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科研机构
上海药物研究所 [4]
山东大学 [4]
内容类型
期刊论文 [8]
发表日期
2019 [1]
2018 [2]
2016 [2]
2015 [2]
2012 [1]
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Exploration of the structure-activity relationship and druggability of novel oxazolidinone-based compounds as Gram-negative antibacterial agents
期刊论文
ARCHIV DER PHARMAZIE, 2019, 页码: 13
作者:
Ding, Shi
;
Ji, Jing-Chao
;
Zhang, Ming-Juan
;
Yang, Yu-She
;
Wang, Rui
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
antibacterial activity
oxazolidine
QSAR
Design, synthesis and structure-activity relationship evaluation of novel LpxC inhibitors as Gram-negative antibacterial agents
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 2, 页码: 94-102
作者:
Ding, Shi
;
Dai, Rui-Yang
;
Wang, Wen-Ke
;
Cao, Qiao
;
Lan, Le-Fu
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Gram-negative bacteria infection
LpxC inhibitor
Structure-activity relationship
Zinc binding group
Liver microsomal stability
Recent process in the inhibitors of UDP-3-o-(R-3-hydroxyacyl)-n-acetylglucosamine deacetylase (LpxC) against gram-negative bacteria
期刊论文
Mini-Reviews in Medicinal Chemistry, 2018, 卷号: 18, 期号: 4, 页码: 310-323
作者:
Liu F.
;
Ma S.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
Anti-bacterial agent
Biosynthesis
Gram-negative bacterial
Lipid A biosynthesis
LpxC inhibitors
UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC)
Anti-Gram-negative bacteria new target: UDP-3-O-(R-3-hydroxyacyl)-N-acetylglucosamine deacetylase (LpxC) and its inhibitors.
期刊论文
Mini reviews in medicinal chemistry, 2016
作者:
Liu, Fang
;
Ma, Shutao
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/16
Recent Process in the Inhibitors of UDP-3-O-(R-3-hydroxyacyl)-Nacetylglucosamine Deacetylase (LpxC) Against Gram-Negative Bacteria.
期刊论文
Mini reviews in medicinal chemistry, 2016, 卷号: 18, 期号: 4
作者:
Liu, Fang
;
Ma, Shutao
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/17
Design, synthesis and biological evaluation of LpxC inhibitors with novel hydrophilic terminus
期刊论文
CHINESE CHEMICAL LETTERS, 2015, 卷号: 26, 期号: 6, 页码: 763-767
作者:
Ding, Shi
;
Wang, Wen-Ke
;
Cao, Qiao
;
Chu, Wen-Jing
;
Lan, Le-Fu
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
LpxC
CHIR-090
Kojic acid derivatives
Methylsulfone derivatives
Metabolic stability
designsynthesisandbiologicalevaluationoflpxcinhibitorswithnovelhydrophilicterminus
期刊论文
chinesechemicalletters, 2015, 卷号: 26, 期号: 6, 页码: 763
作者:
Ding Shi
;
Wang Wenke
;
Cao Qiao
;
Chu Wenjing
;
Lan Lefu
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
GRAM-NEGATIVE INFECTIONS
ANTIBACTERIAL AGENTS
ANTIBIOTIC-ACTIVITY
DEACETYLASE LPXC
BIOSYNTHESIS
ENDOTOXIN
LpxC
CHIR-090
Kojic acid derivatives
Methylsulfone derivatives
Metabolic stability
UDP-3-O-(R-3-hydroxymyristoyl)-N-Acetylglucosamine Deacetylase (LpxC) Inhibitors: A New Class of Antibacterial Agents
期刊论文
CURRENT MEDICINAL CHEMISTRY, 2012, 卷号: 19, 期号: 13, 页码: 2038-2050
作者:
Zhang, J.
;
Zhang, L.
;
Li, X.
;
Xu, W.
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  |  
浏览/下载:4/0
  |  
提交时间:2019/12/23
Gram-negative bacteria
MDR
lipid A
biosynthesis
LpxC
Structure
FtsH
LpxC Inhibitors
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