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Direct mechanical exposure initiates hepatocyte proliferation
期刊论文
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13
作者:
Li, Wang
;
Wu, Yi
;
Hu, Wenhui
;
Zhou, Jin
;
Shu, Xinyu
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/01/02
Mechanotransduction
FAK
hepatic sinusoid chip
Acetaldehyde induces similar cytotoxic and genotoxic risks in BEAS-2B cells and HHSteCs: involvement of differential regulation of MAPK/ERK and PI3K/AKT pathways
期刊论文
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2023, 卷号: 30
作者:
Zhang, Jingni
;
Wang, Hongjuan
;
Chen, Huan
;
Liu, Yong
;
Wang, An
收藏
  |  
浏览/下载:123/0
  |  
提交时间:2023/11/17
Acetaldehyde
Cytotoxicity
Genotoxicity
BEAS-2B cells
HHSteCs
MAPK/ERK
PI3K/AKT
Potential adverse outcome pathways with hazard identification of organophosphate esters
期刊论文
SCIENCE OF THE TOTAL ENVIRONMENT, 2022, 卷号: 851, 页码: 13
作者:
Wang, Xiaoqing
;
Li, Fei
;
Teng, Yuefa
;
Ji, Chenglong
;
Wu, Huifeng
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/01/11
Organophosphate esters (OPEs)
Network-centric analysis
Risk assessment
Adverse outcome pathway
Quantitative weight of evidence
Numerical simulation of flow characteristics in a permeable liver sinusoid with leukocytes
期刊论文
BIOPHYSICAL JOURNAL, 2022, 卷号: 121, 期号: 23, 页码: 4666-4678
作者:
Chen, Shenbao
;
Zhu, Jingchen
;
Xue, Jian
;
Wang, Xiaolong
;
Jing, Peng
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  |  
浏览/下载:21/0
  |  
提交时间:2023/02/07
Multiscale biomechanics and mechanotransduction from liver fibrosis to cancer
期刊论文
ADVANCED DRUG DELIVERY REVIEWS, 2022, 卷号: 188, 页码: 114448
作者:
Li N(李宁)
;
Zhang XY(张晓宇)
;
Zhou J(周瑾)
;
Li W(李旺)
;
Shu XY(舒芯钰)
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/10/23
Liver tissue stiffness
Shear stress
Hydrostatic pressure
Hepatocytes
Hepatocellular carcinoma
Liver sinusoidal endothelial cells
Hepatic stellate cells
Mechanotransduction pathways
Mechanomedicine
Drug design and delivery
Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
Influence of microflow on hepatic sinusoid blood flow and red blood cell deformation
期刊论文
BIOPHYSICAL JOURNAL, 2021, 卷号: 120, 期号: 21, 页码: 4859-4873
作者:
Wang, Tianhao
;
Lv SQ(吕守芹)
;
Hao, Yinjing
;
Su, Zinan
;
Long M(龙勉)
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  |  
浏览/下载:15/0
  |  
提交时间:2022/01/12
Single cell Raman spectroscopy to identify different stages of proliferating human hepatocytes for cell therapy
期刊论文
STEM CELL RESEARCH & THERAPY, 2021, 卷号: 12, 期号: 1, 页码: 12
作者:
Ma, Chen
;
Zhang, Ludi
;
He, Ting
;
Cao, Huiying
;
Ren, Xiongzhao
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  |  
浏览/下载:59/0
  |  
提交时间:2021/12/01
Raman spectroscopy
Cell therapy
Identification
Proliferating human hepatocytes
Dedifferentiation
Survival-Assured Liver Injury Preconditioning (SALIC) Enables Robust Expansion of Human Hepatocytes in Fah(-/-)Rag2(-/-)IL2rg(-/-) Rats
期刊论文
ADVANCED SCIENCE, 2021, 页码: 14
作者:
Zhang, Ludi
;
Ge, Jian-Yun
;
Zheng, Yun-Wen
;
Sun, Zhen
;
Wang, Chenhua
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/11/04
bioreactor
humanized liver
liver xeno-repopulation
pharmacological study
A new mechanism of obeticholic acid on NASH treatment by inhibiting NLRP3 inflammasome activation in macrophage
期刊论文
METABOLISM-CLINICAL AND EXPERIMENTAL, 2021, 卷号: 120, 页码: 12
作者:
Huang, Suling
;
Wu, Yanwei
;
Zhao, Zhuohui
;
Wu, Bing
;
Sun, Kai
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2021/08/17
Macrophage
NLRP3 inflammasome
Hepatic lipid accumulation
NASH
FXR
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