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基于八臂PEG聚集和阿拉伯半乳聚糖-PEG修饰的长效葡激酶及其药学性质研究 学位论文
: 中国科学院大学, 2019
作者:  祁芳冰
收藏  |  浏览/下载:4/0  |  提交时间:2020/06/17
Conjugation of staphylokinase with the arabinogalactan-PEG conjugate: Study on the immunogenicity, in vitro bioactivity and pharmacokinetics 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 卷号: 131, 页码: 896-904
作者:  Qi, Fangbing;  Qi, Jinming;  Hu, Chunyang;  Shen, Lijuan;  Yu, Weili
收藏  |  浏览/下载:68/0  |  提交时间:2019/06/14
Conjugation with Eight-Arm PEG Markedly Improves the In Vitro Activity and Prolongs the Blood Circulation of Staphylokinase 期刊论文
BIOCONJUGATE CHEMISTRY, 2018, 卷号: 29, 期号: 2, 页码: 451-458
作者:  Qi, Fangbing;  Hu, Chunyang;  Yu, Weili;  Hu, Tao
收藏  |  浏览/下载:30/0  |  提交时间:2018/06/11
PEGylation with the thiosuccinimido butylamine linker significantly increases the stability of haloalkane dehalogenase DhaA 期刊论文
JOURNAL OF BIOTECHNOLOGY, 2017, 卷号: 254, 页码: 25-33
作者:  Zhao, Yuan-Zhong;  Yu, Wei-Li;  Zheng, He;  Guo, Xuan;  Guo, Nan
收藏  |  浏览/下载:25/0  |  提交时间:2017/09/06
葡激酶的聚乙二醇定点修饰产物制备及药学性质研究 学位论文
博士, 北京: 中国科学院研究生院, 2015
作者:  薛晓莹
收藏  |  浏览/下载:17/0  |  提交时间:2016/03/24
N-Terminal Modification with Pseudo-Bifunctional PEG-Hexadecane Markedly Improves the Pharmacological Profile of Human Growth Hormone 期刊论文
MOLECULAR PHARMACEUTICS, 2015, 卷号: 12, 期号: 5, 页码: 1402-1411
作者:  Wu, Ling;  Ji, Shaoyang;  Hu, Tao
收藏  |  浏览/下载:21/0  |  提交时间:2015/07/05
Phenyl Amide Linker Improves the Pharmacokinetics and Pharmacodynamics of N-Terminally Mono-PEGylated Human Growth Hormone 期刊论文
MOLECULAR PHARMACEUTICS, 2014, 卷号: 11, 期号: 9, 页码: 3080-3089
作者:  Wu, Ling;  Ji, Shaoyang;  Shen, Lijuan;  Hu, Tao
收藏  |  浏览/下载:21/0  |  提交时间:2014/09/30
PEGylated recombinant human interferon-omega as a long-acting antiviral agent: Structure, antiviral activity and pharmacokinetics 期刊论文
ANTIVIRAL RESEARCH, 2014, 卷号: 108, 期号: AUG, 页码: 142-147
作者:  Yu, Weili;  Yu, Changming;  Wu, Ling;  Fang, Ting;  Qiu, Rui
收藏  |  浏览/下载:15/0  |  提交时间:2014/09/30
Heat treatment increases the bioactivity of C-terminally PEGylated staphylokinase 期刊论文
PROCESS BIOCHEMISTRY, 2014, 卷号: 49, 期号: 7, 页码: 1092-1096
作者:  Xue, Xiaoying;  Ji, Shaoyang;  Mu, Qimeng;  Hu, Tao
收藏  |  浏览/下载:18/0  |  提交时间:2014/08/28
PEG as a spacer arm markedly increases the immunogenicity of meningococcal group Y polysaccharide conjugate vaccine 期刊论文
JOURNAL OF CONTROLLED RELEASE, 2013, 卷号: 172, 期号: 1, 页码: 382-389
作者:  Huang, Qingrui;  Li, Dongxia;  Kang, Aijun;  An, Wenqi;  Fan, Bei
收藏  |  浏览/下载:31/0  |  提交时间:2015/05/05


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