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上海药物研究所 [24]
复旦大学上海医学院 [16]
昆明植物研究所 [13]
昆明动物研究所 [10]
厦门大学 [9]
北京大学 [9]
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期刊论文 [125]
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浏览/检索结果:
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Gigantol ameliorates CCl4-induced liver injury via preventing activation of JNK/cPLA2/12-LOX inflammatory pathway
期刊论文
SCIENTIFIC REPORTS, 2020, 卷号: 10, 期号: 1, 页码: 13
作者:
Xue, Yaru
;
Deng, Qiangqiang
;
Zhang, Qingli
;
Ma, Zhenghua
;
Chen, Binfan
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
Potent and rapid reversal of the von Willebrand factor inhibitor aptamer BT200
期刊论文
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2020, 页码: 10
作者:
Zhu, Shuhao
;
Gilbert, James C.
;
Liang, Zicai
;
Kang, Daiwu
;
Li, Ming
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/12/24
glycoprotein Ib
platelet
reversal agent
thrombosis
von Willebrand factor
Lipoprotein-associated phospholipase A2: The story continues
期刊论文
MEDICINAL RESEARCH REVIEWS, 2020, 卷号: 40, 期号: 1, 页码: 79-134
作者:
Huang, Fubao
;
Wang, Kai
;
Shen, Jianhua
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
fragment-based lead discovery
inflammation
inhibitors
lipoprotein-associated phospholipase A2
vascular diseases
Biflavones from Ginkgo biloba as inhibitors of human thrombin
期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 92, 页码: 10
作者:
Chen, Tian-Ran
;
Wei, Ling-Hua
;
Guan, Xiao-Qing
;
Huang, Chao
;
Liu, Zhe-Yi
收藏
  |  
浏览/下载:145/0
  |  
提交时间:2019/12/02
Ginkgo biloba
Thrombin
Proteolytic activity
Biflavones
Inhibitory effects
Precise Structure and Anticoagulant Activity of Fucosylated Glycosaminoglycan from Apostichopus japonicus: Analysis of Its Depolymerized Fragments
期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 4, 页码: 13
作者:
Guan, Ruowei
;
Peng, Yuan
;
Zhou, Lutan
;
Zheng, Wenqi
;
Liu, Xixi
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2019/06/24
Apostichopus japonicus
fucosylated glycosaminoglycan
oligosaccharide
unambiguous structure
anti-Fxase
Optimization of P2Y(12) Antagonist Ethyl 6-(4-((Benzylsulfonyl)carbarnoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate (AZD1283) Led to the Discovery of an Oral Antiplatelet Agent with Improved Druglike Properties
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 3088-3106
作者:
Kong, Deyu
;
Xue, Tao
;
Guo, Bin
;
Cheng, Jianjun
;
Liu, Shunyin
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
Clopidogrel-associated genetic variants on inhibition of platelet activity and clinical outcome for acute coronary syndrome patients
期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2019, 卷号: 124, 期号: 1
作者:
Li, Xiaoye
;
Wang, Zi
;
Wang, Qibing
;
Xu, Qing
;
Lv, Qianzhou
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/12/05
clopidogrel
genetic variants
platelet activity
major adverse cardiovascular events
Prediction of Ticagrelor and its Active Metabolite in Liver Cirrhosis Populations Using a Physiologically Based Pharmacokinetic Model Involving Pharmacodynamics
期刊论文
JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 108, 期号: 8
作者:
Zhang, Min
;
You, Xiang
;
Ke, Meng
;
Jiao, Zheng
;
Wu, Hongwei
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/05
ticagrelor
active metabolite
physiologically based pharmacokineticmodel
liver cirrhosis populations
inhibition of platelet aggregation
Pharmacological inhibition of S6K1 facilitates platelet activation by enhancing Akt phosphorylation
期刊论文
PLATELETS, 2019, 卷号: 30, 期号: 2
作者:
Gao, Wen
;
Wang, Kemin
;
Zhang, Lin
;
Li, Jian
;
Liu, Junling
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
PDK1
platelet activation
signaling pathway
Targeting Purinergic Receptor P2Y2 Prevents the Growth of Pancreatic Ductal Adenocarcinoma by Inhibiting Cancer Cell Glycolysis
期刊论文
CLINICAL CANCER RESEARCH, 2019, 卷号: 25, 页码: 1318-1330
作者:
Hu, Li-Peng
;
Zhang, Xiao-Xin
;
Jiang, Shu-Heng
;
Tao, Ling-Ye
;
Li, Qing
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/12/02
adenosine triphosphate
ar c118925xx
gemcitabine
glucose transporter 1
hypoxia inducible factor 1alpha
Myc protein
platelet derived growth factor beta receptor
platelet derived growth factor receptor
protein kinase Yes
purinergic P2Y receptor antagonist
purinergic P2Y2 receptor
unclassified drug
Yes1 protein, Akt signaling
animal experiment
animal model
animal tissue
Article
cancer inhibition
cancer prognosis
cancer staging
controlled study
drug potentiation
glycolysis
human
human cell
human tissue
inflammation
lymph node metastasis
male
mouse
mouse model
nonhuman
overall survival
pancreas adenocarcinoma
pancreatic ductal carcinoma cell line
Pi3K/Akt signaling
priority journal
RNA sequence
tumor classification
tumor differentiation
tumor microenvironment
tumor volume
tumor xenograft
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