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深圳先进技术研究院 [2]
武汉大学 [2]
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期刊论文 [12]
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2019 [1]
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Development and characterization of a CRISPR/Cas9n-based multiplex genome editing system for Bacillus subtilis
期刊论文
Biotechnology for Biofuels, 2019, 卷号: Vol.12 No.1, 页码: 1-17
作者:
Dingyu Liu
;
Can Huang
;
Jiaxin Guo
;
Peiji Zhang
;
Tao Chen
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/11/21
CRISPR/Cas9n
Multiplex genome editing
Combinatorial metabolic engineering
Riboflavin
Nick repair mechanism
MiYA, an efficient machine-learning workflow in conjunction with the YeastFab assembly strategy for combinatorial optimization of heterologous metabolic pathways in Saccharomyces cerevisiae
期刊论文
METABOLIC ENGINEERING, 2018
作者:
Zhou, Yikang
;
Li, Gang
;
Dong, Junkai
;
Xing, Xin-hui
;
Dai, Junbiao
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/31
Directed evolution of mevalonate kinase in Escherichia coli by random mutagenesis for improved lycopene
期刊论文
RSC ADVANCES, 2018, 卷号: 8, 期号: 27, 页码: 15021-15028
作者:
Chen, Hailin
;
Liu, Changqing
;
Li, Meijie
;
Zhang, Haibo
;
Xian, Mo
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  |  
浏览/下载:30/0
  |  
提交时间:2018/12/21
Streptomyces species: Ideal chassis for natural product discovery and overproduction
期刊论文
METABOLIC ENGINEERING, 2018, 卷号: 50
作者:
Liu, Ran
;
Deng, Zixin
;
Liu, Tiangang
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  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Streptomyces
Natural products
Genetic engineering
Metabolic engineering
Combinatorial biosynthesis
Heterologous expression
A homomeric geranyl diphosphate synthase-encoding gene from Camptotheca acuminata and its combinatorial optimization for production of geraniol in Escherichia coli
期刊论文
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, 2017, 卷号: 44, 期号: 10, 页码: 1431-1441
作者:
Yang, LX
;
Jiang, LZ
;
Li, W
;
Yang, Y
;
Zhang, GL
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  |  
浏览/下载:19/0
  |  
提交时间:2018/08/28
Geranyl Diphosphate Synthase
Camptotheca Acuminata
Geraniol
Metabolic Engineering
Fermentation
Releasing the potential power of terpene synthases by a robust precursor supply platform
期刊论文
METABOLIC ENGINEERING, 2017, 卷号: 42
作者:
Bian, Guangkai
;
Han, Yichao
;
Hou, Anwei
;
Yuan, Yujie
;
Liu, Xinhua
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  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
Terpenoids
Terpene synthases
Promiscuous
Protein engineering
Precursor supply
Combinatorial biosynthesis
Skeleton reframing
Construction of polyketide overproducing Escherichia coli strains via synthetic antisense RNAs based on in silico fluxome analysis and comparative transcriptome analysis
期刊论文
Biotechnology Journal, 2016
作者:
Hai-Lin Meng
;
Zhi-Qiang Xiong
;
Shu-Jie Song
;
Jian-Feng Wang
;
Yong Wang
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  |  
浏览/下载:25/0
  |  
提交时间:2017/01/13
Improvement of catechin production in Escherichia coli through combinatorial metabolic engineering
期刊论文
Metabolic Engineering, 2015, 卷号: 28, 页码: 43-53
作者:
Zhao, Shujuan
;
Jones, J. Andrew
;
Lachance, Daniel M.
;
Bhan, Namita
;
Khalidi, Omar
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  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
Improvement of catechin production in Escherichia coli through combinatorial metabolic engineering
期刊论文
METABOLIC ENGINEERING, 2015, 卷号: 28
作者:
Zhao, Shujuan
;
Jones, J. Andrew
;
Lachance, Daniel M.
;
Bhan, Namita
;
Khalidi, Omar
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Catechin
ePathBrick
Copy number balancing
NADPH availability
Protein scaffolds
Pathway optimization
Genome-scale metabolic network guided engineering of Streptomyces tsukubaensis for FK506 production improvement
期刊论文
Microbial Cell Factories, 2013, 卷号: Vol.12
作者:
Di Huang
;
Shanshan Li
;
Menglei Xia
;
Jianping Wen
;
Xiaoqiang Jia
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/02/27
Streptomyces tsukubaensis
FK506
Genome-scale metabolic model
Target prediction
Metabolic engineering
Combinatorial modification
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