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Zinc oxide/graphene oxide nanocomposites efficiently inhibited cadmium-induced hepatotoxicity via releasing Zn ions and up-regulating MRP1 expression
期刊论文
ENVIRONMENT INTERNATIONAL, 2022, 卷号: 165
作者:
Liu, Yun
;
Wang, Xue
;
Si, Bo
;
Wang, Tong
;
Wu, Yun
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/12/23
Cadmium
Zinc oxide
Graphene oxide
Detoxification
Bioaccumulation
Magnetic resonance imaging
Nano-selenium attenuates mitochondrial-associated apoptosis via the PI3K/AKT pathway in nickel-induced hepatotoxicity in vivo and in vitro
期刊论文
ENVIRONMENTAL TOXICOLOGY, 2021
作者:
Wang, Caixia
;
Gu, Zhangyu
;
Gu, Xueyan
;
Tan, Xinyue
;
Wang, Shuang
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2021/11/01
hepatotoxicity
mitochondrial apoptosis
Nano-Se
nickel
PI3K-Akt pathway
Emerging health risks and underlying toxicological mechanisms of uranium contamination: Lessons from the past two decades
期刊论文
ENVIRONMENT INTERNATIONAL, 2020, 卷号: 145, 页码: 1-9
作者:
Ma, Minghao
;
Wang, Ruixia
;
Xu, Lining
;
Xu, Ming
;
Liu, Sijin
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/09/14
Uranium contamination
Human exposure
Health risk
Chemotoxicity
Toxicological mechanism
Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP)
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2020, 卷号: 205, 页码: 9
作者:
Wang, Xiaoqing
;
Li, Fei
;
Liu, Jialin
;
Ji, Chenglong
;
Wu, Huifeng
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/06/21
Triphenyl phosphate (TPP)
Multi-omit approach
Hepatotoxicity
Comprehensive analysis of transcriptomics and metabolomics to understand triptolide-induced liver injury in mice
期刊论文
TOXICOLOGY LETTERS, 2020, 卷号: 333, 页码: 290-302
作者:
Zhao, Jie
;
Xie, Cen
;
Wang, Kanglong
;
Takahashi, Shogo
;
Krausz, Kristopher W.
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/12/21
Triptolide
Transcriptomics
Metabolomics
Apoptosis
Acylcarnitine
Liver toxicity of macrolide antibiotics in zebrafish
期刊论文
TOXICOLOGY, 2020, 卷号: 441, 页码: 12
作者:
Zhang, Miao-qing
;
Chen, Bo
;
Zhang, Jing-pu
;
Chen, Ning
;
Liu, Chun-zhao
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/09/22
Liver toxicity
Macrolides
ADMET
RNA-seq analysis
Differentially expressed genes
c-Fos
Protein target identification and toxicological mechanism investigation of silver nanoparticles-induced hepatotoxicity by integrating proteomic and metallomic strategies
期刊论文
PARTICLE AND FIBRE TOXICOLOGY, 2019, 卷号: 16, 期号: 1, 页码: -
作者:
Xu, Ming
;
Yang, Qiuyuan
;
Xu, Lining
;
Rao, Ziyu
;
Cao, Dong
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/09/10
Silver nanoparticles
Silver ion
Hepatotoxicity
Protein target
Glutathione S-transferase
Intestinal and hepatic biotransformation of pyrrolizidine alkaloid N-oxides to toxic pyrrolizidine alkaloids
期刊论文
ARCHIVES OF TOXICOLOGY, 2019, 卷号: 93, 期号: 8, 页码: 2197-2209
作者:
Yang, Mengbi
;
Ma, Jiang
;
Ruan, Jianqing
;
Ye, Yang
;
Fu, Peter Pi-Cheng
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
Pyrrolizidine alkaloid N-oxides
Pyrrolizidine alkaloids
Pyrrolizidine alkaloid N-oxide toxicity
Biotransformation of pyrrolizidine alkaloid N-oxides
Microbiota biotransformation
Herb-Induced Liver Injury: Phylogenetic Relationship, Structure-Toxicity Relationship, and Herb-Ingredient Network Analysis
期刊论文
2019, 卷号: 20, 期号: 15
作者:
He Shuaibing
;
Zhang Chenyang
;
Zhou Ping
;
Zhang Xuelian
;
Ye Tianyuan
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/01/03
HILI
hepatotoxicity
herb
herb-ingredient network
mechanism
phylogenetic tree
structure-toxicity relationship
In silico Identification and Mechanism Exploration of Hepatotoxic Ingredients in Traditional Chinese Medicine
期刊论文
2019, 卷号: 10, 页码: 458
作者:
Wu, Qihui
;
Cai, Chuipu
;
Guo, Pengfei
;
Chen, Meiling
;
Wu, Xiaoqin
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/01/03
herb induced liver injury
consensus model
traditional chinese medicine
hepatotoxicity mechanism
in silico
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