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昆明植物研究所 [12]
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Precise Structure and Anticoagulant Activity of Fucosylated Glycosaminoglycan from Apostichopus japonicus: Analysis of Its Depolymerized Fragments
期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 4, 页码: 13
作者:
Guan, Ruowei
;
Peng, Yuan
;
Zhou, Lutan
;
Zheng, Wenqi
;
Liu, Xixi
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2019/06/24
Apostichopus japonicus
fucosylated glycosaminoglycan
oligosaccharide
unambiguous structure
anti-Fxase
Optimization of P2Y(12) Antagonist Ethyl 6-(4-((Benzylsulfonyl)carbarnoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate (AZD1283) Led to the Discovery of an Oral Antiplatelet Agent with Improved Druglike Properties
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 3088-3106
作者:
Kong, Deyu
;
Xue, Tao
;
Guo, Bin
;
Cheng, Jianjun
;
Liu, Shunyin
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  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
Prediction of Ticagrelor and its Active Metabolite in Liver Cirrhosis Populations Using a Physiologically Based Pharmacokinetic Model Involving Pharmacodynamics
期刊论文
JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 108, 期号: 8
作者:
Zhang, Min
;
You, Xiang
;
Ke, Meng
;
Jiao, Zheng
;
Wu, Hongwei
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/05
ticagrelor
active metabolite
physiologically based pharmacokineticmodel
liver cirrhosis populations
inhibition of platelet aggregation
Design, synthesis, and biological evaluation of 2-(phenoxyaryl)-3-urea derivatives as novel P2Y(1) receptor antagonists
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 302-310
作者:
Peng, Jingjing
;
Zhao, Lifen
;
Wang, Lanlan
;
Chen, Hui
;
Qiu, Yunguang
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  |  
浏览/下载:47/0
  |  
提交时间:2019/01/08
P2Y(1) receptor antagonist
2-(phenoxyaryl)-3-urea derivatives
Anti-Platelet
Evaluation of Tolerability, Pharmacokinetics and Pharmacodynamics of Vicagrel, a Novel P2Y12 Antagonist, in Healthy Chinese Volunteers
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Li, Xiaojiao
;
Liu, Ca
;
Zhu, Xiaoxue
;
Wei, Haijing
;
Zhang, Hong
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2019/01/08
vicagrel
pharmacokinetics
pharmacodynamics
safety
clopidogrel
Small size fullerenol nanoparticles inhibit thrombosis and blood coagulation through inhibiting activities of thrombin and fxa
期刊论文
Nanomedicine-nanotechnology biology and medicine, 2018, 卷号: 14, 期号: 3, 页码: 929-939
作者:
Xia, Shibo
;
Li, Juan
;
Zu, Mian
;
Li, Jinxia
;
Liu, Jinke
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2019/04/23
Fullerenols
Anticoagulation
Thrombin
Fxa
Ca2+
Inhibition of thrombosis
NIR-Triggered Release of Nitric Oxide with Upconversion Nanoparticles Inhibits Platelet Aggregation in Blood Samples
期刊论文
PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION, 2018, 卷号: 35, 期号: 2
作者:
Li, Chenxi
;
Shen, Jianwei
;
Yang, Jianfeng
;
Yan, Jun
;
Yu, Haijun
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
gaseous signaling molecules
NIR-triggered reaction
nitric oxide release
platelet aggregation
upconversion nanoparticles
Synthesis, nitric oxide release, and dipeptidyl peptidase-4 inhibition of sitagliptin derivatives as new multifunctional antidiabetic agents.
期刊论文
Bioorganic & medicinal chemistry letters, 2018, 卷号: 28, 页码: 3731-3735
作者:
Xie Yundong
;
Shao Lihua
;
Wang Qiutang
;
Bai Yue
;
Chen Zizhang
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/11/26
Anti-platelet aggregation
Antioxidant
Dipeptidyl peptidase IV
Hypoglycemic
Nitric oxide
Sitagliptin derivatives
Small size fullerenol nanoparticles inhibit thrombosis and blood coagulation through inhibiting activities of thrombin and FXa
期刊论文
NANOMEDICINE: NANOTECHNOLOGY, BIOLOGY AND MEDICINE, 2018, 卷号: 14, 期号: 3, 页码: 929-939
作者:
Li, JX
;
Xing GM(邢更妹)
;
Zhao LN(赵丽娜)
;
Gu WH(古伟宏)
;
Chen K(陈奎)
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/09/24
Fullerenols
Anticoagulation
Thrombin
FXa
Ca2+
Inhibition of thrombosis
Synthesis, nitric oxide release, and dipeptidyl peptidase-4 inhibition of sitagliptin derivatives as new multifunctional antidiabetic agents.
期刊论文
2018
作者:
Xie Yundong
;
Shao Lihua
;
Wang Qiutang
;
Bai Yue
;
Chen Zizhang
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/04/15
Anti-platelet
aggregation
Antioxidant
Dipeptidyl
peptidase
IV
Hypoglycemic
Nitric
oxide
Sitagliptin
derivatives
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