×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
大连化学物理研究所 [21]
上海药物研究所 [9]
复旦大学上海医学院 [9]
厦门大学 [3]
中南大学 [3]
广州生物医药与健康研... [1]
更多...
内容类型
期刊论文 [34]
会议论文 [17]
学位论文 [1]
发表日期
2021 [1]
2018 [2]
2017 [1]
2016 [2]
2015 [4]
2014 [7]
更多...
学科主题
物理化学 [10]
Biochemist... [1]
Biophysics [1]
药物分析学 [1]
药物化学 [1]
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共52条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Wu, Ya-li
;
Xue, Ya-ru
;
Guo, Zi-tao
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/17
furmonertinib (alflutinib
AST2818)
quantitative proteomics
sandwich-cultured human hepatocytes
CYP3A4 inducer and inhibitor strongly affect the pharmacokinetics of triptolide and its derivative in rats
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 8, 页码: 1386-1392
作者:
Xu, Ye
;
Zhang, Yi-fan
;
Chen, Xiao-yan
;
Zhong, Da-fang
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
triptolide
(5R)-5-hydroxytriptolide
CYP3A4
ritonavir
dexamethasone
pharmacokinetics
immunosuppressant
traditional Chinese medicine
cyp3a4inducerandinhibitorstronglyaffectthepharmacokineticsoftriptolideanditsderivativeinrats
期刊论文
actapharmacologicasinica, 2018, 卷号: 039, 期号: 008, 页码: 1386
作者:
Xu Ye
;
Zhang Yifan
;
Chen Xiaoyan
;
Zhong Dafang
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/07/01
衍生物
老鼠
CYP3a
风湿性关节炎
新陈代谢
相互作用
细胞色素
P450
Inhibition of human CYP3A4 and CYP3A5 enzymes by gomisin C and gomisin G, two lignan analogs derived from Schisandra chinensis
期刊论文
FITOTERAPIA, 2017, 卷号: 119, 页码: 26-31
作者:
Zhao, Jin
;
Sun, Tao
;
Wu, Jing-Jing
;
Cao, Yun-Feng
;
Fang, Zhong-Ze
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2017/10/29
Gomisin c
Gomisin g
Cyp3a4
Cyp3a5
Inhibition
Herb-drug Interactions
Gomisin A is a Novel Isoform-Specific Probe for the Selective Sensing of Human Cytochrome P450 3A4 in Liver Microsomes and Living Cells
期刊论文
aaps journal, 2016, 卷号: 18, 期号: 0, 页码: 134
作者:
Wu JJ(吴敬敬)
;
Ge GB(葛广波)
;
He YQ(何芋岐)
;
Wang P(王平)
;
Dai ZR(戴子茹)
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2016/11/24
In Vitro and in Vivo Inhibitory Effects of Glycyrrhetinic Acid in Mice and Human Cytochrome P450 3A4.
期刊论文
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2016, 卷号: 13, 期号: 1, 页码: 84
作者:
Lv, Qiao-Li
;
Wang, Gui-Hua
;
Chen, Shu-Hui
;
Hu, Lei
;
Zhang, Xue
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
IC50
cytochrome P450 3A4
glycyrrhetinic acid
herb-drug interaction
inhibitory effect
Inhibition of human cytochrome P450 enzymes by licochalcone A, a naturally occurring constituent of licorice
期刊论文
toxicology in vitro, 2015, 卷号: 29, 期号: 7, 页码: 1569-1576
作者:
He, Wei
;
Wu, Jing-Jing
;
Ning, Jing
;
Hou, Jie
;
Xin, Hong
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2015/11/17
Licochalcone A (LCA)
Human liver microsomes (HLMs)
Cytochrome P450 enzymes (CYPs)
Inhibition
Herb-drug interactions (HDIs)
A Mechanism-Based Model for the Prediction of the Metabolic Sites of Steroids Mediated by Cytochrome P450 3A4
期刊论文
international journal of molecular sciences, 2015, 卷号: 16, 期号: 7, 页码: 14677-14694
作者:
Dai, Zi-Ru
;
Ai, Chun-Zhi
;
Ge, Guang-Bo
;
He, Yu-Qi
;
Wu, Jing-Jing
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2015/11/17
CYP3A4
steroids
metabolic site
mechanism-based prediction
activation energy
Inhibitory effect of salvianolate on human cytochrome P450 3A4 in vitro involving a noncompetitive manner
期刊论文
International Journal of Clinical and Experimental Medicine, 2015, 卷号: 8, 期号: 9, 页码: 15549-15555
作者:
Qin, Chong-Zhen
;
Ren, Xian
;
Zhou, Hong-Hao
;
Mao, Xiao-Yuan
;
Liu, Zhao-Qian*
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/03
CYP3A4
Salvianolate
drug-drug interaction
human liver microsomes
noncompetitive inhibition
Mechanism-based inhibition of Alantolactone on human cytochrome P450 3A4 in vitro and activity of hepatic cytochrome P450 in mice
期刊论文
Journal of ethnopharmacology, 2015, 卷号: 168, 页码: 146-149
作者:
Qin, Chong-Zhen
;
Lv, Qiao-Li
;
Wu, Na-Yiyuan
;
Cheng, Lin
;
Chu, Yun-Chen
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
Alantolactone
Alantolactone PubChem CID: 72724
CYP3A4
Drug-drug interaction
Human liver microsomes
Noncompetitive inhibition
©版权所有 ©2017 CSpace - Powered by
CSpace