CORC

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CORC

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Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:  Xu, Dandan;  Sun, Deqiao;  Wang, Wei;  Peng, Xia;  Zhan, Zhengsheng
收藏  |  浏览/下载：46/0  |  提交时间：2021/08/17
Discovery of a Pyrimidinedione Derivative as a Potent and Orally Bioavailable Axl Inhibitor 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 7, 页码: 3956-3975
作者:  Zhang, Hefeng;  Peng, Xia;  Dai, Yang;  Shao, Jingwei;  Ji, Yinchun
收藏  |  浏览/下载：16/0  |  提交时间：2021/06/11
Synthesis of triazolotriazine derivatives as c-Met inhibitors 期刊论文
MOLECULAR DIVERSITY, 2020, 页码: 8
作者:  Guo, Yuting;  Peng, Xia;  Ji, Yinchun;  Zhang, Yitong;  Ding, Jian
收藏  |  浏览/下载：37/0  |  提交时间：2020/12/24
SHR-A1403, a novel c-mesenchymal-epithelial transition factor (c-Met) antibody-drug conjugate, overcomes AZD9291 resistance in non-small cell lung cancer cells overexpressing c-Met 期刊论文
CANCER SCIENCE, 2019, 页码: 11
作者:  Tong, Mengya;  Gao, Mingzhao;  Xu, Yongping;  Fu, Li;  Li, Yun
收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01
SHR-A1403, a novel c-Met antibody-drug conjugate, exerts encouraging anti-tumor activity in c-Met-overexpressing models 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 7, 页码: 971-979
作者:  Yang, Chang-yong;  Wang, Lei;  Sun, Xing;  Tang, Mi;  Quan, Hai-tian
收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01
Discovery of a potent tyrosine kinase AXL inhibitor bearing the 3-((2,3,4,5-tetrahydro-1H-benzo [d] azepin-7-yl)amino)pyrazine core 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 6, 页码: 836-838
作者:  Wang, Yueliang;  Xing, Li;  Ji, Yinchun;  Ye, Jiqing;  Dai, Yang
收藏  |  浏览/下载：15/0  |  提交时间：2020/07/01
2,7-naphthyridinone-based MET kinase inhibitors: A promising novel scaffold for antitumor drug development 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 178, 页码: 705-714
作者:  Zhuo, Lin-Sheng;  Xu, Hong-Chuang;  Wang, Ming-Shu;  Zhao, Xing-E;  Ming, Zhi-Hui
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/23
Therapeutic activity of DCC-2036, a novel tyrosine kinase inhibitor, against triple-negative breast cancer patient-derived xenografts by targeting AXL/MET. 期刊论文
International Journal of Cancer, 2019, 卷号: 144, 期号: 3, 页码: 651-664
作者:  Shen, Yingying;  Zhang, Wei;  Liu, Jianghua;  He, Jun;  Cao, Renxian
收藏  |  浏览/下载：11/0  |  提交时间：2019/12/27
*AXL  *DCC-2036  *MET  *PDX  *TNBC  
Preclinical Evaluation of SCC244 (Glumetinib), a Novel, Potent, and Highly Selective Inhibitor of c-Met in MET-dependent Cancer Models 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2018, 卷号: 17, 期号: 4, 页码: 751-762
作者:  Ai, Jing;  Chen, Yi;  Peng, Xia;  Ji, Yinchun;  Xi, Yong
收藏  |  浏览/下载：50/0  |  提交时间：2019/01/08
The improved growth performance and enhanced immune function by DL-methionyl-DL-methionine are associated with NF-kappa B and TOR signalling in intestine of juvenile grass carp (Ctenopharyngodon idella) 期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2018, 卷号: 74, 期号: 1, 页码: 101-118
作者:  Su, Yue-Ning;  Wu, Pei;  Feng, Lin;  Jiang, Wei-Dan;  Jiang, Jun
收藏  |  浏览/下载：54/0  |  提交时间：2019/07/03

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