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Baicalin Ameliorates Radiation-Induced Lung Injury by Inhibiting the CysLTs/CysLT1 Signaling Pathway
期刊论文
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2022, 卷号: 2022
作者:
Bao, Wu-An
;
Wang, Yue-Zhen
;
Zhu, Xiang
;
Lin, Juan
;
Fan, Ju-Fen
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2022/12/23
BLT1 in dendritic cells promotes Th1/Th17 differentiation and its deficiency ameliorates TNBS-induced colitis
期刊论文
CELLULAR & MOLECULAR IMMUNOLOGY, 2018, 卷号: 15, 期号: 12, 页码: 1047-1056
作者:
Zhou, Jinfeng
;
Lai, Weiming
;
Yang, Wanjie
;
Pan, Juping
;
Shen, Hu
收藏
  |  
浏览/下载:161/0
  |  
提交时间:2019/01/08
Diesel exhaust particle promotes tumor lung metastasis via the induction of BLT1-mediated neutrophilic lung inflammation
期刊论文
CYTOKINE, 2018, 卷号: 111
作者:
Li, Wenjing
;
Liu, Ting
;
Xiong, Yingluo
;
Lv, Jiaoyan
;
Cui, Xinyi
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Diesel exhaust particle
Leukotriene B4-BLT1 axis
Neutrophil
Lung inflammation
Metastasis
Expression of cysteinyl leukotriene receptor GPR17 in eosinophilic and non-eosinophilic chronic rhinosinusitis with nasal polyps
期刊论文
2018, 卷号: 36, 期号: 2, 页码: 93
作者:
Chen, Kun[1]
;
Yu, Zhijian[2]
;
Yang, Jun[1]
;
Li, Huabin[1]
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/10
Drug Repurposing of Histone Deacetylase Inhibitors That Alleviate Neutrophilic Inflammation in Acute Lung Injury and Idiopathic Pulmonary Fibrosis via Inhibiting Leukotriene A4 Hydrolase and Blocking LTB4 Biosynthesis
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 5
作者:
Lu, Weiqiang
;
Yao, Xue
;
Ouyang, Ping
;
Dong, Ningnin
;
Wu, Dang
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
The leukotriene B-4-leukotriene B-4 receptor axis promotes cisplatin-induced acute kidney injury by modulating neutrophil recruitment
期刊论文
KIDNEY INTERNATIONAL, 2017, 卷号: 92, 期号: 1
作者:
Deng, Bo
;
Lin, Yuli
;
Ma, Shuai
;
Zheng, Yin
;
Yang, Xuguang
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
acute kidney injury
cisplatin nephrotoxicity
leukotriene B-4
leukotriene B-4 receptor 1
neutrophils
Drug Repurposing of Histone Deacetylase Inhibitors That Alleviate Neutrophilic Inflammation in Acute Lung Injury and Idiopathic Pulmonary Fibrosis via Inhibiting Leukotriene A4 Hydrolase and Blocking LTB4 Biosynthesis
期刊论文
Journal of Medicinal Chemistry, 2017, 卷号: Vol.60 No.5, 页码: 1817-1828
作者:
Lu, W.
;
Yao, X.
;
Ouyang, P.
;
Dong, N.
;
Wu, D.
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/02/25
Renoprotective approaches and strategies in acute kidney injury
期刊论文
Pharmacology and Therapeutics, 2016, 卷号: 163, 页码: 58-73
作者:
Yang, Yuan
;
Song, Meifang
;
Liu, Yu
;
Liu, Hong
;
Sun, Lin
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/12/03
ACTH
Adrenocorticotropic hormone
AIF
Apoptosis inducing factor
AKI
Acute kidney injury
BMSC
Bone marrow derived stem cells
CIN
Contrast-induced nephropathy
COMP-Ang1
Cartilage oligomeric matrix protein-angiopoietin-1
CysLT1R
Cysteinyl leukotriene-1 receptor
DMARD
Disease-modifying antirheumatic drugs
eNOS
Endothelial nitric oxide synthase
eEPCs
Endothelial progenitor cells
HDAC
Histone deacetylase
HSPC
Hematopoietic stem and progenitor cells
IRI
Ischemia–reperfusion injury
ICAM-1
Intercellular adhesion molecule-1
JNK
c-Jun N-terminal kinase
KIF3B
Kinesin family member 3B
KIM-1
Kidney injury molecule 1
MAPK
Mitogen-activated protein kinase
MCP-1
Monocyte chemotactic protein-1
α-MSH
Alpha-melanocyte-stimulating hormone
MFG-E8
Milk fat globule-epidermal growth factor-factor VIII
MPT
Mitochondrial permeability transition
MSCs
Mesenchymal stem cells
NGAL
Neutrophil gelatinase-associated lipocalin
MDM2
Murine double minute-2
MMP-2
Matrix metallopeptidase 2
mTOR
Mammalian target of rapamycin
PI3K
Phosphatidylinositol-3 kinase
PACAP
Pituitary adenylate cyclase activating polypeptide
RAAS
Renin–angiotensin–aldosterone system
RANTES
Regulated upon activation normal T-cell expressed and secreted
RIP1
Receptor-interacting protein 1
TNF-α
Tumor necrosis factor-alpha
TWEAK
TNF-like weak inducer of apoptosis
VDRA
Vitamin D receptor agonist
Acute kidney injury
Kidney protection
Kidney repair
Renoprotection
Ischemia–reperfusion
Nephrotoxicity
Structural optimization and biological evaluation of 1,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase
期刊论文
ACTA PHARMACEUTICA SINICA B, 2016, 卷号: 6, 期号: 1, 页码: 32-45
作者:
Zhou, Yu
;
Liu, Jun
;
Zheng, Mingyue
;
Zheng, Shuli
;
Jiang, Chunyi
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
5-Lipoxygenase
5-LOX inhibitors
Pyrazole derivatives
Leukotrienes-related diseases
In vivo
Benzo-fuse heterocyle
Ischemic incults
Brain inflammation
Cytotoxic polyprenylated acylphloroglucinol derivatives from Hypericum henryi
期刊论文
TETRAHEDRON, 2015, 卷号: 71, 期号: 43, 页码: 8315-8319
作者:
Zhang,Jing-Jing
;
Yang,Xing-Wei
;
Ma,Jun-Zeng
;
Ye,Ye
;
Shen,Xiao-Ling
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2016/01/19
Polyprenylated acylphloroglucinol
Hypericum henryi
Hyperhenones A-F
Antitumor
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