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E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2
期刊论文
EMBO REPORTS, 2022
作者:
Li, Hui
;
Wang, Ning
;
Jiang, Yu
;
Wang, Haofei
;
Xin, Zengfeng
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/12/22
IL-17R signaling
inflammation
MEKK2
NEDD4L
ubiquitination
Cytoplasmic DNA sensing by KU complex in aged CD4(+) T cell potentiates T cell activation and aging-related autoimmune inflammation
期刊论文
IMMUNITY, 2021, 卷号: 54, 期号: 4, 页码: 632-+
作者:
Wang, Yan
;
Fu, Zunyun
;
Li, Xutong
;
Liang, Yinming
;
Pei, Siyu
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/06/11
9,10-Anhydrodehydroartemisinin Attenuates Experimental Autoimmune Encephalomyelitis by Inhibiting Th1 and Th17 Cell Differentiation
期刊论文
INFLAMMATION, 2021, 页码: 10
作者:
Lv, Jie
;
Zhuang, Wei
;
Zhang, Yan
;
Xie, Ling
;
Xiang, Zhenglong
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/05/24
9
10-Anhydrodehydroartemisinin
artemisinin
multiple sclerosis
Th1
Th17
experimental autoimmune encephalomyelitis
Natural product piperine alleviates experimental allergic encephalomyelitis in mice by targeting dihydroorotate dehydrogenase
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 15
作者:
Liu, Zehui
;
Hu, Qian
;
Wang, Wanyan
;
Lu, Sisi
;
Wu, Dang
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/12/24
Multiple sclerosis
DHODH
Piperine
Natural product
Vaccines targeting the primary amino acid sequence and conformational epitope of amyloid-beta had distinct effects on neuropathology and cognitive deficits in EAE/AD mice
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 页码: 12
作者:
Yu, Xiao-Lin
;
Zhu, Jie
;
Liu, Xiang-meng
;
Xu, Peng-xin
;
Zhang, Yue
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/05/21
The PD-1/PD-Ls pathway is up-regulated during the suppression of experimental autoimmune encephalomyelitis treated by Astragalus polysaccharides
期刊论文
JOURNAL OF NEUROIMMUNOLOGY, 2019, 卷号: 332
作者:
Sun, Yu
;
Jing, Yuanya
;
Huang, Mengwen
;
Ma, Jinyun
;
Peng, Xiaoyan
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/05
PD-1/PD-Ls molecules
EAE
CNS
T lymphocytes
Astragalus polysaccharides
The PD-1/PD-Ls pathway is up-regulated during the suppression of experimental autoimmune encephalomyelitis treated by Astragalus polysaccharides
期刊论文
Journal of neuroimmunology, 2019, 卷号: 332, 页码: 78-90
作者:
Sun Yu[1]
;
Jing Yuanya[2]
;
Huang Mengwen[3]
;
Ma Jinyun[4]
;
Peng Xiaoyan[5]
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/04/22
Astragalus polysaccharides
CNS
EAE
PD-1/PD-Ls molecules
T lymphocytes
p38MAPK/SGK1 signaling regulates macrophage polarization in experimental autoimmune encephalomyelitis
期刊论文
AGING-US, 2019, 卷号: 11, 期号: 3, 页码: 898-907
作者:
Li, Bo
;
Tan, Tian-Bi
;
Wang, Liang
;
Zhao, Xiao-Yun
;
Tan, Guo-Jun
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
multiple sclerosis (MS)
experimental autoimmune encephalomyelitis
(EAE)
macrophage polarization
p38MAPK/SGK1 signaling
Astragaloside IV regulates differentiation and induces apoptosis of activated CD4 T cells in the pathogenesis of experimental autoimmune encephalomyelitis
期刊论文
Toxicology and applied pharmacology, 2019, 卷号: 362, 页码: 105-115
作者:
Yang, Liu
;
Xing, Faping
;
Han, Xinyan
;
Li, Qi
;
Wu, Hui
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
N-Phenylquinazolin-2-amine Yhhu4952 as a novel promotor for oligodendrocyte differentiation and myelination
期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8
作者:
Yu, Xueli
;
Cheng, Gang
;
Zhang, Lei
;
Zhang, Yu
;
Wang, Qing
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2019/01/08
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