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The cross-talk between methylation and phosphorylation in lymphoid-specific helicase drives cancer stem-like properties 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5, 期号: 1, 页码: 14
作者:  Liu, Na;  Yang, Rui;  Shi, Ying;  Chen, Ling;  Liu, Yating
收藏  |  浏览/下载:35/0  |  提交时间:2020/12/21
Discovery of 2-substituted-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide as potent and selective protein arginine methyltransferases 5 inhibitors: Design, synthesis and biological evaluation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 164, 页码: 317-333
作者:  Shao, Jingwei;  Zhu, Kongkai;  Du, Daohai;  Zhang, Yuanyuan;  Tao, Hongrui
收藏  |  浏览/下载:35/0  |  提交时间:2020/07/01
A patent review of arginine methyltransferase inhibitors (2010-2018) 期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2019, 卷号: 29, 期号: 2, 页码: 97-114
作者:  Li, Xiao;  Wang, Chen;  Jiang, Hao;  Luo, Cheng
收藏  |  浏览/下载:8/0  |  提交时间:2020/07/01
Reduced asymmetric dimethylarginine accumulation through inhibition of the type I protein arginine methyltransferases promotes renal fibrosis in obstructed kidneys 期刊论文
FASEB JOURNAL, 2019, 卷号: 33, 期号: 6
作者:  Wu, Ming;  Lin, Pinglan;  Li, Lin;  Chen, Dongping;  Yang, Xuejun
收藏  |  浏览/下载:22/0  |  提交时间:2019/12/05
PRMT1  ADMA  NO  CKD  
Identification of Selective, Cell Active Inhibitors of Protein Arginine Methyltransferase 5 through Structure-Based Virtual Screening and Biological Assays 期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2018, 卷号: 58, 期号: 5, 页码: 1066-1073
作者:  Ye, Fei;  Zhang, Weiyao;  Ye, Xiaoqing;  Jin, Jia;  Lv, Zhengbing
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08
Detection of PRMT1 inhibitors with stopped flow fluorescence 期刊论文
Signal transduction and targeted therapy, 2018, 卷号: 3, 页码: 6
作者:  Qian, Kun;  Hu, Hao;  Xu, Hui;  Zheng, Y George
收藏  |  浏览/下载:59/0  |  提交时间:2019/01/08
Discovery of alkyl bis(oxy)dibenzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2017, 卷号: 90, 期号: 6, 页码: 1260-1270
作者:  Zhang, Wei-yao;  Lu, Wen-chao;  Jiang, Hao;  Lv, Zheng-bing;  Xie, Yi-qian
收藏  |  浏览/下载:32/0  |  提交时间:2019/01/08
Development of Potent Type I Protein Arginine Methyltransferase (PRMT) Inhibitors of Leukemia Cell Proliferation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 21, 页码: 8888-8905
作者:  Wang, Chen;  Jiang, Hao;  Jin, Jia;  Xie, Yiqian;  Chen, Zhifeng
收藏  |  浏览/下载:114/0  |  提交时间:2019/01/08
Potent, Selective, and Cell Active Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor Developed by Structure-Based Virtual Screening and Hit Optimization 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 14, 页码: 6289-6304
作者:  Mao, Ruifeng;  Shao, Jingwei;  Zhu, Kongkai;  Zhang, Yuanyuan;  Ding, Hong
收藏  |  浏览/下载:91/0  |  提交时间:2019/01/08
Transient Kinetics Define a Complete Kinetic Model for Protein Arginine Methyltransferase 1 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 291, 期号: 52, 页码: 26722-26738
作者:  Hu, Hao;  Luo, Cheng;  Zheng, Y. George
收藏  |  浏览/下载:11/0  |  提交时间:2019/01/08


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