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上海药物研究所 [9]
合肥物质科学研究院 [4]
复旦大学上海医学院 [3]
山东大学 [2]
武汉大学 [2]
湖南大学 [2]
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期刊论文 [25]
会议论文 [1]
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2020 [2]
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Phase I dose-escalation and dose-expansion trial of CDK4/6 inhibitor FCN-437c in Chinese female patients with ER+HER2-advanced breast cancer (ABC).
期刊论文
CANCER RESEARCH, 2021, 卷号: 81
作者:
Zhang, Jian
;
Wang, Xiaojia
;
Wang, Xian
;
Hui, Aimin
;
Wu, Zhuli
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/11/01
Acid-activatible micelleplex delivering siRNA-PD-L1 for improved cancer immunotherapy of CDK4/6 inhibition
期刊论文
CHINESE CHEMICAL LETTERS, 2021, 卷号: 32, 期号: 6, 页码: 1929-1936
作者:
Gao, Jing
;
Zhang, Hanwu
;
Zhou, Fengqi
;
Hou, Bo
;
Chen, Meiwan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/08/17
Cancer immunotherapy
siRNA delivery
Acid-activatible micelleplex
CDK4
6 inhibitor
PD-L1 knockdown
Ki67 and progesterone receptor status predicts sensitivity to palbociclib: a real-world study
期刊论文
ANNALS OF TRANSLATIONAL MEDICINE, 2021, 卷号: 9
作者:
Shao, Xiying
;
Zheng, Yabing
;
Cao, Wenming
;
Shen, Xiabo
;
Li, Guangliang
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2021/06/15
Ki67
progesterone receptor
palbociclib
Case Report: Significant Response to Immune Checkpoint Inhibitor Camrelizumab in a Heavily Pretreated Advanced ER+/HER2-Breast Cancer Patient With High Tumor Mutational Burden
期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 10
作者:
Wang, Rong
;
Yang, Yuchen
;
Ye, Wei-Wu
;
Xiang, Jianxing
;
Chen, Songan
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/04/26
breast cancer
immunotherapy
biomarker
TMB
NGS
molecular monitoring
DCZ5248, a novel dual inhibitor of Hsp90 and autophagy, exerts antitumor activity against colon cancer
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Chen, Xiang-ling
;
Liu, Peng
;
Zhu, Wei-liang
;
Lou, Li-guang
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
DCZ5248
Hsp90
autophagy
lysosomal function
antitumor activity
colon cancer
Arsenic trioxide (ATO) induced degradation of Cyclin D1 sensitized PD-1/PD-L1 checkpoint inhibitor in oral and esophageal squamous cell carcinoma
期刊论文
JOURNAL OF CANCER, 2020, 卷号: 11
作者:
Zhu, Guanxia
;
Li, Xia
;
Li, Jiong
;
Zhou, Wei
;
Chen, Zhongjian
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/11/30
esophageal squamous cell carcinoma
oral squamous cell carcinoma
arsenic trioxide
cyclin D1
PD-L1
CDK4/6
Preclinical characterization of SHR6390, a novel CDK 4/6 inhibitor, invitro and in human tumor xenograft models
期刊论文
CANCER SCIENCE, 2019, 卷号: 110, 期号: 4, 页码: 1420-1430
作者:
Long, Fei
;
He, Ye
;
Fu, Haoyu
;
Li, Yun
;
Bao, Xubin
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
breast cancer
CDK 4/6
drug resistance
palbociclib
SHR6390
CDK4/6 inhibitor protects against myocardial cells apoptosis by inhibiting RB phosphorylation in H9c2 cells
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 509, 期号: 4
作者:
Li, Jing
;
Liu, Quan
;
Wang, Zhenggui
;
Wang, Yonggang
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/05
Palbociclib
High glucose
Cell cycle
ROS generation
Apoptosis
Ribociclib, a selective cyclin D kinase 4/6 inhibitor, inhibits proliferation and induces apoptosis of human cervical cancer in vitro and in vivo
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2019, 卷号: 112
作者:
Xiong, Yudi
;
Li, Tianqi
;
Assani, Ganiou
;
Ling, Huan
;
Zhou, Qian
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Cervical cancer
CDK4
CDK6
Ribociclib
Cell cycle
Cell apoptosis
Ribociclib, a selective cyclin D kinase 4/6 inhibitor, inhibits proliferation and induces apoptosis of human cervical cancer in vitro and in vivo.
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, 卷号: Vol.112, 页码: 108602
作者:
Yudi Xiong
;
Tianqi Li
;
Ganiou Assani
;
Huan Ling
;
Qian Zhou
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/17
CDK4
CDK6
Cell
apoptosis
Cell
cycle
Cervical
cancer
Ribociclib
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