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科研机构
厦门大学 [2]
中南大学 [2]
上海药物研究所 [1]
心理研究所 [1]
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期刊论文 [6]
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2019 [1]
2017 [1]
2016 [1]
2012 [1]
2010 [1]
2009 [1]
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Caffeic acid reduces A53T alpha-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse model of Parkinson's disease
期刊论文
PHARMACOLOGICAL RESEARCH, 2019, 卷号: 150, 页码: 14
作者:
Zhang, Yu
;
Wu, Qimei
;
Zhang, Lei
;
Wang, Qing
;
Yang, Zexian
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
Caffeic acid
A53T
Parkinson's disease
Autophagy
JNK
Altered Functional Brain Connectomes between Sporadic and Familial Parkinson's Patients.
期刊论文
Frontiers in Neuroanatomy, 2017, 卷号: 11, 页码: 99
作者:
Tang, Yan
;
Xiao, Xue
;
Xie, Hua
;
Wan, Chang-min
;
Meng, Li
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
assortativity
familial PD
functional brain connectome
small-worldness
sporadic PD
Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson's disease
期刊论文
PROTEIN & CELL, 2016, 卷号: 7, 期号: 2, 页码: 114-129
作者:
Song, Pingping
;
Li, Shanshan
;
Wu, Hao
;
Gao, Ruize
;
Rao, Guanhua
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2016/05/09
parkin
sequestosome1/p62
ubiquitin
substantia nigra
Leucine-rich repeat kinase 2 inhibitors: a patent review (2006-2011)
期刊论文
http://dx.doi.org/10.1517/13543776.2012.729041, 2012
Deng, Xianming
;
Choi, Hwan Geun
;
Buhrlage, Sara J.
;
Gray, Nathanael S.
;
邓贤明
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2015/07/22
DISEASE-ASSOCIATED MUTATIONS
PARKINSONS-DISEASE
CYTOPLASMIC LOCALIZATION
ANGIOGENESIS INHIBITOR
14-3-3 BINDING
PHASE-I
LRRK2
POTENT
SELECTIVITY
DISCOVERY
R492X mutation in PTEN-induced putative kinase 1 induced cellular mitochondrial dysfunction and oxidative stress
期刊论文
Brain Research, 2010, 卷号: 1351, 页码: 229-237
作者:
Yuan, Xiang-li
;
Guo, Ji-feng
;
Shi, Zhen-hua
;
Xiao, Zhi-qian
;
Yan, Xin-xiang
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
PD
Parkinson's disease
PINK1
PTEN-induced putative kinase 1
ROS
reactive oxidative species
Cyt.C
cytochrome C
MPP+
Methyl-4-phenylpyridinium ion
FPD
familial forms of Parkinson's disease
DMEM
Dulbecco's modified Eagle's medium
FBS
fetal calf serum
DMSO
dimethyl sulfoxide
DCIP
2,6-dichloroindophenol
DCFH-DA
2′7′-dicholorodihydrofluorescein diacetate
FITC
fluorescein isothiocyanate
Parkinson's disease (PD)
Reactive oxidative species (ROS)
Mitochondria
PTEN-induced putative kinase 1 (PINK1)
FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation
期刊论文
2009
Mei, Yang
;
梅杨
;
Zhang, Yiru
;
张毅汝
;
Yamamoto, Kazuo( Princess Margaret Hosp, Campbell Family Inst Breast Canc Res, Toronto)
;
Xie, Wei
;
Mak, Tak W.( Princess Margaret Hosp, Campbell Family Inst Breast Canc Res, Toronto)
;
You, Han
;
尤涵
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2011/12/06
apoptosis
oxidative stress
transcription
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