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Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:
Meng, Xiang-Dong
;
Gao, Li-Xin
;
Wang, Zhi-Jia
;
Feng, Bo
;
Zhang, Chun
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/12/01
2,5-diphenyl-1,3,4-oxadiazole derivatives
SHP2
Inhibitors
Structure-activity relationships (SAR)
Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030
作者:
Liu, Xiao
;
Jiang, Shuang
;
Kong, Linghui
;
Ye, Rongrong
;
Xiao, Li
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  |  
浏览/下载:113/0
  |  
提交时间:2021/05/24
Morphinans
arylacetamidyl substituent
kappa opioid receptor modulators
structure-activity relationships
Synthesis and Structure-Activity Relationships of Ring-Opened Bengamide Analogues against Methicillin-Resistant Staphylococcus aureus(dagger)
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2021, 卷号: 39, 期号: 3, 页码: 671-676
作者:
Yu, Chen-Xi
;
Wei, Bing-Yan
;
Kong, Xue-Qing
;
Yang, Cai-Guang
;
Nan, Fa-Jun
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  |  
浏览/下载:41/0
  |  
提交时间:2021/05/24
Bengamides
Staphylococcus aureus
Antibiotics
Structure‐
activity relationships
Pharmacokinetic
Vacancies on 2D transition metal dichalcogenides elicit ferroptotic cell death
期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 1-9
作者:
Xu, Shujuan
;
Zheng, Huizhen
;
Ma, Ronglin
;
Wu, Di
;
Pan, Yanxia
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  |  
浏览/下载:28/0
  |  
提交时间:2021/09/14
Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 11, 页码: 5
作者:
Satheeshkumar, Rajendran
;
Zhu, Rui
;
Feng, Bo
;
Huang, Chao
;
Gao, Ya
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  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Heterocyclic bis-aryl amides
PTP1B
SHP2
Inhibitors
Structure-activity relationships (SAR)
Synthesis of triazolotriazine derivatives as c-Met inhibitors
期刊论文
MOLECULAR DIVERSITY, 2020, 页码: 8
作者:
Guo, Yuting
;
Peng, Xia
;
Ji, Yinchun
;
Zhang, Yitong
;
Ding, Jian
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  |  
浏览/下载:37/0
  |  
提交时间:2020/12/24
Receptor tyrosine kinase
c-Met
Triazolotriazine
SAR
Cellular potency
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists
期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:
Chen, Duo-zhi
;
Yang, Bi-juan
;
He, Xiao-li
;
Fan, Shi-rui
;
Cai, Jie-yun
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  |  
浏览/下载:113/0
  |  
提交时间:2019/03/18
Wnt/beta-catenin signalling pathway agonist
Phenanthridine derivatives
Structural optimization
Structure-activity relationships (SARs)
Prediction of the binding affinity of aptamers against the influenza virus.
期刊论文
SAR & QSAR in Environmental Research, 2019, 卷号: Vol.30 No.1, 页码: 51-62
作者:
Yu, X
;
Wang, Y
;
Yang, H
;
Huang, X
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/13
APTAMERS
*INFLUENZA viruses
*STRUCTURE-activity relationships (Biochemistry)
*AMINO acid sequence
*PREDICTION models
Design, Synthesis and Fungicidal Activity against Rhizoctonia solani of New Phenylpyrazoloxyl Propionic Acid Derivatives
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2019, 卷号: 39, 期号: 2, 页码: 397-405
作者:
Yu Fuqiang
;
Guan Aiying
;
Sun Xufeng
;
Li Huichao
;
Li Xiaowu
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/02/02
phenylpyrazoloxyl propionic acid derivatives
intermediate derivatization method
fungicidal activity
Rhizoctonia solani
structure-activity relationship
Design, Synthesis and Fungicidal Activity against Rhizoctonia solani of New Phenylpyrazoloxyl Propionic Acid Derivatives
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2019, 卷号: 39, 期号: 2, 页码: 397-405
作者:
Yu Fuqiang
;
Guan Aiying
;
Sun Xufeng
;
Li Huichao
;
Li Xiaowu
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2021/02/02
phenylpyrazoloxyl propionic acid derivatives
intermediate derivatization method
fungicidal activity
Rhizoctonia solani
structure-activity relationship
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