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科研机构
大连化学物理研究所 [12]
上海药物研究所 [4]
深圳先进技术研究院 [1]
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期刊论文 [16]
会议论文 [1]
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2018 [3]
2015 [2]
2014 [1]
2013 [2]
2012 [4]
2010 [4]
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物理化学 [3]
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New Insights into SN-38 Glucuronidation: Evidence for the Important Role of UDP Glucuronosyltransferase 1A9
期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2018, 卷号: 122, 期号: 4, 页码: 424-428
作者:
Xiao, Ling
;
Zhu, Liangliang
;
Li, Wenjuan
;
Li, Conghu
;
Cao, Yunfeng
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/06/20
Amentoflavone is a potent broad-spectrum inhibitor of human UDP-glucuronosyltransferases
期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2018, 卷号: 284, 页码: 48-55
作者:
Lv, Xia
;
Zhang, Jian-Bin
;
Wang, Xin-Xin
;
Hu, Wen-Zhong
;
Shi, Yu-Sheng
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/06/20
Amentoflavone
Udp-glucuronosyltransferases
Broad-spectrum Inhibitor
Herb-drug Interactions (Hdis)
Disposition of Mianserin and Cyclizine in UGT2B10-Overexpressing Human Embryonic Kidney 293 Cells: Identification of UGT2B10 as a Novel N-Glucosidation Enzyme and Breast Cancer Resistance Protein as an N-Glucoside Transporter
期刊论文
Drug Metabolism and Disposition, 2018
作者:
Danyi Lu
;
Dong Dong
;
Qian Xie
;
Zhijie Li
;
Baojian Wu
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/31
In Vitro Evaluation of the Effect of 7-Methyl Substitution on Glucuronidation of Daphnetin: Metabolic Stability, Isoform Selectivity, and Bioactivity Analysis
期刊论文
journal of pharmaceutical sciences, 2015, 卷号: 104, 期号: 10, 页码: 3557-3564
作者:
Liang, Si-Cheng
;
Ge, Guang-Bo
;
Xia, Yang-Liu
;
Zhang, Jiang-Wei
;
Qi, Xiao-Yi
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2015/11/17
daphnetin
glucuronidation
methyl substitution
structural modification
metabolic stability
phase II enzymes
glucuronosyltransferases
human liver microsomes
enzyme kinetics
metabolic clearance
Structural Modifications at the C-4 Position Strongly Affect the Glucuronidation of 6,7-Dihydroxycoumarins
期刊论文
drug metabolism and disposition, 2015, 卷号: 43, 期号: 4, 页码: 553-560
作者:
Xia, Yang-Liu
;
Ge, Guang-Bo
;
Wang, Ping
;
Liang, Si-Cheng
;
He, Yu-Qi
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2015/11/17
Selectivity for inhibition of nilotinib on the catalytic activity of human UDP-glucuronosyltransferases
期刊论文
xenobiotica, 2014, 卷号: 44, 期号: 4, 页码: 320-325
作者:
Ai, Limei
;
Zhu, Liangliang
;
Yang, Lu
;
Ge, Guangbo
;
Cao, Yunfeng
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2015/11/13
Niloinib
the selective inhibitor
UDP-glucuronosyltransferase 1A1
Metabolism and Pharmacokinetics of Novel Selective Vascular Endothelial Growth Factor Receptor-2 Inhibitor Apatinib in Humans
期刊论文
DRUG METABOLISM AND DISPOSITION, 2013, 卷号: 41, 期号: 6, 页码: 1195-1210
作者:
Ding, Juefang
;
Chen, Xiaoyan
;
Gao, Zhiwei
;
Dai, Xiaojian
;
Li, Liang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Clinical pharmacokinetics of small molecule tyrosine kinase inhibitors
期刊论文
Acta Pharmaceutica Sinica, 2013, 卷号: 48, 期号: 7, 页码: 1080-1090
作者:
Ding Juefang
;
Zhong Dafang
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
tyrosine kinase inhibitor
pharmacokinetics
drug-drug interaction
Characterization of UDP-Glucuronosyltransferases Involved in Glucuronidation of Diethylstilbestrol in Human Liver and Intestine
期刊论文
chemical research in toxicology, 2012, 卷号: 25, 期号: 12, 页码: 2663-2669
作者:
Zhu, Liangliang
;
Ge, Guangbo
;
Liu, Yong
;
Guo, Zhimou
;
Peng, Chengcheng
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2013/10/11
Potent and selective inhibition of magnolol on catalytic activities of UGT1A7 and 1A9
期刊论文
xenobiotica, 2012, 卷号: 42, 期号: 10, 页码: 1001-1008
作者:
Zhu, Liangliang
;
Ge, Guangbo
;
Liu, Yong
;
He, Guiyuan
;
Liang, Sicheng
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2013/10/11
Magnolol
UDP-glucuronosyltransferases
glucuronidation
UGT inhibitor
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