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CORC

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Subtypes of depression characterized by different cognitive decline and brain activity alterations 期刊论文
JOURNAL OF PSYCHIATRIC RESEARCH, 2021, 卷号: 138, 页码: 413-419
作者:  Yang, Xiao;  Qi, Shile;  Wang, Min;  Calhoun, Vince D.;  Sui, Jing
收藏  |  浏览/下载：36/0  |  提交时间：2021/08/15
Structural insights into the human D1 and D2 dopamine receptor signaling complexes 期刊论文
CELL, 2021, 卷号: 184, 期号: 4, 页码: 931-+
作者:  Zhuang, Youwen;  Xu, Peiyu;  Mao, Chunyou
收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24
Elevated serum anti-NMDA receptor antibody levels in first-episode patients with schizophrenia 期刊论文
Brain, Behavior, and Immunity, 2019, 卷号: Vol.81, 页码: 213-219
作者:  Tong J.;  Huang J.;  Luo X.;  Chen S.;  Cui Y.
收藏  |  浏览/下载：1/0  |  提交时间：2019/11/21
Design and optimization of purine derivatives as in vivo active PDE10A inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 13, 页码: 3315-3329
作者:  Chen, Liu;  Chen, Danqi;  Tang, Le;  Ren, Jing;  Chen, Jiaojiao
收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08
The effects of working memory training on enhancing hedonic processing to affective rewards in individuals with high social anhedonia 期刊论文
PSYCHIATRY RESEARCH, 2016, 卷号: 245, 期号: 0, 页码: 482-490
作者:  Li, Xu;  Xiao, Ya-Hui;  Zou, Lai-Quan;  Li, Huan-Huan;  Yang, Zhuo-Ya
收藏  |  浏览/下载：33/0  |  提交时间：2016/12/12
精神分裂症心理时间之旅的干预研究 学位论文
硕士, 北京: 中国科学院研究生院, 2016
作者:  陈桂芳
收藏  |  浏览/下载：70/0  |  提交时间：2016/06/27
4-7岁儿童叙事连贯性与衔接性的发展 学位论文
硕士, 北京: 中国科学院研究生院, 2016
作者:  曹轶娟
收藏  |  浏览/下载：108/0  |  提交时间：2016/06/27
The Impact of MIR137 on Dorsolateral Prefrontal-Hippocampal Functional Connectivity in Healthy Subjects 期刊论文
NEUROPSYCHOPHARMACOLOGY, 2014, 卷号: 39, 期号: 9, 页码: 2153-2160
作者:  Liu, Bing;  Zhang, Xiaolong;  Hou, Bing;  Li, Jin;  Qiu, Chengxiang
收藏  |  浏览/下载：20/0  |  提交时间：2015/08/12
Dual Ligands Targeting Dopamine D-2 and Serotonin 5-HT1A Receptors as New Antipsychotical or Anti-Parkinsonian Agents 期刊论文
CURRENT MEDICINAL CHEMISTRY, 2014, 卷号: 21, 期号: 4, 页码: 437-457
作者:  Ye, Na;  Song, Zilan;  Zhang, Ao
收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08
Profile of minocycline and its potential in the treatment of schizophrenia 期刊论文
Neuropsychiatric Disease and Treatment, 2014, 卷号: 10, 页码: 1103-1111
作者:  Zhang, Lulu;  Zhao, Jingping*
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/03
Accumulating evidence suggests that neuroinflammation affecting microglia plays an important role in the etiology of schizophrenia  and appropriate control of microglial activation may be a promising therapeutic strategy for schizophrenia. Minocycline  a second-generation tetracycline that inhibits microglial activation  has been shown to have a neuroprotective effect in various models of neurodegenerative disease  including anti-inflammatory  antioxidant  and antiapoptotic properties  and an ability to modulate glutamate-induced excitotoxicity. Given that these mechanisms overlap with neuropathologic pathways  minocycline may have a potential role in the adjuvant treatment of schizophrenia  and improve its negative symptoms. Here  we review the relevant studies of minocycline  ranging from preclinical research to human clinical trials.  

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