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生态环境研究中心 [12]
水生生物研究所 [8]
厦门大学 [5]
兰州大学 [4]
武汉大学 [3]
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期刊论文 [40]
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学位论文 [2]
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Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways
期刊论文
ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2021, 卷号: 9, 期号: 11, 页码: 4130-4138
作者:
Wang, Xiaoqing
;
Li, Fei
;
Chen, Jingwen
;
Ji, Chenglong
;
Wu, Huifeng
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/22
Adverse outcome pathway (AOP)
Comparative toxicogenomics database (CTD)
Triphenyl phosphate (TPP)
Molecular dynamics (MD)
Transcriptome analyses
TDCPP mimics thyroid hormones associated with the activation of integrin alpha(v)beta(3) and ERK1/2
期刊论文
CHEMOSPHERE, 2020, 卷号: 256, 页码: 1-9
作者:
Li, Jian
;
Liu, Hedan
;
Li, Na
;
Wang, Jinsheng
;
Song, Liuting
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/09/15
TDCPP
BDCPP
Thyroid disruption
Integrin alpha(v)beta(3)
ERK1/2
德克隆类化合物对甲状腺系统的干扰效应及其分子机制
学位论文
北京: 中国科学院生态环境研究中心, 2020
作者:
朱剑桥
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/07/07
德克隆类化合物、甲状腺激素受体、竞争结合、t-screen、报告基因
Dechloranes, Thyroid Hormone Receptor, Ligand Binding Assay, T-screen Assay, Reporter Gene Assay
Competitive binding assays for measuring the binding affinity of thyroid-disrupting chemicals for integrin alpha(v)beta(3)
期刊论文
CHEMOSPHERE, 2020, 卷号: 249, 页码: 1-8
作者:
Li, Jian
;
Liu, Hedan
;
Zuo, Rui
;
Yang, Jie
;
Li, Na
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/09/15
Thyroid-disrupting chemicals
Integrin alpha(v)beta(3)
Competitive binding assay
T4-BSA-F
Tc-99m-3PRGD(2)
Phthalate esters
Evaluation and mechanistic study of chlordecone-induced thyroid disruption: Based on in vivo, in vitro and in silico assays
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2020, 卷号: 716, 页码: 1-10
作者:
Yang, Lihua
;
Zha, Jinmiao
;
Guo, Yongyong
;
Zhou, Bingsheng
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2021/09/15
Chlordecone
Thyroid disruption
Rare minnow
GH3 cells
Estrogen receptor
The molecular mechanism of the antagonistic activity of hydroxylated polybrominated biphenyl (OH-BB80) toward thyroid receptor beta
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2019, 卷号: 697, 页码: -
作者:
Zhang, Xiaofang
;
Cui, Shixuan
;
Pan, Liumeng
;
Dong, Wenhua
;
Ma, Mei
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/09/10
Hydroxylated brominated biphenyls
Endocrine disrupting effect
Molecular interactions
Metabolic activation
A comparison of endocrine disruption potential of nonylphenol ethoxylate, vanillin ethoxylate, 4-n-nonylphenol and vanillin in vitro
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 175, 页码: 208-214
作者:
Ji, Xiaoya
;
Li, Na
;
Yuan, Shengwu
;
Zhou, Xiaohong
;
Ding, Fengmei
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/10/23
Nonylphenol ethoxylate
Vanillin ethoxylate
4-n-nonylphenol
Vanillin
Nuclear receptors
Two-hybrid yeast
Mechanism of the Endocrine-Disruptive Effects of Low-Dose Bisphenol A via Transmembrane Receptor
期刊论文
PROGRESS IN CHEMISTRY, 2019, 卷号: 31, 期号: 1, 页码: 167-179
作者:
Zhu, Benzhan
;
Shen, Chen
;
Sheng, Zhiguo
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/10/21
bisphenol A
low-dose effect
G protein-coupled receptor 30
integrin alpha v beta 3
toxic effect
Thyroid Disruption by Bisphenol S Analogues via Thyroid Hormone Receptor beta: in Vitro, in Vivo, and Molecular Dynamics Simulation Study
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2018, 卷号: 52, 期号: 11, 页码: 6617-6625
作者:
Zhuang, Shulin
;
Liu, Weiping
;
Zhang, Chunlong
;
Wang, Jingpeng
;
Xu, Chao
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/06/24
Tetrabromobisphenol A caused neurodevelopmental toxicity via disrupting thyroid hormones in zebrafish larvae
期刊论文
CHEMOSPHERE, 2018, 卷号: 197, 期号: 1, 页码: 353-361
作者:
Zhu, Biran
;
Zhao, Gang
;
Yang, Lihua
;
Zhou, Bingsheng
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/07/03
Tetrabromobisphenol A (TBBPA)
Zebrafish (Danio rerio)
Thyroid disruption
Neurodevelopmental toxicity
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