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Advances in biosynthesis of peptide drugs: Technology and industrialization
期刊论文
BIOTECHNOLOGY JOURNAL, 2023, 页码: 13
作者:
Wang, Jing
;
Chen, Long
;
Qin, Song
;
Xie, Mingyuan
;
Luo, Shi-Zhong
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/01/26
biosynthesis technology
industrialization
peptide drugs
peptide synthesis
Design, synthesis and biological evaluation of sulfonamides inhibitors of XPO1 displaying activity against multiple myeloma cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235
作者:
Qu, Bingxue
;
Xu, Yongjin
;
Lu, Yang
;
Zhuang, Weihao
;
Jin, Xinxin
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2022/12/23
XPO1
Multiple myeloma
MM.1S
N-phenylsulfonamide
Oral administration
Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge
期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2021, 卷号: 17, 期号: 9, 页码: 19
作者:
Xiong, Zhaoping
;
Jeon, Minji
;
Allaway, Robert J.
;
Kang, Jaewoo
;
Park, Donghyeon
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/11/04
Hypothalamic Melanocortin and Mesencephalic Dopamine Systems Regulate Reward-related Behaviors in Food Intake and Drug Use
期刊论文
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2021, 卷号: 48, 期号: 5, 页码: 541-549
作者:
Liu Ying
;
Liu Chao
;
Lin Qing-Hua
;
Zhang Jian-Jun
;
Du Wen-Jie
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2021/08/07
motivated behavior
drug addiction
dopamine
melanocortin system
proopiomelanocortin neuron
agouti-related protein neuron
Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 216, 页码: 20
作者:
Gao, Dingding
;
Jin, Nan
;
Fu, Yixian
;
Zhu, Yueyue
;
Wang, Yujie
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/06/11
STAT3 signaling pathway
Benzothiazole
Rational design
Antitumor activity
Molecular docking
DeepDRK: a deep learning framework for drug repurposing through kernel-based multi-omics integration
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 5
作者:
Wang, Yongcui
;
Yang, Yingxi
;
Chen, Shilong
;
Wang, Jiguang
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/11/18
drug repurposing
multi-omics data sources
kernel-based data integration
machine learning
cancer precision medicine
Engineering Prodrug Nanomedicine for Cancer Immunotherapy
期刊论文
ADVANCED SCIENCE, 2020, 页码: 33
作者:
Yang, Bin
;
Gao, Jing
;
Pei, Qing
;
Xu, Huixiong
;
Yu, Haijun
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/12/21
cancer immunotherapy
combination immunotherapy
nanomedicine
prodrugs
stimuli‐
responsive
Automated design and optimization of multitarget schizophrenia drug candidates by deep learning
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 204, 页码: 16
作者:
Tan, Xiaoqin
;
Jiang, Xiangrui
;
He, Yang
;
Zhong, Feisheng
;
Li, Xutong
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/12/21
Schizophrenia
Multitarget antipsychotic drugs
Recurrent neural network
Multitask deep neural network
Automated drug design
Smart Nanosized Drug Delivery Systems Inducing Immunogenic Cell Death for Combination with Cancer Immunotherapy
期刊论文
ACCOUNTS OF CHEMICAL RESEARCH, 2020, 卷号: 53, 期号: 9, 页码: 1761-1772
作者:
Zhou, Lei
;
Zhang, Pengcheng
;
Wang, Hao
;
Wang, Dangge
;
Li, Yaping
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/12/21
Drug Delivery System in the Treatment of Diabetes Mellitus
期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2020, 卷号: 8, 页码: 16
作者:
Zhao, Ruichen
;
Lu, Zhiguo
;
Yang, Jun
;
Zhang, Liqun
;
Li, Yan
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/10/30
diabetes mellitus
drug delivery
insulin
gene therapy
nanoparticle
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