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上海药物研究所 [39]
西北高原生物研究所 [10]
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海洋研究所 [6]
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Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis
期刊论文
BIOACTIVE MATERIALS, 2022, 卷号: 17, 页码: 406-424
作者:
Wang, Jin
;
Xie, Si-an
;
Li, Ning
;
Zhang, Tao
;
Yao, Weijuan
收藏
  |  
浏览/下载:106/0
  |  
提交时间:2022/06/10
Matrix stiffness
Inflammation
DDR1
DNMT1
Mechanotransduction
Physicochemical Properties and Biological Activities of Silver Carp Scale Peptide and Its Nanofiltration Fractions
期刊论文
FRONTIERS IN NUTRITION, 2022, 卷号: 8
作者:
Zu, Xiao-yan
;
Zhao, Ya-jing
;
Fu, Shi-ming
;
Liao, Tao
;
Li, Hai-lan
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/03/01
silver carp scale peptide
physicochemical properties
free radical scavenging
tyrosinase inhibition
amino acid sequence
Electroconvulsive therapy modulates critical brain dynamics in major depressive disorder patients
期刊论文
BRAIN STIMULATION, 2022, 卷号: 15, 期号: 1, 页码: 214-225
作者:
Xin, Yumeng
;
Bai, Tongjian
;
Zhang, Ting
;
Chen, Yang
;
Wang, Kai
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/07/25
Major depressive disorder
Electroconvulsive therapy
Criticality
Neuronal avalanches
Rapid and Sensitive Detection of Water Toxicity Based on Photosynthetic Inhibition Effect
期刊论文
TOXICS, 2021, 卷号: 9
作者:
Chen, Min
;
Yin, Gaofang
;
Zhao, Nanjing
;
Gan, Tingting
;
Feng, Chun
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2022/02/14
photosynthetic inhibition
photosynthetic fluorescence parameter
Chlorella pyrenoidosa
toxic water pollutants
rapid detection
biotesting
Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors
期刊论文
PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664
作者:
Xu, Jianghong
;
Hu, Yuanyuan
;
Liu, Xiaoqi
;
Gao, Anhui
;
Gao, Lixin
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/12/01
IDH1-R132H inhibitors
synthesis
biological activity
docking
3-(indol-3-yl)-4-(pyrazolo-[3
4-c]pyridazin-3-yl)-maleimides
Recent Progress and Clinical Development of Inhibitors that Block MDM4/p53 Protein-Protein Interactions
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 15, 页码: 10621-10640
作者:
Zhang, Shiyan
;
Lou, Jianfeng
;
Li, Yafang
;
Zhou, Feilong
;
Yan, Ziqin
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2021/11/04
Distinct root system acclimation patterns of seagrass Zostera japonica in sediments of different trophic status: a research by X-ray computed tomography
期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2021, 页码: 14
作者:
Song, Xiaoyue
;
Zhou, Yi
;
Zeng, Jiangning
;
Shou, Lu
;
Zhang, Xiaomei
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/09/16
Zostera japonica
root system
acclimation pattern
sediment
trophic status
X-ray computed tomography
Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439
期刊论文
ACS INFECTIOUS DISEASES, 2021, 卷号: 7, 期号: 7, 页码: 1885-1893
作者:
Shackleford, David M.
;
Chiu, Francis C. K.
;
Katneni, Kasiram
;
Blundell, Scott
;
McLaren, Jenna
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2021/11/04
OZ439 (artefenomel)
malaria
metabolite identification
cytochrome P450 metabolism
cytochrome P450 inhibition
time-dependent inhibition
Carbon ion combined with tigecycline inhibits lung cancer cell proliferation by inducing mitochondrial dysfunction
期刊论文
LIFE SCIENCES, 2020, 卷号: 263, 页码: 10
作者:
Yan, Junfang
;
Xie, Yi
;
Wang, Fang
;
Chen, Yuhong
;
Zhang, Jinhua
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2021/12/13
Mitochondrial dysfunction
Carbon ion radiation
Tigecycline
Mitochondrial translation
Akt/AMPK/mTOR pathway
Design and synthesis of novel desfluoroquinolone-aminopyrimidine hybrids as potent anti-MRSA agents with low hERG activity
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 103, 页码: 10
作者:
Song, Runzhe
;
Wang, Yue
;
Wang, Minghui
;
Gao, Ruixuan
;
Yang, Teng
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/24
Desfluoroquinolone
Aminopyrimidine
Hybrids
Anti-MRSA
hERG activity
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