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CORC

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Protective Role of mPGES-1 (Microsomal Prostaglandin E Synthase-1)-Derived PGE(2) (Prostaglandin E-2) and the Endothelial EP4 (Prostaglandin E Receptor) in Vascular Responses to Injury 期刊论文
2018, 卷号: 38, 期号: 5, 页码: 1115-1124
作者:  Hao, Huifeng;  Hu, Sheng;  Wan, Qing;  Xu, Chuansheng;  Chen, Hong
收藏  |  浏览/下载：9/0  |  提交时间：2020/01/03
Stauntoside B inhibits macrophage activation by inhibiting NF-κB and ERK MAPK signalling 期刊论文
Pharmacological Research, 2016, 卷号: 111, 期号: Volume 111, 页码: 303-315
作者:  Liu, Jianxin;  Tang, Jinshan;  Zuo, Yihan;  Yu, Yang;  Luo, Pei
收藏  |  浏览/下载：19/0  |  提交时间：2019/12/03
NO  nitric oxide  PGE2  prostaglandin E2  NSAIDs  non-steroidal anti-inflammatory drugs  qRT-PCR  quantitative real-time polymerase chain reaction  LPS  lipopolysaccharide  IFN-γ  interferon γ  G-CSF  granulocyte colony stimulating factor  TNF-α  tumor necrosis factor-α  IL-1β  interleukin-1β  IL-6  interleukin-6  MCP-1  monocyte chemoattractant protein-1  NF-κB  Nuclear factor-κB  IκB  inhibitory protein  IKK  IκB kinase  RPS3  ribosomal protein S3  iNOS  inducible nitric oxide synthase  COX-2  cyclooxygenase-2  PGESs  prostaglandin E2 synthases  mPGES-1  microsomal prostaglandin synthetase-1  mPGES-2  microsomal prostaglandin E synthase-2  cPGES  cytosolic prostaglandin E synthase  MAPK  mitogen-activated protein kinases  ERK  extracellular signal-regulated kinase  JNK  c- Jun N-terminal kinase  PGI2  prostacyclin I2  PGD2  prostaglandin D2  PGF2α  prostaglandin F2α  TXA2  thromboxane A2  Stauntoside B (PubChem CID: 101010462)  Stauntoside B  Cynanchi stauntonii  Lipopolysaccharide  Anti-inflammatory activity  NF-κB  MAPK  
Benzo[d] isothiazole 1,1-dioxide derivatives as dual functional inhibitors of 5-lipoxygenase and microsomal prostaglandin E-2 synthase-1 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 12, 页码: 2764-2767
作者:  Shang, Erchang;  Wu, Yiran;  Liu, Pei;  Liu, Ying;  Zhu, Wei
收藏  |  浏览/下载：10/0  |  提交时间：2019/04/09
Benzo[d] isothiazole 1,1-dioxide derivatives as dual functional inhibitors of 5-lipoxygenase and microsomal prostaglandin E-2 synthase-1 期刊论文
生物有机化学与医药化学通讯, 2014
Shang, Erchang; Wu, Yiran; Liu, Pei; Liu, Ying; Zhu, Wei; Deng, Xiaobing; He, Chong; He, Shan; Li, Cong; Lai, Luhua
收藏  |  浏览/下载：5/0  |  提交时间：2015/11/10
Microsomal Prostaglandin E Synthase-1 Deficiency Exacerbates Pulmonary Fibrosis Induced by Bleomycin in Mice 期刊论文
2014, 卷号: 19, 期号: 4, 页码: 4967-4985
作者:  Wei, Bo;  Cai, Linhong;  Sun, Dan;  Wang, Yanhua;  Wang, Cairui
收藏  |  浏览/下载：3/0  |  提交时间：2020/01/13
Kruppel-like Factor 5 Transcription Factor Promotes Microsomal Prostaglandin E-2 Synthase 1 Gene Transcription in Breast Cancer 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 卷号: 288, 期号: 37
作者:  Xia, Houjun;  Wang, Chunyan;  Chen, Wenlin;  Zhang, Hailin;  Chaudhury, Leena
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/04
Discovery of Highly Potent Microsomal Prostaglandin E-2 Synthase 1 Inhibitors Using the Active Conformation Structural Model and Virtual Screen 期刊论文
journal of medicinal chemistry, 2013
He, Shan; Li, Cong; Liu, Ying; Lai, Luhua
收藏  |  浏览/下载：4/0  |  提交时间：2015/11/10
Kruppel-like Factor 5 Transcription Factor Promotes Microsomal Prostaglandin E-2 Synthase 1 Gene Transcription in Breast Cancer 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2013, 卷号: 288, 期号: 37, 页码: 26731-26740
作者:  Xia HJ;  Wang CY;  Chen WL;  Zhang HL;  Chaudhury L
收藏  |  浏览/下载：10/0  |  提交时间：2014/10/22
Dynamic Modeling of Human 5-Lipoxygenase-Inhibitor Interactions Helps To Discover Novel Inhibitors 期刊论文
journal of medicinal chemistry, 2012
Wu, Yiran; He, Chong; Gao, Yang; He, Shan; Liu, Ying; Lai, Luhua
收藏  |  浏览/下载：5/0  |  提交时间：2015/11/13
Microsomal prostaglandin E synthase-1 exhibits one-third-of-the-sites reactivity 期刊论文
biochemical journal, 2011
He, Shan; Wu, Yiran; Yu, Daqi; Lai, Luhua
收藏  |  浏览/下载：4/0  |  提交时间：2015/11/13

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