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Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor Agonists
期刊论文
PHARMACEUTICALS, 2022, 卷号: 15
作者:
Sun, Lei
;
Zheng, Zhi-Ming
;
Shao, Chang-Sheng
;
Zhang, Zhi-Yong
;
Li, Ming-Wei
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/12/22
glucagon-like peptide-1
GLP-1 receptor agonist
functional protein design
molecular dynamics simulation
long-acting antihyperglycemic
DNA methylation and expression profiles of placenta and umbilical cord blood reveal the characteristics of gestational diabetes mellitus patients and offspring
期刊论文
Clinical Epigenetics, 2022, 卷号: 14
作者:
Lu,Sha
;
Wang,Jiahao
;
Kakongoma,Nisile
;
Hua,Wen
;
Xu,Jiahui
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2022/12/22
Gestational diabetes mellitus
Placenta
Umbilical cord blood
Offspring
DNA methylation
Transcriptome
Characterization of microbiome and metabolite analyses in patients with metabolic associated fatty liver disease and type II diabetes mellitus
期刊论文
BMC MICROBIOLOGY, 2022, 卷号: 22
作者:
Yang, Qiuping
;
Zhang, Leisheng
;
Li, Qian
;
Gu, Man
;
Qu, Qiu
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/05/16
Metabolic associated fatty liver disease (MAFLD)
Type II diabetes mellitus (T2DM)
Gut microbiota
Metabolome
Clinical diagnosis
Advanced glycation end products via skin autofluorescence as potential marker of carotid atherosclerosis in patients with type 2 diabetes
期刊论文
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, 2021, 卷号: 31
作者:
Ying, Lingwen
;
Shen, Yun
;
Zhang, Yang
;
Wang, Yikun
;
Liu, Yong
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/01/10
Advanced glycation end products
Carotid atherosclerosis
Cardiovascular events
Non-invasive
Type 2 diabetes
Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site
期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 11, 页码: 2444-2452
作者:
Wang, Jiang
;
Yang, Dehua
;
Cheng, Xi
;
Yang, Linlin
;
Wang, Zhaohui
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  |  
浏览/下载:27/0
  |  
提交时间:2022/01/04
Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11
作者:
Cong, Zhaotong
;
Chen, Li-Nan
;
Ma, Honglei
;
Zhou, Qingtong
;
Zou, Xinyu
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2021/08/17
The effect of ambient ozone on glucose-homoeostasis: A prospective study of non-diabetic older adults in Beijing
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2021, 卷号: 761, 页码: 13
作者:
Li, Ang
;
Mei, Yayuan
;
Zhao, Meiduo
;
Xu, Jing
;
Seery, Samuel
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/03/15
Glucose homeostasis
Glucose metabolism disorder
Longitudinal study
O3
Bio-inspired amyloid polypeptides: From self-assembly to nanostructure design and biotechnological applications
期刊论文
APPLIED MATERIALS TODAY, 2021, 卷号: 22, 页码: 23
作者:
Lai, Yi
;
Li, Fenglin
;
Zou, Zhifeng
;
Saeed, Madiha
;
Xu, Zhiai
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
Amyloid polypeptide
Bio-inspired
Nanomedicine
Self-assembly
All-atom structure ensembles of islet amyloid polypeptides determined by enhanced sampling and experiment data restraints
期刊论文
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2019, 卷号: 87, 期号: 7, 页码: 541-550
作者:
Su, Xinyue
;
Wang, Ke
;
Liu, Na
;
Chen, Jiawen
;
Li, Yong
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2019/10/14
aggregation
chemical shift restraint
islet amylod polypeptide
metadynamics
Synthesis and PTP1B Inhibitory Activity of Novel Chalcone Derivatives Bearing 1H-Benzo[d]imidazol or 1H-Benzo[d][1,2,3]triazol Moieties
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2019, 卷号: 39, 期号: 4, 页码: 1029-1036
作者:
Fu Yang
;
Sheng Li
;
Gao Lixin
;
Li Jia
;
Sun Liangpeng
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/07/01
PTP1B inhibitor
1H-benzo[d]imidazol
1H-benzo[d][1,2,3]triazol
chalcone
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