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New ophiobolin sesterterpenoid and drimane sesquiterpenoids from a marine-alga-derived fungus
Aspergillus
sp.
期刊论文
FITOTERAPIA, 2023, 卷号: 170, 页码: 6
作者:
Fang, Sheng-Tao
;
Shi, Zhen-Zhen
;
Song, Yin-Ping
;
Yin, Xiu-Li
;
Ji, Nai-Yun
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/11/15
Marine fungus
Aspergillus
Ophiobolin sesterterpenoid
Drimane sesquiterpenoid
Anti-microalgal activity
Four dodecanoic acid derivatives from the cold-seep-derived fungus Cladosporium cladosporioides 8-1
期刊论文
NATURAL PRODUCT RESEARCH, 2023, 页码: 6
作者:
Li, Chang-Peng
;
Song, Yin-Ping
;
Liang, Xiao-Rui
;
Ji, Nai-Yun
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2023/11/15
Cladosporium cladosporioides
dodecanoic acid
cladospolide
antimicroalgal activity
S3I-201 derivative incorporating naphthoquinone unit as effective STAT3 inhibitors: Design, synthesis and anti-gastric cancer evaluation
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 71
作者:
Li, Haobin
;
Cai, Maohua
;
Cao, Fei
;
Yu, Dehua
;
Yang, Jing
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/12/22
STAT3 inhibitor
Quinone derivative
S3I-201
Anti -gastric cancer drug
Talaromycone A, a New 2-Benzopyran-1,3-Dione from Talaromyces wortmannii LGT-4
期刊论文
CHEMISTRY OF NATURAL COMPOUNDS, 2022, 卷号: 58, 期号: 3, 页码: 446-449
作者:
Guo, Wen-Lin
;
Yang, Zhong-Duo
;
Li, Xiao-Fei
;
Yang, Xing
;
Yang, Li-Jun
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/07/19
endophytic fungus
Talaromyces wortmannii
2-benzopyran-1
3-dione
Tripterygium wilfordii
Integrated Transcriptomics and Reverse Pharmacophore Mapping-based Network Pharmacology to Explore the Mechanisms of Natural Compounds against Doxorubicin-induced Cardiotoxicity
期刊论文
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2022, 卷号: 25
作者:
Zhu, Junfeng
;
Yi, Xiaojiao
;
Ding, Haiying
;
Zhong, Like
;
Fang, Luo
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/12/22
Doxorubicin-induced cardiotoxicity
natural compounds
mechanism of action
gene expression profile
bioinformatics
network pharmacology
Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Zou, Hui-xi
;
Zhang, Yu-feng
;
Zhong, Da-fang
;
Jiang, Yong
;
Liu, Fei
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/01/04
furmonertinib
autoinduction
food effect
alkaline phosphatase
body weight
pharmacokinetics
modeling and simulation
NSCLC
Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14
作者:
He, Yu-Long
;
Chen, Meng-Ting
;
Wang, Ting
;
Zhang, Ming-Ming
;
Li, Ying-Xia
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2021/11/04
Type 2 diabetes mellitus
Dual FABP4/5 inhibitors
Anti-lipolytic and anti-inflammatory effects
Metabolic stability
Anti-diabetic activities
CHEMICAL CONSTITUENTS AND BIOLOGICAL ACTIVITY OF Talaromyces ruber
期刊论文
CHEMISTRY OF NATURAL COMPOUNDS, 2021, 卷号: 57, 期号: 6, 页码: 1137-1140
作者:
Wei, Han-Nan
;
Yang, Zhong-Duo
;
Zhang, Yu
;
Song, Meng-Yao
;
Yu, Xiao-Chao
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/12/17
5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:
Wang, Shuni
;
Yang, Hong
;
Su, Mingbo
;
Lian, Fulin
;
Cong, Zhanqing
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2021/11/04
NSD2
Methyltransferase
HTS
Multiple myeloma
5-Aminonaphthalene derivatives
Inhibitor
Discovery and structure - activity relationship exploration of pyrazolo [1,5-a]pyrimidine derivatives as potent FLT3-ITD inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 48, 页码: 13
作者:
Chen, Yun
;
Bai, Gang
;
Li, Yan
;
Ning, Yi
;
Cao, Sufen
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/12/01
FLT3
FLT3-ITD
Acute myeloid leukemia
Structure-activity relationships
Pyrazolo[1, 5-a]pyrimidine
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