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上海药物研究所 [8]
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厦门大学 [1]
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期刊论文 [22]
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Anti-DLBCL efficacy of DCZ0825 in vitro and in vivo: involvement of the PI3K-AKT-mTOR/JNK pathway
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2021, 卷号: 53, 期号: 5, 页码: 575-583
作者:
Hu, Ke
;
Li, Bo
;
Ma, Ruye
;
Yi, Hongfei
;
Xu, Zhijian
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2021/06/11
caspase
cell proliferation
cell cycle arrest
diffuse large B-cell lymphoma
PI3K-AKT-mTOR/JNK pathway
Novel cyclophosphamide of natural products osalmide and pterostilbene induces cytotoxicity and cell cycle arrest in diffuse large B-cell lymphoma cells
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2020, 卷号: 52, 期号: 4, 页码: 401-410
作者:
Xi, Mengyu
;
He, Wan
;
Li, Bo
;
Zhou, Jinfeng
;
Xu, Zhijian
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2020/12/24
DCZ0801
DLBCL
apoptosis
cell cycle
MAPK
Novel cyclophosphamide of natural products osalmide and pterostilbene induces cytotoxicity and cell cycle arrest in diffuse large B-cell lymphoma cells
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2020, 卷号: 52, 期号: 4, 页码: 401-410
作者:
Xi, Mengyu
;
He, Wan
;
Li, Bo
;
Zhou, Jinfeng
;
Xu, Zhijian
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/24
DCZ0801
DLBCL
apoptosis
cell cycle
MAPK
Ilamycin C induces apoptosis and inhibits migration and invasion in triple-negative breast cancer by suppressing IL-6/STAT3 pathway
期刊论文
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2019, 卷号: 12, 页码: 60
作者:
Ma, Junying
;
Xie, Qing
;
Yang, Zhijie
;
Huang, Xuanmei
;
Zhang, Zikang
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/09/09
Ilamycin C
Triple-negative breast cancer
Apoptosis
Invasion
Migration
IL-6
STAT3
The neuroprotective mechanism of 2-arachidonoylglycerol 2-AG against non-caspase-dependent apoptosis in mice hippocampal neurons following MCAO
期刊论文
NEUROPSYCHIATRIC DISEASE AND TREATMENT, 2019, 卷号: 15
作者:
Zhong, He-Ying
;
Yang, Zhou
;
Qiu, Zhen
;
Lei, Shao-Qing
;
Xia, Zhong-Yuan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
2-arachidonoylglycerol
hippocampus
nerve cell
non-caspase-dependent pathway
DCZ3301, a novel aryl-guanidino inhibitor, induces cell apoptosis and cell cycle arrest via suppressing the PI3K/AKT pathway in T-cell leukemia/lymphoma
期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2018, 卷号: 50, 期号: 7, 页码: 643-650
作者:
Xiao, Wenqin
;
Li, Bo
;
Sun, Xi
;
Yu, Dandan
;
Xie, Yongsheng
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2019/01/08
DCZ3301
T-cell leukemia/lymphoma
apoptosis
cell cycle
PI3K/AKT
Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer
期刊论文
CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621
作者:
Wang, Jing-Nan
;
Zhang, Zhi-Rong
;
Che, Yun
;
Yuan, Zu-Yang
;
Lu, Zhi-Liang
收藏
  |  
浏览/下载:111/0
  |  
提交时间:2018/07/16
Acetyl-macrocalin B
reactive oxygen species
p38 MAPK
apoptosis
Chk1
Chk2
G2
M phase arrest
NSCLC
Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer
期刊论文
2018, 卷号: 19, 期号: 7, 页码: 609-621
作者:
Wang, Jing-Nan
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/01/03
Acetyl-macrocalin B
reactive oxygen species
p38 MAPK
apoptosis
Chk1
Chk2
G2
M phase arrest
NSCLC
dcz3301anovelarylguanidinoinhibitorinducescellapoptosisandcellcyclearrestviasuppressingthepi3kaktpathwayintcellleukemialymphoma
期刊论文
actabiochimicaetbiophysicasinica, 2018, 卷号: 50, 期号: 7, 页码: 643
作者:
Xiao Wenqin
;
Li Bo
;
Sun Xi
;
Yu Dandan
;
Xie Yongsheng
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
ACUTE LYMPHOBLASTIC-LEUKEMIA
NON-HODGKIN-LYMPHOMA
SIGNALING PATHWAYS
DEATH
PROTEIN
LINES
DCZ3301
T-cell leukemia/lymphoma
apoptosis
cell cycle
PI3K/AKT
A novel fluorinated thiosemicarbazone derivative-2-(3,4-difluorobenzylidene) hydrazinecarbothioamide induces apoptosis in human A549 lung cancer cells via ROS-mediated mitochondria-dependent pathway
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017, 卷号: 491, 期号: 1, 页码: 65-71
作者:
Zhao, Yue
;
Guo, Chuanlong
;
Wang, Lijun
;
Wang, Shuaiyu
;
Li, Xiangqian
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2018/01/11
Thiosemicarbazone
Anticancer
2-(3
Apoptosis
4-difluorobenzylidene) Hydrazinecarbothioamide
Ros
Mitochondria-dependent Pathway
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