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浏览/检索结果: 共5条，第1-5条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Design and synthesis of highly selective pyruvate dehydrogenase complex E1 inhibitors as bactericides 期刊论文 Bioorganic and Medicinal Chemistry, 2018, 卷号: 26, 期号: 1, 页码: 84-95 作者:  Zhou, Yuan;  Zhang, Shasha;  He, Hongwu*;  Jiang, Wen;  Hou, Leifeng 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/23 PDHc-E1 inhibitor  Acylhydrazone  Antibacterial  Enzyme-selectivity  Molecular docking   Design and optimization of N-acylhydrazone pyrimidine derivatives as E. coli PDHc E1 inhibitors: Structure-activity relationship analysis, biological evaluation and molecular docking study 期刊论文 Bioorganic and Medicinal Chemistry, 2017, 卷号: 25, 期号: 20, 页码: 5652-5661 作者:  He, Haifeng;  Xia, Hongying;  Xia, Qin;  Ren, Yanliang;  He, Hongwu* 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/23 ThDP  E. coli PHDc E1  Enzyme-selective  Molecular docking   Rational design, synthesis and biological evaluation of 1,3,4-oxadiazole pyrimidine derivatives as novel pyruvate dehydrogenase complex E1 inhibitors 期刊论文 Bioorganic and Medicinal Chemistry, 2016, 卷号: 24, 期号: 8, 页码: 1879-1888 作者:  He, Haifeng;  Wang, Wei;  Zhou, Yuan;  Xia, Qin;  Ren, Yanliang 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/23 Antibacterial activity  PDHc-E1 inhibitor  Cyanobacteria  1,3,4-Oxadiazole   Design, synthesis and molecular modeling of novel N-acylhydrazone derivatives as pyruvate dehydrogenase complex E1 inhibitors 期刊论文 Bioorganic and Medicinal Chemistry, 2014, 卷号: 22, 期号: 1, 页码: 89-94 作者:  He, Jun-Bo;  Feng, Ling-Ling;  Li, Jing;  Tao, Rui-Juan;  Ren, Yan-Liang 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/23 PDHc-E1 inhibitors  N-Acylhydrazone derivatives  Synthesis  Molecular modeling   Design, synthesis and biological evaluation of novel 2-methylpyrimidine-4- ylamine derivatives as inhibitors of Escherichia coli pyruvate dehydrogenase complex E1 期刊论文 Bioorganic and Medicinal Chemistry, 2012, 卷号: 20, 期号: 5, 页码: 1665-1670 作者:  He, Junbo;  Feng, Lingling;  Li, Jing;  Tao, Ruijuan;  Wang, Fang 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/23 2-Methylpyrimidine-4-ylamine  PDHc E1 inhibitor  Antifungal activity  Click chemistry