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上海药物研究所 [4]
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中南大学 [1]
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期刊论文 [8]
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Structural insights into the potency of SK channel positive modulators
期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:
Nam, Young-Woo
;
Orfali, Razan
;
Liu, Tingting
;
Yu, Kunqian
;
Cui, Meng
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
A novel target for cancer therapyeEF2K
期刊论文
Chemistry of Life, 2016, 卷号: 36, 期号: 3, 页码: 397-403
作者:
Xiao Ting
;
Liu Rui
;
Wang Mingwei
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/01/08
eukaryotic elongation factor 2 kinase (eEF2K)
elongation
eEF2K inhibitors
high-throughput drug screening
Mapping Central alpha-Helix Linker Mediated Conformational Transition Pathway of Calmodulin via Simple Computational Approach
期刊论文
JOURNAL OF PHYSICAL CHEMISTRY B, 2014, 卷号: 118, 期号: 32, 页码: 9677-9685
作者:
Wang, Jinan
;
Peng, Shaoliang
;
Cossins, Benjamin P.
;
Liao, Xiangke
;
Chen, Kaixian
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
Targeting the Small- and Intermediate-Conductance Ca2+-Activated Potassium Channels: The Drug-Binding Pocket at the Channel/Calmodulin Interface
期刊论文
NEUROSIGNALS, 2014, 卷号: 22, 期号: 2, 页码: 65-78
作者:
Cui, Meng
;
Qin, Guangrong
;
Yu, Kunqian
;
Bowers, M. Scott
;
Zhang, Miao
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  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Small- and intermediate-conductance Ca2+-activated potassium channels
Small-molecule positive modulators
Structure-based drug discovery
Ataxia
Alcohol use disorders
Parkinson's disease
Screening calmodulin-binding ligands using intensity-fading matrix-assisted laser desorption/ionization mass spectrometry
期刊论文
rapid communications in mass spectrometry, 2013, 卷号: 27, 期号: 13, 页码: 1527-1534
Ma L
;
Wang ZF
;
Liu S
;
Song FR
;
Liu ZQ
;
Liu SY
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2014/04/15
MALDI-TOF-MS
PROTEASE INHIBITORS
MOLECULAR-DYNAMICS
BIOLOGICAL SAMPLES
IN-VITRO
COMPLEXES
IDENTIFICATION
ANTAGONISTS
PHOSPHODIESTERASE
RESONANCE
Role of CREB in vasoactive intestinal peptide-mediated wound healing in human bronchial epithelial cells
期刊论文
Regulatory Peptides, 2009, 卷号: 153, 期号: 1-3, 页码: 64-69
作者:
Guan, Cha-Xiang*
;
Cui, Yan-Ru
;
Sun, Guo-Ying
;
Yu, Fang
;
Tang, Chun-Yan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
VIP
vasoactive intestinal peptide
HBECs
human bronchial epithelial cells
CREB
cAMP Response Element Binding Protein
EMSA
electrophoretic mobility shift assay
ASO
antisense oligonucleotides
NSO
nonsense oligonucleotide
H-7
1-(5-Isoquinolinesulfonyl)-2-methylpi perazine
H-89
dihydrochloride
W-7
N-(6-Aminohexyl)-5-chloro-1-naphthalene-Sulfonamid
SPF
S-phase fraction
PD98059
2-amino-3-methoxyflavon
Ki67
proliferating cell nuclear antigen
PI
proliferation index
PKA
protein kinase A
PKC
protein kinase C
ERK
extracellular signal-regulated kinase
CaM
calmodulin. VPAC, VIP receptor
Migration
Proliferation
Signal transduction
p-CREB
DNA binding activity
Gain and fidelity of transmission patterns at cortical excitatory unitary synapses improve spike encoding
期刊论文
JOURNAL OF CELL SCIENCE, 2008, 卷号: 121, 期号: 17, 页码: 2951-2960
Wang, Jinhui
;
王晋辉
;
Wei, Jian
;
Chen, Xin
;
Yu, Jiandong
;
Chen, Na
;
Shi, Jack
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  |  
浏览/下载:14/0
  |  
提交时间:2013/12/25
unitary synapse
synaptic plasticity
interneuron
action potential
spike timing
calcineurin
Ca(2+)-calmodulin.
Structural and dynamic characterization of a neuron-specific protein kinase C substrate, neurogranin
期刊论文
BIOCHEMISTRY, 2003, 卷号: 42, 期号: 17, 页码: 5143-5150
作者:
Ran, XY
;
Miao, HH
;
Sheu, FS
;
Yang, D
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  |  
浏览/下载:15/0
  |  
提交时间:2015/07/22
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