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molecularbindingmodeofpf232798aclinicalantihivcandidateatchemokinereceptorccr5 期刊论文
中国药理学报英文版, 2019, 卷号: 040, 期号: 004, 页码: 563
作者:  Ya Zhu;  Yanlong Zhao;  Jian Li;  Hong Liu;  Qiang Zhao
收藏  |  浏览/下载:5/0  |  提交时间:2020/07/01
Structure-Based Design of 1-Heteroary1-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 21, 页码: 9621-9636
作者:  Peng, Panfeng;  Chen, Huan;  Zhu, Ya;  Wang, Zhilong;  Li, Jian
收藏  |  浏览/下载:57/0  |  提交时间:2019/01/08
Discovery and synthesis of 6,7,8,9-tetrahydro-5H-pyrido[4,3-c]azepin-5-one-based novel chemotype CCR2 antagonists via scaffold hopping strategy 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 12, 页码: 3559-3572
作者:  Qin, Li-Huai;  Wang, Zhi-Long;  Xie, Xin;  Long, Ya-Qiu
收藏  |  浏览/下载:29/0  |  提交时间:2019/01/08
Molecular binding mode of PF-232798, a clinical anti-HIV candidate, at chemokine receptor CCR5 期刊论文
Acta pharmacologica Sinica, 2018
作者:  Zhu, Ya;  Zhao, Yan-Long;  Li, Jian;  Liu, Hong;  Zhao, Qiang
收藏  |  浏览/下载:53/0  |  提交时间:2019/01/08
The dual CCR2/CCR5 chemokine receptor antagonist Cenicriviroc reduces macrophage infiltration and disease severity in Duchenne muscular dystrophy (Dmd(mdx-4Cv)) mice 期刊论文
PLOS ONE, 2018, 卷号: 13
作者:  Liang, Feng;  Giordano, Christian;  Shang, Dong;  Li, Qian;  Petrof, Basil J.
收藏  |  浏览/下载:4/0  |  提交时间:2019/11/26
Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist RevealsMechanisms of Chemokine Recognition and Molecular Mimicry by HIV 期刊论文
IMMUNITY, 2017, 卷号: 46, 期号: 6, 页码: 1005-+
作者:  Zheng, Yi;  Han, Gye Won;  Abagyan, Ruben;  Wu, Beili;  Stevens, Raymond C.
收藏  |  浏览/下载:21/0  |  提交时间:2019/01/08
Design, synthesis, and biological evaluation of novel piperidine-4-carboxamide derivatives as potent CCR5 inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 71, 页码: 259-266
作者:  Hu, Suwen;  Gu, Quan;  Wang, Zhilong;  Weng, Zhiyong;  Cai, Yunrui
收藏  |  浏览/下载:11/0  |  提交时间:2019/01/08
Structure of the CCR5 Chemokine Receptor-HIV Entry Inhibitor Maraviroc Complex 期刊论文
SCIENCE, 2013, 卷号: 341, 期号: 6152, 页码: 1387-1390
作者:  Tan, Qiuxiang;  Zhu, Ya;  Li, Jian;  Chen, Zhuxi;  Han, Gye Won
收藏  |  浏览/下载:12/0  |  提交时间:2019/01/08
Design, synthesis, and biological activity of novel 1,4-disubstituted piperidine/piperazine derivatives as CCR5 antagonist-based HIV-1 entry inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 9
作者:  Dong, Ming-xin;  Lu, Lu;  Li, Haitao;  Wang, Xiaohua;  Lu, Hong
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/19
C-c chemokine receptor type 5 (ccr5) utilization of transmitted and early founder human immunodeficiency virus type 1 envelopes and sensitivity to small-molecule ccr5 inhibitors 期刊论文
Journal of general virology, 2010, 卷号: 91, 页码: 2965-2973
作者:  Hu, Qinxue;  Huang, Xin;  Shattock, Robin J.
收藏  |  浏览/下载:14/0  |  提交时间:2019/05/09


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