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大连理工大学 [4]
上海药物研究所 [3]
中国医学科学院 北京... [3]
青岛生物能源与过程研... [2]
上海中医药大学 [2]
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期刊论文 [20]
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Galangin (GG) combined with cisplatin (DDP) to suppress human lung cancer by inhibition of STAT3-regulated NF-κB and Bcl-2/Bax signaling pathways
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 97, 页码: 213-224
作者:
Yu, Shuo
;
Gong, Lian-sheng*
;
Li, Nian-feng
;
Pan, Yi-feng
;
Zhang, Lun
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/03
MTT
3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide
GG
Galangin
DDP
cisplatin
STAT3
signal transducers and activation of transcription
LC
Lung cancer
MDR
multidrug resistance
NSCL
Cnon-small cell lung cancer
Bcl-2
B-cell leukemia/lymphoma 2
Bax
bcl-2-like protein
TRAIL
TNF-related apoptosis-inducing ligand
NF-κB
nuclear factor kappa-light-chain-enhancer of activated B cells
IκBα
inhibitor of NF-κBα
Cyto-c
cytochrome c
Lung cancer
Galangin
Cisplatin
p-STAT3/p65
Bcl-2
Inhibition of Mcl-1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells
期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2017, 卷号: 2
作者:
Luedtke, Daniel A.
;
Niu, Xiaojia
;
Pan, Yihang
;
Zhao, Jianyun
;
Liu, Shuang
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
MCL-1 Up-Regulation through MAPK Activation Confers Acquired Resistance to BCL-2 Inhibitor ABT-199 in Pre-Clinical AML Models
期刊论文
2017, 卷号: 17, 期号: 10, 页码: S2-S2
作者:
Zhang, Qi
;
Han, Lina
;
Pan, Rongqing
;
Shi, Ce
;
Jeremy, Ryan
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  |  
浏览/下载:4/0
  |  
提交时间:2020/01/04
Upregulation of MAPK/MCL-1 Maintaining Mitochondrial Oxidative Phosphorylation Confers Acquired Resistance to BCL-2 Inhibitor Venetoclax in AML
期刊论文
2016, 卷号: 128, 期号: 22
作者:
Zhang, Qi
;
Han, Lina
;
Shi, Ce
;
Pan, Rongqing
;
Ma, Man Chun John
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/04
Upregulation of MAPK/MCL-1 Maintaining Mitochondrial Oxidative Phosphorylation Confers Acquired Resistance to BCL-2 Inhibitor Venetoclax in AML
会议论文
BLOOD, 2016-12-02
作者:
Zhang, Qi
;
Han, Lina
;
Shi, Ce
;
Pan, Rongqing
;
Ma, Man Chun John
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/04
AT-101 inhibits hedgehog pathway activity and cancer growth
期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2015, 卷号: 76, 期号: 3, 页码: 461-469
作者:
Wang, Juan
;
Peng, Yuanqiu
;
Liu, Yuan
;
Yang, Jun
;
Huang, Ming
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  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Hedgehog
AT-101
Gossypol
Medulloblastoma
Smoothened
A novel dithiocarbamate derivative induces cell apoptosis through p53-dependent intrinsic pathway and suppresses the expression of the E6 oncogene of human papillomavirus 18 in HeLa cells
期刊论文
APOPTOSIS, 2015, 卷号: 20, 期号: 6, 页码: 787-795
作者:
Li, YH (Li, Yanhong)
;
Qi, HX (Qi, Hongxue)
;
Li, XB (Li, Xiaobo)
;
Hou, XL (Hou, Xueling)
;
Lu, XY (Lu, Xueying)
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  |  
浏览/下载:26/0
  |  
提交时间:2015/07/11
Dithiocarbamate derivative
Apoptosis
Caspase
P53-Dependent intrinsic pathway
HPV18 E6
Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction
期刊论文
CELL RESEARCH, 2015, 卷号: 25, 期号: 8, 页码: 946-962
作者:
Jia, XE
;
Ma, K
;
Xu, T
;
Gao, L
;
Wu, S
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2015/12/30
UNFOLDED PROTEIN RESPONSE
DIAMOND-BLACKFAN ANEMIA
BCL-X-L
STEM-CELLS
EMBRYONIC-DEVELOPMENT
ZEBRAFISH DEVELOPMENT
MONITORING AUTOPHAGY
RIBOSOME BIOGENESIS
ERYTHROID-CELLS
QUALITY CONTROL
3-Thiomorpholin-8-oxo-8H-acenaphtho [1,2-b] pyrrole-9-carbonitrile (S1) derivatives as pan-Bcl-2-inhibitors of Bcl-2, Bcl-x(L) and Mcl-1
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 1, 页码: 11-20
作者:
Song, Ting
;
Li, Xiangqian
;
Chang, Xilong
;
Liang, Xiaomeng
;
Zhao, Yan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2015/11/02
Pan-Bcl-2 inhibitor
Bcl-2
Mcl-1
p4 Pocket
Apoptosis
3-Thiomorpholin-8-oxo-8H-acenaphtho [1,2-b] pyrrole-9-carbonitrile (S1) derivatives as pan-Bcl-2-inhibitors of Bcl-2, Bcl-xL and Mcl-1. [Research Support, Non-U.S. Gov't]
期刊论文
Bioorg Med Chem, 2013, 卷号: 21, 期号: 1, 页码: 11-20
Song, T.
;
Li, X.
;
Chang, X.
;
Liang, X.
;
Zhao, Y.
;
Wu, G.
;
. . . Zhang, Z.
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2014/03/14
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