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Key Considerations in Targeted Protein Degradation Drug Discovery and Development 期刊论文
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10
作者:  Qin, Liena;  Dai, Han;  Wang, Junfeng
收藏  |  浏览/下载:19/0  |  提交时间:2022/12/23
Deep Learning-Based Morphological Classification of Endoplasmic Reticulum Under Stress 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 卷号: 9, 页码: 13
作者:  Guo, Yuanhao;  Shen, Di;  Zhou, Yanfeng;  Yang, Yutong;  Liang, Jinzhao
收藏  |  浏览/下载:43/0  |  提交时间:2022/03/17
Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090
作者:  Jin, Tingting;  Xu, Lei;  Wang, Peipei;  Hu, Xiaobei;  Zhang, Runyuan
收藏  |  浏览/下载:23/0  |  提交时间:2022/01/04
A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies 期刊论文
MOLECULAR CELL, 2021, 卷号: 81, 期号: 19, 页码: 4076-+
作者:  Liu, Zhiwei;  Liu, Yingluo;  Qian, Lili;  Jiang, Shangwen;  Gai, Xiameng
收藏  |  浏览/下载:27/0  |  提交时间:2021/12/01
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Zhou, Yu-bo;  Zhang, Yang-ming;  Huang, Hong-hui;  Shen, Li-jing;  Han, Xiao-feng
收藏  |  浏览/下载:93/0  |  提交时间:2021/11/04
The ups, downs and new trends of IDO1 inhibitors 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 12
作者:  Chen, Shulun;  Tan, Jing;  Zhang, Ao
收藏  |  浏览/下载:14/0  |  提交时间:2021/08/17
Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 13
作者:  Gao, Feng;  Chen, Xiaoxu;  Lu, Junyan;  Hu, Shulei;  Xu, Hui
收藏  |  浏览/下载:42/0  |  提交时间:2021/05/24
SAF-248, a novel PI3K delta-selective inhibitor, potently suppresses the growth of diffuse large B-cell lymphoma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Zhang, Xi;  Duan, Yu-ting;  Wang, Yi;  Zhao, Xing-dong;  Sun, Yi-ming
收藏  |  浏览/下载:37/0  |  提交时间:2021/05/24
Adaptive resistance to PI3K alpha-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells 期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 1, 页码: 13
作者:  Wang, Yu-xiang;  Zhang, Xu;  Ma, Qing-yang;  Hu, Lan-dian;  Zhang, Xi
收藏  |  浏览/下载:47/0  |  提交时间:2021/05/24
PI3K alpha inhibitor CYH33 triggers antitumor immunity in murine breast cancer by activating CD8(+)T cells and promoting fatty acid metabolism 期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 卷号: 9, 期号: 8, 页码: 16
作者:  Sun, Pu;  Zhang, Xi;  Wang, Rong-Jing;  Ma, Qing-Yang;  Xu, Lan
收藏  |  浏览/下载:42/0  |  提交时间:2021/11/04


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