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北京大学 [2]
复旦大学上海医学院 [2]
清华大学 [1]
厦门大学 [1]
上海药物研究所 [1]
山东大学 [1]
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期刊论文 [11]
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2015 [1]
2013 [4]
2011 [1]
2010 [1]
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Human Liver Cytochrome P450 Enzymes and Microsomal Thiol Methyltransferase Are Involved in the Stereoselective Formation and Methylation of the Pharmacologically Active Metabolite of Clopidogrel
期刊论文
DRUG METABOLISM AND DISPOSITION, 2015, 卷号: 43, 期号: 10, 页码: 1632-1641
作者:
Liu, Cai
;
Chen, Zhaoqiang
;
Zhong, Kan
;
Li, Liang
;
Zhu, Weiliang
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
In Vitro Biotransformation Studies of 2-Oxo-clopidogrel: Multiple Thiolactone Ring-Opening Pathways Further Attenuate Prodrug Activation
期刊论文
毒物学领域的化学研究, 2013
Zhu, Yaoqiu
;
Zhou, Jiang
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/11/13
CLOPIDOGREL BIOACTIVATION
ACTIVE METABOLITE
IDENTIFICATION
TICLOPIDINE
RESISTANCE
PRASUGREL
THIENOPYRIDINE
DISPOSITION
INVOLVEMENT
GLUTATHIONE
Deuterated Clopidogrel Analogues as a New Generation of Antiplatelet Agents
期刊论文
acs medicinal chemistry letters, 2013
Zhu, Yaoqiu
;
Zhou, Jiang
;
Jiao, Bo
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2015/11/11
Clopidogrel resistance
clinical variability
prodrug attrition
piperidine deuteration
targeted metabolic shift
bioactivation potentiation
ADENOSINE DIPHOSPHATE
ACTIVE METABOLITE
BIOACTIVATION
RESISTANCE
IDENTIFICATION
AGGREGATION
INVOLVEMENT
TICLOPIDINE
PREVENTION
MECHANISM
Detection and characterization of ticlopidine conjugates in rat bile using high-resolution mass spectrometry: Applications of various data acquisition and processing tools
期刊论文
Journal of mass spectrometry: JMS, 2013, 卷号: 48, 期号: 3, 页码: 413-422
作者:
Du, F.
;
Ruan, Q.
;
Zhu, M.
;
Xing, J.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/23
conjugates
high-resolution mass spectrometry
isotope pattern filter
mass defect filter
ticlopidine
Comparison of cilostazol versus ticlopidine following coronary stenting in patients with coronary heart disease: A meta-analysis of randomized controlled trials
期刊论文
2013, 卷号: 6, 期号: 3, 页码: 819-825
作者:
Hu, Feng-Huan
;
Yi, Xin
;
Yang, Yue-Jing
;
Qiao, Shu-Bin
;
Wu, Yong-Jian
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/13
coronary heart disease
coronary stenting
cilostazol
ticlopidine
meta-analysis
Metabolism of dl-Praeruptorin A in Rat Liver Microsomes using HPLC-Electrospray Ionization Tandem Mass Spectrometry
期刊论文
http://dx.doi.org/10.1007/s12272-011-0811-y, 2011
Ruan, Hang
;
Zhang, Zhen
;
Liang, Xin-fang
;
Fu, Yan
;
Su, Mei-qin
;
Liu, Qi-lin
;
Wang, Xiu-min
;
Zhu, Xuan
;
王秀敏
;
朱铉
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  |  
浏览/下载:5/0
  |  
提交时间:2015/07/22
LIQUID-CHROMATOGRAPHY
PEUCEDANUM-PRAERUPTORUM
INHIBITION
COUMARIN
DRUG
CYTOCHROME-P-450
PHARMACOKINETICS
EXPRESSION
OXIDATION
INDUCERS
合并糖尿病的老年女性急性心肌梗死患者发病早期治疗现状分析
期刊论文
2010, 2010
张迅英
;
张琴
;
曾勇
;
孟海燕
;
曹万才
;
黄超联
;
ZHANG Xun-ying
;
ZHANG Qin
;
ZENG Yong
收藏
  |  
浏览/下载:3/0
Molecular modeling of purinergic receptor P2Y12 and interaction with its antagonists
期刊论文
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2007, 卷号: 26, 期号: 1, 页码: 20-31
作者:
Zhan, C
;
Yang, J
;
Dong, XC
;
Wang, YL
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2015/07/22
P2Y12
ADP receptor
antagonists
ATP
platelets aggregation
RACTS: A prospective randomized antiplatelet trial of cilostazol versus ticlopidine in patients undergoing coronary stenting long-term clinical and angiographic outcome - Long-term clinical and angiographic outcome
期刊论文
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2005, 卷号: 46, 期号: 2
作者:
Ge, JB
;
Han, YL
;
Jiang, H
;
Sun, BG
;
Chen, JY
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/27
cilostazol
platelet aggregation inhibitors
restenosis
side effect
ticlopidine
Comparison of beraprost and ticlopicline in Chinese patients with chronic peripheral arterial occlusion: A multicenter, single-blind, randomized, controlled study
期刊论文
CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, 2003, 卷号: 64, 期号: 7
作者:
Guan, H
;
Wang, YQ
;
Zhang, BG
;
Ye, W
;
Fu, WG
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/27
beraprost
ticlopidine
prostaglandin I-2 analogue
peripheral arterial occlusion
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