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An aggregation-induced emission fluorescence probe for evaluating the effect of CYP450 changes under tumor chemotherapy
期刊论文
TALANTA, 2022, 卷号: 239, 页码: 9
作者:
Lu, Pengpeng
;
Huang, Yan
;
Zhang, Caiyun
;
Fu, Lili
;
Wang, Xiaoyan
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/07/04
Cytochrome P450
Fluorescence imaging
Chemotherapy
Liver cancer
Evaluate the inhibition of cytochrome P450 1A1 for enhancing breast cancer chemotherapy with a turn-on fluorescent probe
期刊论文
SENSORS AND ACTUATORS B-CHEMICAL, 2021, 卷号: 344, 页码: 8
作者:
Huang, Yan
;
Yu, Lei
;
Lu, Pengpeng
;
Wei, Yinghui
;
Wang, Xiaoyan
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2021/10/21
Fluorescent probe
Chemotherapy
Breast cancer
Fluorescence imaging
Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439
期刊论文
ACS INFECTIOUS DISEASES, 2021, 卷号: 7, 期号: 7, 页码: 1885-1893
作者:
Shackleford, David M.
;
Chiu, Francis C. K.
;
Katneni, Kasiram
;
Blundell, Scott
;
McLaren, Jenna
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  |  
浏览/下载:59/0
  |  
提交时间:2021/11/04
OZ439 (artefenomel)
malaria
metabolite identification
cytochrome P450 metabolism
cytochrome P450 inhibition
time-dependent inhibition
Alflutinib (AST2818), primarily metabolized by CYP3A4, is a potent CYP3A4 inducer
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Liu, Xiao-yun
;
Guo, Zi-tao
;
Chen, Zhen-dong
;
Zhang, Yi-fan
;
Zhou, Jia-lan
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  |  
浏览/下载:76/0
  |  
提交时间:2020/07/01
alflutinib
AST5902
metabolism
enzyme induction
drug-drug interaction
The Nonclinical Pharmacokinetics and Prediction of Human Pharmacokinetics of SPH3127, a Novel Direct Renin Inhibitor
期刊论文
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 45, 期号: 1, 页码: 15-26
作者:
Zhang, Leduo
;
Mao, Yu
;
Gao, Zhiwei
;
Chen, Xiaoyan
;
Li, Xin
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  |  
浏览/下载:45/0
  |  
提交时间:2020/07/01
hUMSCs regulate the differentiation of ovarian stromal cells via TGF-β 1
期刊论文
Stem Cell Research & Therapy, 2020, 卷号: 11, 期号: 1
作者:
Linlu Cui
;
Hongchu Bao
;
Zhongfeng Liu
;
Xuejing Man
;
Hongyuan Liu
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/07
Intravenous formulation of Panax notoginseng root extract: human pharmacokinetics of ginsenosides and potential for perpetrating drug interactions
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1351-1363
作者:
Pintusophon, Salisa
;
Niu, Wei
;
Duan, Xiao-na
;
Olaleye, Olajide E.
;
Huang, Yu-hong
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  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
ginsenoside
cytochrome P450 3A
organic anion-transporting polypeptide 1B3
herbal medicine-drug interactions
XueShuanTong
Panax notoginseng
Nitrogen-doped graphene quantum dots (N-GQDs) perturb redox-sensitive system via the selective inhibition of antioxidant enzyme activities in zebrafish
期刊论文
BIOMATERIALS, 2019, 卷号: 206, 页码: 61-72
作者:
Deng, Shun
;
Fu, Ailing
;
Junaid, Muhammad
;
Wang, Yan
;
Yin, Qian
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2019/06/11
Danio rerio
N-GQDs
Redox system
Antioxidant enzyme activity
USGO
Induction of Cytochrome P450 Involved in the Accelerated Blood Clearance Phenomenon Induced by PEGylated Liposomes In Vivo
期刊论文
DRUG METABOLISM AND DISPOSITION, 2019, 卷号: 47, 期号: 4, 页码: 364-376
作者:
Wang, Fengling
;
Wu, Yifan
;
Zhang, Jiwen
;
Wang, Huihui
;
Xie, Xiaoting
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/07/01
Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 10
作者:
Ma, Hong-Ping
;
Dai, Zi-Ru
;
Ning, Jing
;
Sun, Gui-Bo
;
Wang, Ping
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2019/06/20
bufotalin
cytochrome P450 3A (CYP3A)
hydroxylation
human liver microsomes (HLMs)
docking simulations
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