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Valeriana jatamansi Jones ex Roxb. Against Post-Traumatic Stress Disorder, Network Pharmacological Analysis, and In Vivo Evaluation
期刊论文
FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12, 页码: 19
作者:
Yang, Xue
;
Guo, Jian-You
;
Jiang, Ya-Ni
;
Liu, Meng-Meng
;
Li, Qiu-Yu
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2022/02/11
Valeriana jatamansi Jones ex Roxb
post-traumatic stress disorder
network pharmacology
neurotransmitters
HPA
endocannabinoid system
Inhibition of Fatty Acid Amide Hydrolase Improves Depressive-Like Behaviors Independent of Its Peripheral Antinociceptive Effects in a Rat Model of Neuropathic Pain
期刊论文
ANESTHESIA AND ANALGESIA, 2019, 卷号: 129, 期号: 2
作者:
Jiang, Hai-xia
;
Ke, Bo-wen
;
Liu, Jin
;
Ma, Gang
;
Hai, Ke-rong
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  |  
浏览/下载:20/0
  |  
提交时间:2019/12/04
内源性大麻素系统介导非阿片类安慰剂镇痛效应在炎性痛中的机制研究
学位论文
中国科学院心理研究所: 中国科学院心理研究所, 2018
作者:
顾丽佳
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  |  
浏览/下载:42/0
  |  
提交时间:2019/12/23
非阿片
安慰剂镇痛
大麻素受体
前边缘皮层
伏隔核
Elevation of arachidonoylethanolamide levels by activation of the endocannabinoid system protects against colitis and ameliorates remote organ lesions in mice
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2017, 卷号: 14, 期号: 6
作者:
Zhao, Xiaolin
;
Liang, Peng
;
Liu, Jin
;
Jiang, Haixia
;
Fan, Xiaoshuai
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/04
URB597
fatty acid amide hydrolase
endocannabinoid system
colitis
blood-brain-barrier integrity
Molecular mechanisms involved in the side effects of fatty acid amide hydrolase inhibitors: a structural phenomics approach to proteome-wide cellular off-target deconvolution and disease association.
期刊论文
NPJ systems biology and applications, 2016, 卷号: 2
作者:
Dider, Shihab
;
Ji, Jiadong
;
Zhao, Zheng
;
Xie, Lei
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  |  
浏览/下载:8/0
  |  
提交时间:2019/12/17
Docosahexaenoyl serotonin, an endogenously formed n-3 fatty acid-serotonin conjugate has anti-inflammatory properties by attenuating IL-23–IL-17 signaling in macrophages
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2016, 卷号: 1861, 期号: 12, 页码: 2020-2028
作者:
Poland, Mieke
;
ten Klooster, Jean Paul
;
Wang, Zheng
;
Pieters, Raymond
;
Boekschoten, Mark
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  |  
浏览/下载:9/0
  |  
提交时间:2019/12/23
AA-5-HT
arachidonoyl serotonin
AEA
arachidonoyl ethanolamide (anandamide)
COX-2
cyclooxygenase 2
DHA
docosahexaenoic acid (22:6n-3)
DHA-5-HT
docosahexaenoyl serotonin
DHEA
docosahexaenoyl ethanolamine
EPA-5-HT
eicosapentaenoyl serotonin
FAA
fatty acid amides
FAAH
fatty acid amide hydrolase
FDR
false discovery rate
GSEA
gene-set enrichment analysis
IL
Interleukin
n-3 LC PUFA
(n-3) long chain polyunsaturated fatty acid
LPS
lipopolysaccharide
NO
nitric oxide
NOS2
nitric oxide synthase 2
NES
normalized Enrichment Score
OA-5-HT
oleoyl serotonin
OEA
oleoyl ethanolamine
PA-5-HT
palmitoyl serotonin
TRPV1
transient receptor potential channel type V1
Acyl serotonines
DHA
DHA-5-HT
Nrf2
Intestine
Endocannabinoids
新型脂肪酰胺水解酶抑制剂的设计、合成和活性评价
学位论文
2015, 2013
王中奎
收藏
  |  
浏览/下载:129/0
  |  
提交时间:2016/02/23
虚拟筛选
FAAH抑制剂合成
FAAH酶活性测试
virtual screening
synthesis of FAAH inhibitors
FAAH enzyme activity test
Structural and energetic insights into the selective interactions of monoacylglycerol lipase with its natural substrate and small-molecule inhibitors
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2014, 卷号: 23, 期号: 5, 页码: 2391-2404
作者:
Chen, Huayou
;
Sun, Tengyun
;
Chen, Hongzhang
;
Tian, Rui
;
Zhang, Tianxi
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2014/05/06
Monoacylglycerol lipase
Fatty acid amide hydrolase
Inhibitor selectivity
Quantum mechanics/molecular mechanics
Quantitative structure-selectivity relationship
Alteration of endocannabinoid system in human gliomas
期刊论文
http://dx.doi.org/10.1111/j.1471-4159.2011.07625.x, 2012
Wu, Xiyue
;
Han, Lijun
;
Zhang, Xiaolin
;
Li, Long
;
Jiang, Changzhen
;
Qiu, Yan
;
Huang, Rui
;
Xie, Baoying
;
Lin, ZhiXiong
;
Ren, Jie
;
Fu, Jin
;
邱彦
;
任杰
;
傅瑾
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2015/07/22
CANCER CELL-PROLIFERATION
CB2 RECEPTOR EXPRESSION
CANNABINOID RECEPTOR
ENDOGENOUS CANNABINOIDS
N-ACYLETHANOLAMINES
MALIGNANT GLIOMAS
BRAIN-TISSUE
HUMAN BREAST
IN-VIVO
ANANDAMIDE
A novel indole alkaloid from deep-sea sediment metagenomic clone-derived Escherichia coli fermentation broth
期刊论文
http://dx.doi.org/10.1080/10286020.2011.570262, 2011
Chen, Lin
;
Tang, Xi-Xiang
;
Zheng, Min
;
Yi, Zhi-Wei
;
Xiao, Xiang
;
Qiu, Ying-Kun
;
Wu, Zhen
;
陈亮
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2013/12/12
deep-sea sediment
metagenomic clone
N-{1-[4-(acetylamino)phenyl]-3-hydroxy-1-(1H-indol-3-yl)propan-2-yl}-2
2-dichloroacetamide
indole alkaloids
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