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上海神经科学研究所 [10]
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A bioactive gypenoside (GP-14) alleviates neuroinflammation and blood brain barrier (BBB) disruption by inhibiting the NF-κB signaling pathway in a mouse high-altitude cerebral edema (HACE) model
期刊论文
International Immunopharmacology, 2022, 期号: 107, 页码: 108675
作者:
Ya-Nan Geng
;
Jun-Li Yang
;
Xiang Cheng
;
Ying Han
;
Feng Yan
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2022/11/30
Gypenoside
Neuroinflammation
Blood brain barrier
High altitude cerebral edema
NF-κB signaling pathway
Intrathecal administration of the extracellular vesicles derived from human Wharton's jelly stem cells inhibit inflammation and attenuate the activity of inflammasome complexes after spinal cord injury in rats
期刊论文
NEUROSCIENCE RESEARCH, 2021, 卷号: 170, 页码: 87-98
作者:
Noori, Leila
;
Arabzadeh, Somayeh
;
Mohamadi, Yousef
;
Mojaverrostami, Sina
;
Mokhtari, Tahmineh
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/09/24
Spinal cord injury
Inflammasome
Wharton's jelly mesenchymal stem cells
Extracellular vesicles
Intrathecal injection
Development of Bisindole-Substituted Aminopyrazoles as Novel GSK-3 beta Inhibitors with Suppressive Effects against Microglial Inflammation and Oxidative Neurotoxicity
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2020, 卷号: 11, 期号: 20, 页码: 3398-3408
作者:
Liu, Jian-Guo
;
Zhao, Danfeng
;
Gong, Qi
;
Bao, Fengxia
;
Chen, Wen-Wen
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/05/24
Glycogen synthase kinase-3
bisindole-substituted aminopyrazoles
Alzheimer's disease
oxidative neurotoxicity
microglial inflammation
Brain-specific NRSF deficiency aggravates dopaminergic neurodegeneration ana impairs neurogenesis in the MPTP mouse model of Parkinson's disease
期刊论文
AGING-US, 2019, 卷号: 11, 期号: 10
作者:
Huang, Dongping
;
Li, Qing
;
Wang, Yi
;
Liu, Zhaolin
;
Wang, Zishan
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/05
Parkinson's disease
neurodegeneration
NRSF/REST
astrocyte activation
neuroinflammation
Losartan inhibits development of spontaneous recurrent seizures by preventing astrocyte activation and attenuating blood-brain barrier permeability following pilocarpine-induced status epilepticus
期刊论文
BRAIN RESEARCH BULLETIN, 2019, 卷号: 149
作者:
Sun Hong
;
He JianCheng
;
Wu JiaWen
;
Zhan ShuQin
;
Zhang GuiLian
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/05
Epilepsy
Astrocyte activation
Blood-brain barrier
Losartan
AQP4
TRPV1 mediates astrocyte activation and interleukin-1 release induced by hypoxic ischemia (HI)
期刊论文
JOURNAL OF NEUROINFLAMMATION, 2019, 卷号: 16
作者:
Yang, Xing-Liang
;
Wang, Xin
;
Shao, Lin
;
Jiang, Guang-Tong
;
Min, Jia-Wei
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  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
HI
Astrocyte
TRPV1
IL-1 beta
Inhibition of microRNA-103a inhibits the activation of astrocytes in hippocampus tissues and improves the pathological injury of neurons of epilepsy rats by regulating BDNF
期刊论文
CANCER CELL INTERNATIONAL, 2019, 卷号: 19
作者:
Zheng, Ping
;
Bin, He
;
Chen, Wei
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/06
Epilepsy
MicroRNA-103a
BDNF
Astrocyte
Hippocampal neurons
Inflammatory lesions
GFAP
Transmission electron microscope
The c-Jun N-terminal kinase signaling pathway in epilepsy: activation, regulation, and therapeutics
期刊论文
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, 2018, 卷号: 38, 期号: 5-6
作者:
Zhang, Wuqiong
;
Meng, Hongmei
;
Li, Jia-Ai
;
Yu, Miaomiao
;
Wang, Xue
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
c-Jun NH2-terminal kinase pathway
epilepsy
neuronal death
mossy fiber sprouting
astrocyte activation
A model of neuropathic pain in brachial plexus avulsion injury and associated spinal glial cell activation
期刊论文
JOURNAL OF PAIN RESEARCH, 2018, 卷号: 11
作者:
Hou, Ao-Lin
;
Xu, Wen-Dong
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
neuropathic pain
new model
astrocyte
microglia
Protective effects of Progranulin against focal cerebral ischemia-reperfusion injury in rats by suppressing endoplasmic reticulum stress and NF-kappa B activation in reactive astrocytes
期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2018, 卷号: 119, 页码: 6584-6597
作者:
Shu, Qing
;
Fan, Hua
;
Li, Shi-Jun
;
Zhou, Dan
;
Ma, Wei
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/11/26
Endoplasmic reticulum (ER) stress
progranulin (PGRN)
nuclear factor kappa B
astrocyte
focal cerebral ischemia-reperfusion
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