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Predicting and overcoming resistance to CDK9 inhibitors for cancer therapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13
作者:
Hua, Chen
;
Shena, Lijuan
;
Zoua, Fengming
;
Wua, Yun
;
Wanga, Beilei
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/11/10
Acquired resistance mutations
CDK9 inhibitors
Transcription
Single nucleotide polymorphisms
BAY1251152
Role of FUS-CHOP in Myxoid Liposarcoma via miR-486/CDK4 Axis
期刊论文
BIOCHEMICAL GENETICS, 2021
作者:
Wu, Hao
;
Xia, Liming
;
Xu, Haichao
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/01/10
FUS-CHOP
Myxoid liposarcoma
Apoptosis
miR-486
CDK4 axis
Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:
Han, Xu
;
Song, Ning
;
Saidahmatov, Abdusaid
;
Wang, Peipei
;
Wang, Yong
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  |  
浏览/下载:17/0
  |  
提交时间:2021/12/16
Phase I dose-escalation and dose-expansion trial of CDK4/6 inhibitor FCN-437c in Chinese female patients with ER+HER2-advanced breast cancer (ABC).
期刊论文
CANCER RESEARCH, 2021, 卷号: 81
作者:
Zhang, Jian
;
Wang, Xiaojia
;
Wang, Xian
;
Hui, Aimin
;
Wu, Zhuli
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/11/01
Acid-activatible micelleplex delivering siRNA-PD-L1 for improved cancer immunotherapy of CDK4/6 inhibition
期刊论文
CHINESE CHEMICAL LETTERS, 2021, 卷号: 32, 期号: 6, 页码: 1929-1936
作者:
Gao, Jing
;
Zhang, Hanwu
;
Zhou, Fengqi
;
Hou, Bo
;
Chen, Meiwan
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  |  
浏览/下载:17/0
  |  
提交时间:2021/08/17
Cancer immunotherapy
siRNA delivery
Acid-activatible micelleplex
CDK4
6 inhibitor
PD-L1 knockdown
Design, synthesis, and biological evaluation of 4-benzoylamino-1H-pyrazole-3-carboxamide derivatives as potent CDK2 inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 12
作者:
Lin, Tingting
;
Li, Jiacheng
;
Liu, Liping
;
Li, Yuanqing
;
Jiang, Hualiang
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2021/05/24
CDK2 inhibitor
Selectivity
Anti-proliferative potency
Cyclin-dependent kinase inhibitor roscovitine attenuates liver inflammation and fibrosis by influencing initiating steps of liver injury
期刊论文
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 7, 页码: 925-941
作者:
Liu, Yanjun
;
Li, Jiacheng
;
Liao, Liping
;
Huang, Heming
;
Fan, Shijie
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  |  
浏览/下载:21/0
  |  
提交时间:2021/08/17
Ki67 and progesterone receptor status predicts sensitivity to palbociclib: a real-world study
期刊论文
ANNALS OF TRANSLATIONAL MEDICINE, 2021, 卷号: 9
作者:
Shao, Xiying
;
Zheng, Yabing
;
Cao, Wenming
;
Shen, Xiabo
;
Li, Guangliang
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  |  
浏览/下载:52/0
  |  
提交时间:2021/06/15
Ki67
progesterone receptor
palbociclib
Cediranib Induces Apoptosis, G1 Phase Cell Cycle Arrest, and Autophagy in Non-Small-Cell Lung Cancer Cell A549 In Vitro
期刊论文
BIOMED RESEARCH INTERNATIONAL, 2021, 卷号: 2021, 页码: 11
作者:
Guo, Menghuan
;
Liu, Zhiyuan
;
Si, Jing
;
Zhang, Jinhua
;
Zhao, Jin
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/12/10
Case Report: Significant Response to Immune Checkpoint Inhibitor Camrelizumab in a Heavily Pretreated Advanced ER+/HER2-Breast Cancer Patient With High Tumor Mutational Burden
期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 10
作者:
Wang, Rong
;
Yang, Yuchen
;
Ye, Wei-Wu
;
Xiang, Jianxing
;
Chen, Songan
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  |  
浏览/下载:44/0
  |  
提交时间:2021/04/26
breast cancer
immunotherapy
biomarker
TMB
NGS
molecular monitoring
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