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浏览/检索结果: 共6条，第1-6条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discover 4 beta-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 170, 页码: 73-86 作者:  Zhao, Wei;  He, Long;  Xiang, Tian-Le;  Tang, Ya-Jie 收藏  |  浏览/下载：6/0  |  提交时间：2019/12/11 Tubulin  Colchicine domain  Podophyllotoxin  Binding affinity  Nanomolar-potency antitumor activity   Discover 4β-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain 期刊论文 European Journal of Medicinal Chemistry, 2019, 页码: 73-86 作者:  Zhao W.;  He L.;  Xiang T.-L.;  Tang Y.-J. 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11 Binding affinity  Colchicine domain  Nanomolar-potency antitumor activity  Podophyllotoxin  Tubulin   The Structure of MT189-Tubulin Complex Provides Insights into Drug Design 期刊论文 LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 9, 页码: 1069-1073 作者:  Li, Zhongping;  Ma, Lingling;  Wu, Chengyong;  Meng, Tao;  Ma, Lanping 收藏  |  浏览/下载：7/0  |  提交时间：2020/07/01 Crystal structure  tubulin  colchicine binding site  inhibitor  MT189  drug design   Experimental and Simulation Identification of Xanthohumol as an Inhibitor and Substrate of ABCB1 期刊论文 APPLIED SCIENCES-BASEL, 2018, 卷号: 8, 期号: 5 作者:  Liu, Fangming;  Hoag, Hannah;  Wu, Chun;  Liu, Haizhou;  Yin, Hua 收藏  |  浏览/下载：5/0  |  提交时间：2019/08/19 xanthohumol  doxorubicin resistance  synergism  ABCB1   Experimental and Simulation Identification of Xanthohumol as an Inhibitor and Substrate of ABCB1 期刊论文 APPLIED SCIENCES-BASEL, 2018, 卷号: 8, 期号: 5, 页码: 681:1-11 作者:  Liu, Fangming;  Hoag, Hannah;  Wu, Chun;  Liu, Haizhou;  Yin, Hua 收藏  |  浏览/下载：4/0  |  提交时间：2018/12/07 xanthohumol  doxorubicin resistance  synergism  ABCB1   Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules 期刊论文 MOLECULAR PHARMACOLOGY, 2016, 卷号: 89, 期号: 2, 页码: 233—242 作者:  Wang, YX;  Benz, FW;  Wu, YP;  Wang, QS;  Chen, YF 收藏  |  浏览/下载：29/0  |  提交时间：2016/09/12 TUBULIN  CHEMOTHERAPY  COLCHICINE  AGENTS  LIGANDS