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上海药物研究所 [4]
昆明动物研究所 [2]
兰州大学 [1]
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期刊论文 [13]
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2021 [1]
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TANK-binding kinase 1 (TBK1): An emerging therapeutic target for drug discovery
期刊论文
DRUG DISCOVERY TODAY, 2021, 卷号: 26, 期号: 10, 页码: 2445-2455
作者:
Xiang, Shuang
;
Song, Shukai
;
Tang, Haotian
;
Smaill, Jeff B.
;
Wang, Aiqun
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/12/01
Antibiotic resistance
Computational biology
Databases
In silico tools
Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 44, 页码: 27381-27387
作者:
Li, Zhe
;
Li, Xin
;
Huang, Yi-You
;
Wu, Yaoxing
;
Liu, Runduo
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2020/12/24
virtual screening
SARS-CoV-2
drug repurposing
free energy perturbation
main protease
Structure of M-pro from SARS-CoV-2 and discovery of its inhibitors
期刊论文
NATURE, 2020, 页码: 24
作者:
Jin, Zhenming
;
Du, Xiaoyu
;
Xu, Yechun
;
Deng, Yongqiang
;
Liu, Meiqin
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
Protein Kinase Inhibitors as Potential Antimicrobial Drugs Against Tuberculosis, Malaria and HIV
期刊论文
CURRENT PHARMACEUTICAL DESIGN, 2017, 卷号: 23, 期号: 29, 页码: 4369-4389
作者:
Cheng, Yong
;
Schorey, Jeffrey S.
;
Zhang, Cheng-Cai
;
Tan, Xuejuan
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/07/03
Protein kinase inhibitors
antimicrobial drugs
infectious diseases
tuberculosis
malaria
AIDS
Synthesis and Anti-HIV-1 Activity Evaluation for Novel 3a,6a-Dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives
期刊论文
MOLECULES, 2016, 卷号: 21, 期号: 9
作者:
Liu, Guan-Nan
;
Luo, Rong-Hua
;
Zhou, Yu
;
Zhang, Xing-Jie
;
Li, Jian
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
anti-HIV-1
integrase
synthesis
SAR
AIDS
Generation and characterization of novel DNA aptamers against coat protein of grouper nervous necrosis virus (GNNV) with antiviral activities and delivery potential in grouper cells
期刊论文
ANTIVIRAL RESEARCH, 2016, 卷号: 129, 页码: 104-114
作者:
Zhou, Lingli
;
Li, Pengfei
;
Yang, Min
;
Yu, Yepin
;
Huang, Youhua
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2016/12/23
Aptamer
SELEX
Grouper nervous necrosis virus
Coat protein
Antiviral activity
Synthesis and Anti-HIV-1 Activity Evaluation for Novel 3a,6a-Dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives
期刊论文
Molecules, 2016, 卷号: 21, 期号: 9, 页码: e1198
作者:
Liu GN
;
Luo RH
;
Yang LM
;
Zheng YT[*]
;
Liu H[*]
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2016/09/18
AIDS
SAR
anti-HIV-1
integrase
synthesis
Antiviral effects of two Ganoderma lucidum triterpenoids against enterovirus 71 infection
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2014, 卷号: 449, 期号: 3, 页码: 307-312
作者:
Zhang, Wenjing
;
Tao, Junyan
;
Yang, Xiaoping
;
Yang, Zhuliang
;
Zhang, Li
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2014/07/28
Enterovirus 71 (EV71)
Virus infection
Hand-foot-mouth disease (HFMD)
Ganoderma lucidum triterpenoids (GLTs)
Antiviral activity
Potential therapeutic antiviral agents
Inhibition of hepatitis C virus infection by NS5A-specific aptamer
期刊论文
ANTIVIRAL RESEARCH, 2014, 卷号: 106, 页码: 116-124
作者:
Yu, Xiaoyan
;
Gao, Yimin
;
Xue, Binbin
;
Wang, Xiaohong
;
Yang, Darong
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/04/09
Hcv
Ns5a
Aptamer
Antivirals
Replication
Mutation
Humanized PA14 (a monoclonal CCR5 antibody) for treatment of people with HIV infection
期刊论文
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2014, 期号: 7, 页码: -
作者:
Li, L
;
Tian, JH
;
Yang, KH
;
Zhang, P
;
Jia, WQ
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2015/12/22
HIV-1 [genetics]
Anti-HIV Agents [therapeutic use]
Antibodies, Monoclonal [therapeutic use]
Antibodies, Monoclonal, Humanized
HIV Antibodies [therapeutic use]
HIV Infections [drug therapy]
RNA, Viral [blood]
Randomized Controlled Trials as Topic
Receptors, CCR5 [antagonists & inhibitors]
Adult
Humans
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