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Novel Tadalafil Derivatives Ameliorates Scopolamine-Induced Cognitive Impairment in Mice via Inhibition of Acetyicholinesterase (AChE) and Phosphodiesterase 5 (PDE5) 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2018, 卷号: 9, 期号: 7, 页码: 1625-1636
作者:  Ni, Wei;  Wang, Huan;  Li, Xiaokang;  Zheng, Xinyu;  Wang, Manjiong
收藏  |  浏览/下载:43/0  |  提交时间:2019/01/08
Design, Synthesis, and Biological Evaluation of Orally Available First-Generation Dual-Target Selective Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) for the Treatment of Alzheimer's Disease 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2018, 卷号: 9, 期号: 2, 页码: 328-345
作者:  Mao, Fei;  Wang, Huan;  Ni, Wei;  Zheng, Xinyu;  Wang, Manjiong
收藏  |  浏览/下载:56/0  |  提交时间:2019/01/08
Flavonoid glycosides isolated from Epimedium brevicornum and their estrogen biosynthesis-promoting effects 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 7760(1-12)
作者:  Liu, CL;  Li, F;  Du, BW;  Lu, DF;  Wu, WX
收藏  |  浏览/下载:34/0  |  提交时间:2018/08/28
Flavonoid glycosides isolated from Epimedium brevicornum and their estrogen biosynthesis-promoting effects 期刊论文
Scientific Reports, 2017, 卷号: 7, 期号: X, 页码: e7760
作者:  Li F;  Du BW;  Wang L;  Pu WC;  Liu CL
收藏  |  浏览/下载:18/0  |  提交时间:2017/08/14
Characterization of TPN729 metabolites in humans using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2016, 卷号: 117, 页码: 217-226
作者:  Zhu, Yunting;  Li, Liang;  Deng, Pan;  Chen, Xiaoyan;  Zhong, Dafang
收藏  |  浏览/下载:23/0  |  提交时间:2019/01/08
The Selectivity and Potency of the New PDE5 Inhibitor TPN729MA 期刊论文
JOURNAL OF SEXUAL MEDICINE, 2013, 卷号: 10, 期号: 11, 页码: 2790-2797
作者:  Wang, Zhen;  Zhu, Difeng;  Yang, Xiaochun;  Li, Jianfeng;  Jiang, Xiangrui
收藏  |  浏览/下载:24/0  |  提交时间:2019/01/08
Exploration of the 5-bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 17, 页码: 4944-4947
作者:  Gong, Xudong;  Wang, Guan;  Ren, Jing;  Liu, Zheng;  Wang, Zhen
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08
嘧啶酮类膦酸二酯酶抑制剂的设计、合成及生物活性评价和2-脱氧-2-氟-2-碳-甲基-D-核糖-γ-内酯类衍生物的合成研究 学位论文
硕士, 北京: 中国科学院大学, 2013
作者:  公绪栋
收藏  |  浏览/下载:86/0  |  提交时间:2013/05/31
Exploration of the 5-bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 17, 页码: 4944-4947
作者:  Gong Xudong;  Wang Guan;  Ren Jing;  Liu Zheng;  Wang Zhen
收藏  |  浏览/下载:36/0  |  提交时间:2013/11/07
First Syntheses of Lorneic Acids A and B with Potential PDE5 Inhibition Activity 期刊论文
SYNLETT, 2012, 期号: 4
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收藏  |  浏览/下载:3/0  |  提交时间:2014/12/05


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