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A Peptide from Budding Yeast GAPDH Serves as a Promising Antifungal against Cryptococcus neoformans
期刊论文
MICROBIOLOGY SPECTRUM, 2022, 卷号: 10
作者:
Zhang, Yang
;
Zhou, Liyan
;
Liu, Yan
;
Zhao, Xi
;
Lian, Xianqiang
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2022/05/16
antifungal peptide
GAPDH
Cryptococcus neoformans
apoptosis
Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14
作者:
He, Yu-Long
;
Chen, Meng-Ting
;
Wang, Ting
;
Zhang, Ming-Ming
;
Li, Ying-Xia
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2021/11/04
Type 2 diabetes mellitus
Dual FABP4/5 inhibitors
Anti-lipolytic and anti-inflammatory effects
Metabolic stability
Anti-diabetic activities
Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:
Meng, Xiang-Dong
;
Gao, Li-Xin
;
Wang, Zhi-Jia
;
Feng, Bo
;
Zhang, Chun
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/12/01
2,5-diphenyl-1,3,4-oxadiazole derivatives
SHP2
Inhibitors
Structure-activity relationships (SAR)
Novel Non-paralytic Shellfish Toxin and Non-spirolide Toxicity to Finfish, Brine Shrimp, and Rotifer Observed in a Culture of the Dinoflagellate Alexandrium insuetum Isolated From the Coastal Water of China
期刊论文
FRONTIERS IN MARINE SCIENCE, 2021, 卷号: 8, 页码: 17
作者:
Song, Xiaoying
;
Zhai, Xinyu
;
Hao, Shuang
;
Shang, Lixia
;
Deng, Yunyan
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/12/02
harmful algal blooms (HABs)
Alexandrium insuetum
morphology
phylogeny
novel toxicity
fish kill
Discovery of High-Affinity Inhibitors of the BPTF Bromodomain
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12075-12088
作者:
Lu, Tian
;
Lu, Haibo
;
Duan, Zhe
;
Wang, Jun
;
Han, Jie
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/11/04
Identification of Novel Fused Heteroaromatics-Based MALT1 Inhibitors by High-Throughput Screening to Treat B Cell Lymphoma
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9217-9237
作者:
Liang, Xuewu
;
Sun, Chenxia
;
Li, Chunpu
;
Yu, Haolan
;
Wei, Xiaohui
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  |  
浏览/下载:21/0
  |  
提交时间:2021/08/17
Probing the Energetic Metabolism of Resting Cysts under Different Conditions from Molecular and Physiological Perspectives in the Harmful Algal Blooms-Forming Dinoflagellate Scrippsiella trochoidea
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 14, 页码: 17
作者:
Li, Fengting
;
Yang, Aoao
;
Hu, Zhangxi
;
Lin, Siheng
;
Deng, Yunyan
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2021/09/15
ATP content
ATP synthase subunit beta (beta-F-1-ATPase)
energetic metabolism
resting cyst
Scrippsiella trochoidea
suppression subtractive hybridization (SSH)
viability
Development of Potent NEDD8-Activating Enzyme Inhibitors Bearing a Pyrimidotriazole Scaffold
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 9, 页码: 6161-6178
作者:
Xiong, Chaodong
;
Zhou, Lina
;
Tan, Jing
;
Song, Shanshan
;
Bao, Xubin
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/08/17
Discovery of a Pyrimidinedione Derivative as a Potent and Orally Bioavailable Axl Inhibitor
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 7, 页码: 3956-3975
作者:
Zhang, Hefeng
;
Peng, Xia
;
Dai, Yang
;
Shao, Jingwei
;
Ji, Yinchun
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/06/11
Design, synthesis, and biological evaluation of 4-benzoylamino-1H-pyrazole-3-carboxamide derivatives as potent CDK2 inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 12
作者:
Lin, Tingting
;
Li, Jiacheng
;
Liu, Liping
;
Li, Yuanqing
;
Jiang, Hualiang
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  |  
浏览/下载:70/0
  |  
提交时间:2021/05/24
CDK2 inhibitor
Selectivity
Anti-proliferative potency
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