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上海药物研究所 [9]
中国医学科学院 北京... [3]
金属研究所 [2]
河北大学 [1]
复旦大学上海医学院 [1]
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期刊论文 [16]
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Non-alcoholic fatty liver disease concerns with glucokinase activators Reply
期刊论文
LANCET DIABETES & ENDOCRINOLOGY, 2018, 卷号: 6, 期号: 9
作者:
Chen, Li
;
Li, Xiaoying
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Discovery of cycloalkyl-fused N-thiazol-2-yl-benzamides as tissue non-specific glucokinase activators: Design, synthesis, and biological evaluation
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 139, 页码: 128-152
作者:
Wang, Zhengyu
;
Shi, Xiaofan
;
Zhang, Huan
;
Yu, Liang
;
Cheng, Yanhua
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Type 2 diabetes mellitus
Hypoglycemia
Dyslipidemia
Glucokinase activators
N-Thiazol-2-yl-benzamides
Design, Synthesis and Evaluation of Novel Derivatives of Orotic Acid Amide as Potent Glucokinase Activators
期刊论文
2017, 卷号: 14, 期号: 3, 页码: 252-261
作者:
Zhang, Leilei
;
Hu, Shengquan
;
Lei, Lei
;
Zhang, Yuliang
;
Zhang, Lijing
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
Glucokinase
glucokinase activator
type 2 diabetes
Orotic acid amide derivatives
Design, Synthesis, and Activity Evaluation of GK/PPAR gamma Dual-Target-Directed Ligands as Hypoglycemic Agents
期刊论文
2014, 卷号: 9, 期号: 5,SI, 页码: 922-927
作者:
Lu, Jianxun
;
Lei, Lei
;
Huan, Yi
;
Li, Yongqiang
;
Zhang, Lijing
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/13
activators
agonists
dual targeting
glucokinase
PPAR
receptors
Discovery of novel dual-action antidiabetic agents that inhibit glycogen phosphorylase and activate glucokinase
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 58, 页码: 624-639
作者:
Zhang, Lei
;
Chen, Xiaojie
;
Liu, Jun
;
Zhu, Qingzhang
;
Leng, Ying
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Glycogen phosphorylase inhibitors
Glucokinase activators
Type 2 diabetes
Dual-target-directed
Hybrid
Investigation on the oxidation of aryl oxiranylmethanols and the synthesis of 2-aryl-N-thiazolyl-oxirane-2-carboxamides as gincokinase activators
期刊论文
TETRAHEDRON LETTERS, 2012, 卷号: 53, 期号: 35, 页码: 4738-4742
作者:
Ye, Na
;
Xu, Xiangtao
;
Li, Fuying
;
Ning, Mengmeng
;
Liu, Zhiqing
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Arylacetamides
Glucokinase activators
Ruthenium-catalyzed
Oxo-rearrangement
Design, synthesis, and pharmacological evaluation of benzamide derivatives as glucokinase activators
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2012, 卷号: 20, 期号: 9, 页码: 2982-2991
作者:
Mao, Weiwei
;
Ning, Mengmeng
;
Liu, Zhiqing
;
Zhu, Qingzhang
;
Leng, Ying
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Type 2 diabetes (T2D)
Glucokinase activator
Benzamide derivatives
Privileged-fragment-merging
Aminothiazole
Investigation on the oxidation of aryl oxiranylmethanols and the synthesis of 2-aryl-N-thiazolyl-oxirane-2-carboxamides as gincokinase activators
期刊论文
TETRAHEDRON LETTERS, 2012, 卷号: 53, 期号: 35, 页码: 4738-4742
作者:
Ye, Na[1]
;
Xu, Xiangtao[2]
;
Li, Fuying[3]
;
Ning, Mengmeng[4]
;
Liu, Zhiqing[5]
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/21
Arylacetamides
Glucokinase activators
Ruthenium-catalyzed
Oxo-rearrangement
N-(5-substituted thiazol-2-yl)-2-aryl-3-(tetrahydro-2H-pyran-4-yl) propanamides as glucokinase activators
期刊论文
MEDCHEMCOMM, 2011, 卷号: 2, 期号: 6, 页码: 531-535
作者:
Liu, Zhiqing
;
Zhu, Qingzhang
;
Li, Fuying
;
Zhang, Lina
;
Leng, Ying
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Design, synthesis and biological evaluation of novel glucokinase activators
期刊论文
2011, 卷号: 22, 期号: 1, 页码: 73-76
作者:
Li, Yong Qiang
;
Zhang, Yu Liang
;
Hu, Sheng Quan
;
Wang, Yu Ling
;
Song, Hong Rui
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/13
Diabetes
Glucokinase activators
Benzamide derivatives
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