids in Sf9 insect cells expressing human mu-opioid receptor
期刊论文
ACTA PHARMACOLOGICA SINICA, 2003, 卷号: 24, 期号: 9, 页码: 859-863
作者:
Liu, ZH
;
He, Y
;
Jin, WQ
;
Chen, XJ
;
Zhang, HP
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/01/08
narcotics
mu opioid receptor
competitive binding
cyclic AMP
analgesia
opioid-related disorders
Opioid activity of C8813, a novel and potent opioid analgesic
期刊论文
LIFE SCIENCES, 2003, 卷号: 73, 期号: 2, 页码: 233-241
作者:
Liu, ZH
;
Jin, WQ
;
Dai, QY
;
Chen, XJ
;
Zhang, HP
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
C8813
antinociception
opioid receptor
binding assay
bioassay
Internalization and recycling of human mu opioid receptors expressed in Sf9 insect cells
期刊论文
LIFE SCIENCES, 2003, 卷号: 73, 期号: 1, 页码: 115-128
作者:
Chen, LW
;
Gao, C
;
Chen, J
;
Xu, XJ
;
Zhou, DH
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
G protein coupled receptors
mu-opioid receptor
internalization
recycling
Sf9 insect cells
Synthesis and analgesic activity of stereolsomers of cis-fluoro-ohmefentanyl
期刊论文
PHARMAZIE, 2003, 卷号: 58, 期号: 5, 页码: 300-302
作者:
Zou, Y
;
Wu, H
;
Yuan, WF
;
Dai, QY
;
Chen, XJ
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/01/08
Ohmefentanyl stereoisomers induce changes of CREB phosphorylation in hippocampus of mice in conditioned place preference paradigm
期刊论文
CELL RESEARCH, 2003, 卷号: 13, 期号: 1, 页码: 29-34
作者:
Gao, C
;
Chen, LW
;
Chen, J
;
Xu, XJ
;
Chi, ZQ
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
cAMP-response element binding protein (CREB)
ohmefentanyl stereo isomers
opiates
hippocampus
conditioned place preference (CPP)
3-pyrroline containing arylacetamides: A novel series of remarkably selective kappa-agonists
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2002, 卷号: 12, 期号: 17, 页码: 2287-2290
作者:
Mou, QY
;
Chen, J
;
Zhu, YC
;
Zhou, DH
;
Chi, ZQ
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
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