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中国医学科学院 北京... [2]
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期刊论文 [10]
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The genomic landscape of young and old lung cancer patients highlights age-dependent mutation frequencies and clinical actionability in young patients
期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2021
作者:
Cai, Lei
;
Chen, Yong
;
Tong, Xiaoling
;
Wu, Xue
;
Bao, Hua
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2021/06/15
EGFR
ERBB2
gene fusions
tyrosine kinase inhibitors
young lung cancer patients
Are exon 19 deletions and L858R different in early stage lung adenocarcinoma?
期刊论文
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2018, 卷号: 144, 期号: 1
作者:
Zhang, Yiliang
;
Ma, Yuan
;
Li, Yuan
;
Shen, Xuxia
;
Yu, Yongfu
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
Epidermal growth factor receptor (EGFR)
Tyrosine kinase inhibitor (TKI)
Lung adenocarcinoma
A Higher Proportion of the EGFR T790M Mutation May Contribute to the Better Survival of Patients with Exon 19 Deletions Compared with Those with L858R
期刊论文
2017, 卷号: 12, 期号: 9, 页码: 1368-1375
作者:
Ke E-E
;
Zhou Qing
;
Zhang Qiu-Yi
;
Su Jian
;
Chen Zhi-Hong
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2020/01/04
T790M mutation
Exon 19 deletions
L858R mutation
Resistance mechanisms
Circulating cell-free DNA has a high degree of specificity to detect exon 19 deletions and the single-point substitution mutation L858R in non-small cell lung cancer
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 20, 页码: 29154-29165
作者:
Qian, X
;
Liu, J
;
Sun, YH
;
Wang, MF
;
Lei, HD
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/01/09
circulating cell-free DNA
non-small cell lung cancer
sensitivity
specificity
epidermal growth factor receptor
DCLAK11, a multi-tyrosine kinase inhibitor, exhibits potent antitumor and antiangiogenic activity in vitro
期刊论文
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 10, 页码: 1266-1276
作者:
Guo, Xiao-bin
;
Zhu, Wei
;
Chen, Xian-jie
;
Tong, Lin-jiang
;
Peng, Xia
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/01/08
DCLAK11
substituted pyridin-3-amine derivatives
tyrosine kinase
EGFR
HER2
VEGFR2
anticancer
anti-angiogenesis
Biological Characteristics and Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors Efficacy of EGFR Mutation and its Subtypes in Lung Adenocarcinoma
期刊论文
Pathology oncology research : POR, 2014, 卷号: 20, 期号: 2, 页码: 445-451
作者:
Lu, Rong-li
;
Hu, Cheng-Ping*
;
Yang, Hua-ping
;
Li, Yuan-yuan
;
Gu, Qi-hua
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
Lung adenocarcinoma(LAC)
Epidermal growth factor receptor (EGFR)
Erlotinib
Gefitinib
Exon 19 deletions(del 19)
Exon 21 point mutation(L858R)
LncRNA expression profiles of EGFR exon 19 deletions in lung adenocarcinoma ascertained by using microarray analysis
期刊论文
MEDICAL ONCOLOGY, 2014, 卷号: 31, 期号: [db:dc_citation_issue]
作者:
Wang, Yumin
;
Chen, Wei
;
Chen, Jie
;
Pan, Qinshi
;
Pan, Jingye
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
EGFR gene
Microarray
LncRNAs
Non-small cell lung cancer
Deletion
Lung adenocarcinoma
Analysis of Driver Mutations in Female Non-Smoker Asian Patients with Pulmonary Adenocarcinoma
期刊论文
http://dx.doi.org/10.1007/s12013-012-9384-8, 2012
Ren, Shengxiang
;
Kuang, Peng
;
Zheng, Limou
;
Su, Chunxia
;
Li, Jiayu
;
Li, Bing
;
Chen, Xiaoxia
;
Wang, Yongshen
;
KimCurran, V.
;
Liu, Lu
;
Hu, Qiong
;
Zhang, Jie
;
Tang, Liang
;
Zhou, Caicun
;
郑立谋
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/07/22
CELL LUNG-CANCER
NEVER-SMOKERS
GEFITINIB
EGFR
CHEMOTHERAPY
MULTICENTER
ERLOTINIB
KINASES
GENOME
Detection of EGFR Somatic Mutations in Non-Small Cell Lung Cancer (NSCLC) Using a Novel Mutant-Enriched Liquidchip (MEL) Technology
期刊论文
2012, 卷号: 13, 期号: 7, 页码: 1007-1011
作者:
Zhang, Li
;
Yang, Huiyi
;
Zhao, Yanwei
;
Liu, Wenchao
;
Wu, Shiyang
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/01/13
EGFR
somatic mutation
exon 19 deletions and L858R
targeted therapy
NSCLC
mutant-enriched liquidchip
Identification of EGFR kinase domain mutations among lung cancer patients in China: implication for targeted cancer therapy
期刊论文
Cell Research, 2005, 卷号: 15, 期号: 3, 页码: 212-217
作者:
Jing De ZHU
;
Duan Qing PEI
;
Xiao CHEN
;
Bao Ming QIN
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2018/12/12
Lung Cancer
Epidermal Growth Factor Receptor (Egfr)
Somatic Mutation.
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