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浏览/检索结果: 共5条，第1-5条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy 期刊论文 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13 作者:  Hua, Chen;  Shena, Lijuan;  Zoua, Fengming;  Wua, Yun;  Wanga, Beilei 收藏  |  浏览/下载：10/0  |  提交时间：2023/11/10 Acquired resistance mutations  CDK9 inhibitors  Transcription  Single nucleotide polymorphisms  BAY1251152   Structural insight into multistage inhibition of CRISPR-Cas12a by AcrVA4 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 卷号: 116, 期号: 38 作者:  Peng, Ruchao;  Li, Zhiteng;  Xu, Ying;  He, Shaoshuai;  Peng, Qi 收藏  |  浏览/下载：22/0  |  提交时间：2019/12/05 CRISPR-Cas system  anti-CRISPR proteins  Cas12a  AcrVA4  inhibition mechanism   Anti-CRISPRdb: a comprehensive online resource for anti-CRISPR proteins 期刊论文 Nucleic Acids Research, 2018, 卷号: 46, 期号: D1, 页码: D393-D398 作者:  Dong, Chuan;  Hao, Ge-Fei;  Hua, Hong-Li;  Liu, Shuo;  Labena, Abraham Alemayehu 收藏  |  浏览/下载：10/0  |  提交时间：2019/12/23 bacteria   Alternate binding modes of anti-CRISPR viral suppressors AcrF1/2 to Csy surveillance complex revealed by cryo-EM structures 期刊论文 CELL RESEARCH, 2017 Peng, Ruchao; Xu, Ying; Zhu, Tengfei; Li, Ningning; Qi, Jianxun; Chai, Yan; Wu, Min; Zhang, Xinzheng; Shi, Yi; Wang, Peiyi; Wang, Jiawei; Gao, Ning; Gao, George Fu 收藏  |  浏览/下载：6/0  |  提交时间：2017/12/03 CRISPR/Cas system  anti-CRISPR proteins  phage  immune evasion  cryo-EM  BACTERIAL IMMUNE-SYSTEM  VIBRIO-PARAHAEMOLYTICUS  BACTERIOPHAGE THERAPY  ELECTRON-MICROSCOPY  ESCHERICHIA-COLI  CAS SYSTEMS  DNA  MECHANISMS  CASCADE  CRYSTALLOGRAPHY   The recombined cccDNA produced using minicircle technology mimicked HBV genome in structure and function closely 期刊论文 SCIENTIFIC REPORTS, 2016 作者:  Guo, Xiaoyan;  Chen, Ping;  Hou, Xiaohu;  Xu, Wenjuan;  Wang, Dan 收藏  |  浏览/下载：37/0  |  提交时间：2017/01/16