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中国医学科学院 北京... [9]
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期刊论文 [27]
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Regulation of hypoxia-inducible factor functions in the nucleus by sphingosine-1-phosphate
期刊论文
FASEB JOURNAL, 2020, 页码: 18
作者:
Hait, Nitai C.
;
Maiti, Aparna
;
Xu, Pan
;
Qi, Qianya
;
Kawaguchi, Tsutomu
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/07/01
hypoxia-inducible factors
sphingosine-1-phosphate
sphingosine kinase 2
triple-negative breast cancer
Identification and Structure-Activity Relationship (SAR) of potent and selective oxadiazole-based agonists of sphingosine-1-phosphate receptor (S1P(1))
期刊论文
2019, 卷号: 82, 页码: 41-57
作者:
Liu, Tianqi
;
Jin, Jing
;
Chen, Yonghui
;
Xi, Qiumu
;
Hu, Jinping
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/01/03
S1P(1) agonist
Oxadiazole
SAR
Lymphocyte
Cascade modification
A Computational Approach to the Study of the Binding Mode of S1P(1)R Agonists Based on the Active-Like Receptor Model
期刊论文
2019, 卷号: 59, 期号: 4, 页码: 1624-1633
作者:
Chen, Yonghui
;
Liu, Tianqi
;
Xi, Qiumu
;
Jia, Wenqiang
;
Yin, Dali
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
SPHK1 promotes metastasis of thyroid carcinoma through activation of the S1P/S1PR3/Notch signaling pathway
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2018, 卷号: 15, 期号: 6
作者:
Zhao, Zhijing
;
Ma, Junfeng
;
Hu, Baoquan
;
Zhang, Yi
;
Wang, Shushu
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/04
thyroid carcinoma
sphingosine kinase 1
sphingosine-1-phosphate
sphingosine-1-phosphate receptor 3
metastasis
Sphingosine 1-Phosphate /S1P Receptor Axis Promotes Inflammatory M1 Polarization of Bone Marrow-Derived Monocyte/Macrophage via G/PI3K/JNK Pathway
期刊论文
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018, 卷号: Vol.49 No.5, 页码: 1677-1693
作者:
Yang, Jingjing
;
Yang, Le
;
Tian, Lei
;
Ji, Xiaofang
;
Yang, Lin
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/26
Sphingosine
1-phosphate
Sphingosine
1-phosphate
receptor
Inflammation
Bone
marrow-derived
monocyte/macrophage
Macrophage
polarization
Signaling
transduction
CYP2J2 is the major enzyme in human liver microsomes responsible for hydroxylation of SYL-927, a novel and selective sphingosine 1-phosphate receptor 1 (S1P(1)) agonist
期刊论文
2018, 卷号: 39, 期号: 9, 页码: 431-436
作者:
Yang, Shu
;
Hu, Jinping
;
Li, Yan
;
Zhao, Zhigang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
CYP2J2
human liver microsomes
S1P(1) agonist
omega-1 hydroxylation
Validating a Selective S1P(1) Receptor Modulator Sy1930 for Psoriasis Treatment
期刊论文
2018, 卷号: 41, 期号: 4, 页码: 592-596
作者:
Ji, Ming
;
Xue, Nina
;
Lai, Fangfang
;
Zhang, Xiaoying
;
Zhang, Sen
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/01/03
psoriasis
sphingolipid sphingosine-1-phosphate (S1P)
S1P(1 ) modulator
Sy1930
animal model
Targeting sphingosine-1-phosphate signaling for cancer therapy
期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2017, 卷号: 60, 期号: 6, 页码: 585-600
作者:
Xie, Zuoquan
;
Liu, Hong
;
Geng, Meiyu
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/01/08
sphingosine-1-phosphate
sphingosine
ceramide
cancer
inflammation
immunity
The sphingosine-1-phosphate analogue, FTY-720, promotes the proliferation of embryonic neural stem cells, enhances hippocampal neurogenesis and learning and memory abilities in adult mice
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2016, 卷号: 173, 期号: 18, 页码: 2793-2807
作者:
Sun, Yili
;
Hong, Feng
;
Zhang, Lei
;
Feng, Linyin
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Pharmacokinetics of H002, a novel S1PR(1) modulator, and its metabolites in rat blood using liquid chromatography-tandem mass spectrometry
期刊论文
2016, 卷号: 6, 期号: 6, 页码: 576-583
作者:
Mi, Jiaqi
;
Zhao, Manman
;
Yang, Shu
;
Yang, Shuang
;
Jin, Jing
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/04
S1P receptor
S1PR(1) modulator-1-phosphate
SIP analogue
Metabolite
LC-MS/MS
Phamiacokinetics
Periphery blood lymphocyte
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