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上海药物研究所 [136]
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复旦大学上海医学院 [17]
大连化学物理研究所 [15]
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期刊论文 [377]
学位论文 [9]
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Molecular imaging-guided extracellular vesicle-based drug delivery for precise cancer management: Current status and future perspectives
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2023, 卷号: 362, 页码: 97-120
作者:
Cheng, Zhongquan
;
Shang, Jihuan
;
Wang, Huarong
;
Yu, Leyi
;
Yuan, Zhu
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/11/16
Extracellular vesicles
Molecular imaging
Cancer
Diagnosis
Therapy
Loratadine oral bioavailability enhancement via solid dispersion loaded oro-dispersible films: Formulation, characterization and pharmacokinetics
期刊论文
COLLOIDS AND SURFACES B-BIOINTERFACES, 2023, 卷号: 230
作者:
Islam, Nayyer
;
Khan, Naveed Ullah
;
Razzaq, Anam
;
Menaa, Farid
;
Khan, Zaheer Ullah
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/11/17
Loratadine
Solid dispersion
Oro-dispersible film
Bioavailability
Urticaria
[
68
Ga]Ga-AUNP-12 PET imaging to assess the PD-L1 status in preclinical and first-in-human study
期刊论文
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2023, 页码: 11
作者:
Zhou, Ming
;
Xiang, Shijun
;
Zhao, Yajie
;
Tang, Yongxiang
;
Yang, Jinhui
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/11/16
PD-1/PD-L1
Immune checkpoints
PET/CT imaging
Immunotherapy
Optimization of ODAP-Urea-based dual-modality PSMA targeting probes for sequential PET-CT and optical imaging
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 66, 页码: 10
作者:
Li, Yuan
;
Duan, Xiaojiang
;
Xu, Hongchuang
;
Zhang, Jingming
;
Zhou, Haoxi
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/07/25
Prostate cancer
Prostate-specific membrane antigen (PSMA)
Dual-modality imaging
PET imaging
Optical imaging
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
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  |  
浏览/下载:62/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Dong, Ying
;
Tang, Bi-xi
;
Wang, Qi
;
Zhou, Li-wei
;
Li, Cong
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2022/01/04
idiopathic pulmonary fibrosis
DDRs
kinase inhibitor
indazole derivatives
XBLJ-13
nintedanib
bleomycin-induced pulmonary fibrosismouse model
Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14
作者:
He, Yu-Long
;
Chen, Meng-Ting
;
Wang, Ting
;
Zhang, Ming-Ming
;
Li, Ying-Xia
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2021/11/04
Type 2 diabetes mellitus
Dual FABP4/5 inhibitors
Anti-lipolytic and anti-inflammatory effects
Metabolic stability
Anti-diabetic activities
Define Mesenchymal Stem Cell from Its Fate: Biodisposition of Human Mesenchymal Stem Cells in Normal and Concanavalin A-Induced Liver Injury Mice
期刊论文
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2021, 卷号: 379, 期号: 2, 页码: 125-133
作者:
Han, Li
;
Ma, Chenhui
;
Peng, Huige
;
Wu, Zhitao
;
Xu, Huiming
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/01/04
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
Itraconazole and rifampicin, as CYP3A modulators but not P-gp modulators, affect the pharmacokinetics of almonertinib and active metabolite HAS-719 in healthy volunteers
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Liu, Lu
;
Li, Wei
;
Yang, Le
;
Guo, Zi-tao
;
Xue, Hao
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2021/08/17
almonertinib
itraconazole
rifampicin
drug metabolism
drug interaction
CYP3A
P-gp
pharmacokinetics
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