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Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors 期刊论文
PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664
作者:  Xu, Jianghong;  Hu, Yuanyuan;  Liu, Xiaoqi;  Gao, Anhui;  Gao, Lixin
收藏  |  浏览/下载:37/0  |  提交时间:2021/12/01
Isocitrate Dehydrogenase 2 Inhibitors for the Treatment of Hematologic Malignancies: Advances and Future Opportunities 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21
作者:  Huang, Feng;  Tian, Tian;  Wu, Yizhe;  Che, Jinxin;  Yang, Haiyan
收藏  |  浏览/下载:17/0  |  提交时间:2021/06/15
Pharmacological characterization of TQ05310, a potent inhibitor of isocitrate dehydrogenase 2 R140Q and R172K mutants 期刊论文
CANCER SCIENCE, 2019, 页码: 9
作者:  Gao, Mingzhao;  Zhu, Hongmei;  Fu, Li;  Li, Yun;  Bao, Xubin
收藏  |  浏览/下载:17/0  |  提交时间:2020/07/01
AG-221  IDH2  leukemia  R140Q  R172K  
Discovery of DC_H31 as potential mutant IDH1 inhibitor through NADPH-based high throughput screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3229-3236
作者:  Duan, Zhe;  Liu, Jingqiu;  Niu, Liping;  Wang, Jun;  Feng, Mingqian
收藏  |  浏览/下载:55/0  |  提交时间:2020/07/01
Activation of AhR with nuclear IKK alpha regulates cancer stem-like properties in the occurrence of radioresistance 期刊论文
CELL DEATH & DISEASE, 2018, 卷号: 9
作者:  Yan, Bin;  Liu, Shuang;  Shi, Ying;  Liu, Na;  Chen, Ling
收藏  |  浏览/下载:108/0  |  提交时间:2019/01/08
Potent immunosuppressive effects of the oncometabolite R-2-hydroxyglutarate 期刊论文
2018, 卷号: 7, 期号: 12
作者:  Galluzzi, Lorenzo;  Kroemer, Guido
收藏  |  浏览/下载:1/0  |  提交时间:2020/01/03
Hypotaurine evokes a malignant phenotype in glioma through aberrant hypoxic signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 12, 页码: 15200-15214
作者:  Gao, Peng;  Yang, Chunzhang;  Nesvick, Cody L.;  Feldman, Michael J.;  Sizdahkhani, Saman
收藏  |  浏览/下载:28/0  |  提交时间:2019/06/20
Oncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents 期刊论文
CELL REPORTS, 2015, 卷号: 13, 期号: 11
作者:  Wang, Pu;  Wu, Jing;  Ma, Shenghong;  Zhang, Lei;  Yao, Jun
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/19
A whole-cell electrochemical biosensing system based on bacterial inward electron flow for fumarate quantification 期刊论文
BIOSENSORS & BIOELECTRONICS, 2015, 卷号: 68, 页码: 34-40
作者:  Si, Rong-Wei[1];  Zhai, Dan-Dan[2];  Liao, Zhi-Hong[3];  Gao, Lu[4];  Yong, Yang-Chun[5]
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/24
Alterations of metabolic genes and metabolites in cancer 期刊论文
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 2012, 卷号: 23, 期号: 4
作者:  Oermann, Eric K.;  Wu, Jing;  Guan, Kun-Liang;  Xiong, Yue
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/19


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