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Nuclear lamina erosion-induced resurrection of endogenous retroviruses underlies neuronal aging 期刊论文
CELL REPORTS, 2023, 卷号: 42, 期号: 6, 页码: 31
作者:  Zhang, Hui;  Li, Jiaming;  Yu, Yang;  Ren, Jie;  Liu, Qiang
收藏  |  浏览/下载:15/0  |  提交时间:2023/11/17
Potency and pharmacokinetics of GS-441524 derivatives against SARS-CoV-2 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 46, 期号: 9, 页码: 1-12
作者:  Wei, DB (Wei, Daibao);  Hu, TW (Hu, Tianwen);  Zhang, YM (Zhang, Yumin);  Zheng, W (Zheng, Wei);  Xue, HT (Xue, Haitao)
收藏  |  浏览/下载:28/0  |  提交时间:2021/10/14
Recent progress in HIV-1 inhibitors targeting the entrance channel of HIV-1 non-nucleoside reverse transcriptase inhibitor binding pocket 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 174
作者:  Gu, Shuang-Xi;  Xiao, Ting;  Zhu, Yuan-Yuan;  Liu, Gen-Yan;  Chen, Fen-Er
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/05
NME4 may enhance non-small cell lung cancer progression by overcoming cell cycle arrest and promoting cellular proliferation 期刊论文
MOLECULAR MEDICINE REPORTS, 2019, 卷号: 20, 期号: 2
作者:  Wang, Wenqian;  Dong, Ming;  Cui, Jie;  Xu, Fei;  Yan, Chen
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/05
Synthesis and biological evaluation of dihydroquinazoline-2-amines as potent non-nucleoside reverse transcriptase inhibitors of wild-type and mutant HIV-1 strains 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 176
作者:  Jin, KaiJun;  Sang, YaLi;  Han, Sheng;  De Clercq, Erik;  Pannecouque, Christophe
收藏  |  浏览/下载:25/0  |  提交时间:2019/12/05
Exploiting the Tolerant Region I of the Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Binding Pocket: Discovery of Potent Diarylpyrimidine-Typed HIV-1 NNRTIs against Wild-Type and E138K Mutant Virus with Significantly Improved Water Solubility and Favorable Safety Profiles 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 4, 页码: 2083-2098
作者:  Huang, Boshi;  Chen, Wenmin;  Zhao, Tong;  Li, Zhenyu;  Jiang, Xiangyi
收藏  |  浏览/下载:15/0  |  提交时间:2019/12/11
The Journey of HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) from Lab to Clinic 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4851-4883
作者:  Namasivayam, Vigneshwaran;  Vanangamudi, Murugesan;  Kramer, Victor G.;  Kurup, Sonali;  Zhan, Peng
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/11
Discovery of piperidine-substituted thiazolo[5,4-d]pyrimidine derivatives as potent and orally bioavailable HIV-1 non-nucleoside reverse transcriptase inhibitors 期刊论文
Communications Chemistry, 2019, 卷号: 2, 期号: 1
作者:  Kang D.;  Zhao T.;  Wang Z.;  Feng D.;  Zhang H.
收藏  |  浏览/下载:10/0  |  提交时间:2019/12/11
Discovery of potent HIV-1 non-nucleoside reverse transcriptase inhibitors by exploring the structure-activity relationship of solvent-exposed regions I 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 93, 期号: 4, 页码: 430-437
作者:  Kang, Dongwei;  Wang, Zhao;  Chen, Meng;  Feng, Da;  Wu, Gaochan
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/11
Identification of Dihydrofuro[3,4-d]pyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 3, 页码: 1484-1501
作者:  Kang, Dongwei;  Zhang, Heng;  Wang, Zhao;  Zhao, Tong;  Ginex, Tiziana
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/11


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