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上海药物研究所 [4]
北京大学 [3]
中南大学 [3]
复旦大学上海医学院 [3]
上海生物化学与细胞生... [3]
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期刊论文 [35]
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浏览/检索结果:
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Discovery of DC_H31 as potential mutant IDH1 inhibitor through NADPH-based high throughput screening
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3229-3236
作者:
Duan, Zhe
;
Liu, Jingqiu
;
Niu, Liping
;
Wang, Jun
;
Feng, Mingqian
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/07/01
IDH1 mutation
High-throughput screening
Pan-inhibitor
2-HG
Gliomas
Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancy
期刊论文
2018, 卷号: 128, 期号: 12, 页码: 5383-5398
作者:
Zhang, Peng
;
He, Fuhong
;
Bai, Jie
;
Yamamoto, Shohei
;
Chen, Shi
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
Epigenetics
Hematology
Leukemias
Stem cells
Expression of the fetal hematopoiesis regulator FEV indicates leukemias of prenatal origin
期刊论文
LEUKEMIA, 2017, 卷号: 31, 期号: 5
作者:
Liu, T-H
;
Tang, Y-J
;
Huang, Y.
;
Wang, L.
;
Guo, X-L
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
Expression of the Fetal Hematopoiesis Regulator FEV Indicates Leukemias of Prenatal Origin
期刊论文
Leukemia, 2017, 卷号: 31, 期号: 5, 页码: 1079-1086
作者:
Tian-Hui Liu
;
Yan-Jing Tang
;
Yan Huang
;
Wang L(王璐)
;
Xiao-Lin Guo
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2018/07/05
Identification of Novel Disruptor of Telomeric Silencing 1-like (DOT1L) Inhibitors through Structure-Based Virtual Screening and Biological Assays
期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2016, 卷号: 56, 期号: 3, 页码: 527-534
作者:
Chen, Shijie
;
Li, Linjuan
;
Chen, Yantao
;
Hu, Junchi
;
Liu, Jingqiu
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Exploration of binding affinity and selectivity of brucine with G-quadruplex in the c-myb proto-oncogene by electrospray ionization mass spectrometry
期刊论文
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2016, 卷号: 30, 期号: 3, 页码: 407-414
作者:
Zhou, Jiang
;
Li, Huihui
;
Hai, Jinhui
;
Yuan, Gu
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/06/20
The formation and characteristics of the i-motif structure within the promoter of the c-myb proto-oncogene
期刊论文
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2016
Li, Huihui
;
Hai, Jinhui
;
Zhou, Jiang
;
Yuan, Gu
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/12/03
i-Motif
C-myb
Circular dichroism
Electrospray ionization mass spectrometry
Conformational switching
Molecular crowding
G-QUADRUPLEX DNA
MASS-SPECTROMETRY
CIRCULAR-DICHROISM
GENE-EXPRESSION
SEQUENCES
ONCOGENE
BINDING
SWITCH
OLIGODEOXYNUCLEOTIDES
CONFORMATION
Exploration of binding affinity and selectivity of brucine with G-quadruplex in the c-myb proto-oncogene by electrospray ionization mass spectrometry
期刊论文
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2016
Li, Huihui
;
Hai, Jinhui
;
Zhou, Jiang
;
Yuan, Gu
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/12/03
HIV-1 INTEGRASE INHIBITORS
DIMERIC G-QUADRUPLEXES
DNA G-QUADRUPLEX
PROMOTER REGION
ESI-MS
EXPRESSION
RECOGNITION
ONCOGENE
GENE
DIFFERENTIATION
Simultaneous targeting of PI3K delta and a PI3K delta-dependent MEK1/2-Erk1/2 pathway for therapy in pediatric B-cell acute lymphoblastic leukemia
期刊论文
ONCOTARGET, 2014, 卷号: 5, 期号: 21, 页码: 10732-10744
作者:
Wang, Xiang
;
Zhang, Xi
;
Li, Ben-shang
;
Zhai, Xiaowen
;
Yang, Zhuo
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
PI-3Kdelta inhibitor
MAPK
B cell acute lymphocytic leukemia
target therapy
A novel self-lipid antigen targets human T cells against CD1c(+) leukemias
期刊论文
JOURNAL OF EXPERIMENTAL MEDICINE, 2014, 卷号: 211, 期号: 7, 页码: 1360-1374
作者:
Lepore, Marco
;
de Lalla, Claudia
;
Gundimeda, S. Ramanjaneyulu
;
Gsellinger, Heiko
;
Consonni, Michela
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2014/10/11
ACUTE MYELOID-LEUKEMIA
NKT CELLS
MASS-SPECTROMETRY
MYCOBACTERIUM-TUBERCULOSIS
ELECTROSPRAY-IONIZATION
LYSOPHOSPHATIDIC ACID
DONOR LYMPHOCYTES
IMMUNE-RESPONSES
CANCER
GLYCOLIPIDS
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